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http://dx.doi.org/10.3746/jkfn.2003.32.3.469

Effects of Psyllium Husk and Glucomannan on Serum Lipids, Fecal Fat Excretion and Body Fat in Rats Fed High-Fat Diet  

임문이 (충남대학교 식품영양학과)
장순애 (코인텍 주식회사)
이승근 (코인텍 주식회사)
이선영 (충남대학교 식품영양학과)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.32, no.3, 2003 , pp. 469-473 More about this Journal
Abstract
This study was conducted to determine the effect of a mixture of two water-soluble dietary fibers, psyllium husk and glucomannan, on serum lipids, fecal fat excretion and body fat. Twenty one female Sprague-Dawley rats were randomly assigned into three groups (control, pair-fed control and test group) and fed a high saturated fat (20% lard) diet (control diet) or a test diet (psyllium husk and glucomannan added to the control diet at the level of 0.9% and 0.68%, respectively) for 8 weeks. Pair-fed control rats were allowed to eat the amount of diet consumed by test group the preceding day. The body weight gain and food efficiency ratio of test group were significantly lower compared with these of control group. The mean values of body weight gain and food efficiency ratio were lower in test group than in pair-fed control group, but the difference was not significant. There were no differences in food intake. The dry weight and water content of feces and fecal fat excretion were markedly greater in test group than in control groups. Serum total cholesterol and triacylglycerol levels were significantly lower in test group than in two control groups.1'he rats of two control groups had higher body fat contents than that of test group. These results indicate that the combination of the two water-soluble dietary fibers, psyllium husk and glucomannan, can be used as a potent lipid-lowering agent in individuals consuming high saturated fat diet.
Keywords
psyllium husk; glucomannan; body fat; serum lipids; fecal fat excretion;
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1 Yamada K, Tokunaga Y, Ikeda A, Ohkura K, Mamiya S, Kaku S, Sugano M, Tachibana H. 1999. Dietatry effect of guar gum and its partially hydrolyzed product on the lipid metabolism and immune function of Sprague-Dawley rats. Biosci Biotechnol Biochem 63: 2163-2167.   DOI   ScienceOn
2 Grundy SM. 1998. Multifactorial causation of obesity: implications for prevention. Am J Clin Nutr 67 (suppl): 563s-572s.   DOI
3 Hou YH, Zhang LS, Zhou HM, Wang RS, Zhang YZ. 1990. Influence of refined konjac meal on the levels of tissue lipids and the absorption of four minerals in rats. Biomed Environ Sci 3: 306-314.
4 Gelissen IC, Brodie B, Eastwood MA. 1994. Effect of plantago ovata (psyllium) husk and seeds on sterol metabolism: studies in normal and ileostomy subjects. Am J Clin Nutr 59: 395-400.   DOI
5 Lee KH, Park MA, Kim ES, Moon HK. 1994. A study on dietary fiber intakes of Korean. J Korean Soc Food Nutr 23: 767-773.
6 Cho JH. 2000. Effects of fructooligosaccharides and sponge cakes containing fructooligosaccharides on the rat's intestine and serum lipids. MS Thesis. Chungnam National University, Korea. p 25-26.
7 Vahouny GV, Khalafi R, Satchithanandam S, Watkins DW, Story JA, Cassidy MM, Kritchevsky D. 1987. Dietary fiber supplementation and fecal bile acid, neutral steroids and divalent cations in rats. J Nutr 117: 2009-2015.   DOI
8 Ide T, Okamatsu H, Sugano M. 1985. Regulation by dietary fats of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in rat liver. J Nutr 108: 409-424.
9 Gallaher CM, Munion J, Hesslink R Jr, Wise J, Gallaher DD. 2000. Cholesterol reduction by glucomannan and chitosan is mediated by changes in cholesterol absorption and bile acid and fat excretion in rats. J Nutr 130: 2753-2759.   DOI
10 Anderson JW, Floore TL, Geil PB, O'Neal DS, Balm TK. 1991. Hypocholesterolemic effects of different bulk-forming hydrophilic fibers as adjuncts to dietary therapy in mild to moderate hypercholesterolemia. Arch Intern Med 151: 1597-1602.   DOI   ScienceOn
11 Hozumi T, Yoshida M, Ishida Y, Mimoto H, Sawa J, Doi K, Kazumi T. 1995. Long-term effcts of dietary fibersupplementation on serum glucose and lipoprotein levels in diabetic rats fed a high cholesterol diet. Endocr J 42: 187-192.   DOI   ScienceOn
12 Arlian LG, Vyszenski-Moher DL, Lawrence AT, Schrotel KR, Ritz HL. 1992. Antigenic and allergenic analysis of psyllium seed components. J Allergy Clin Immunol 89: 866-876.   DOI
13 Slavin JL. 1994. Epidemiologic evidence for the impact of whole grains on health. Crit Rev Food Sci Nutr 34: 427-434.   DOI   ScienceOn
14 Kritchevsky D, Tepper SA, Klurfeld DM. 1995. Influence of psyllium presentations on plasma and liver lipids of cholesterol-fed rats. Artery 21: 303-311.
15 Fiordaliso M, Kok N, Desager KP, Goethals F, Deboyser D, Roberfroid M, Delzenne N. 1995. Dietary oligofructose lowers triglycerides, phospholipids and cholesterol in serum and very low density lipoproteins of rats. Lipids 30: 163-167.   DOI   ScienceOn
16 Vido L, Facchin P, Antonello I, Gobber D, Rigon F. 1993. Childhood obesity treatment: double blinded trial on dietary fibers (glucomannan) versus placebo. Padiatr Padol 28: 133-136.
17 Chai YM, Rhee SJ. 2001. Effects of dietary oligosaccharide on the blood glucose and serum lipid composition in streptozotocin-induced diabetic rats. J Korean Soc Food Sci Nutr 30: 710-716.   과학기술학회마을
18 Lee HS, Lee YK, Seo YJ. 1994. Annual changes in the estimated dietary fiber intake of Korean during 1969-1990. Korean J Nutrition 27: 59-71.   과학기술학회마을
19 Arvill A, Bodin L. 1995. Effect of short-term ingestion of konjac glucomannan on serum cholesterol in healthy men. Am J Clin Nutr 61: 585-589.   DOI
20 Bligh EG, Dyer WJ. 1959. A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37: 911-917.   DOI
21 Walsh DE, Yaghoubian V, Behforooz A. 1984. Effect of glucomannan on obese patients: a clinical study. Int J Obes 8: 289-293.
22 The Korean Nutrition Society. 2000. Recommended dietary allowances for Koreans. 7th Revision. Joongangmoonhwasa, Seoul.
23 Lee MR. 1999. Physiological effects of sponge cakes containing oligosaccharides. MS Thesis. Chungnam National University, Korea. p 40-41.
24 Oku T, Tokunaga T, Hosoya N. 1985. Neosugar-A fructooligosaccharide nonnutritive sweetener. Nutr Rev 43: 155-156.   DOI