Browse > Article
http://dx.doi.org/10.3746/jkfn.2003.32.1.119

Effect of Biologically Active Fractions from Onion on Physiological Activity and Lipid Metabolism  

Woo, Hi-Seob (School of Food Science, Dongju College)
Aan, Bong-Jeun (Faculty of Life Resources and Engineering, Kyungsan University)
Bae, Jong-Ho (Dept. of Confectionary Decoration, Daegu Future College)
Kim, Sung (Dept. of Food Science and Technology, Yeungnam University)
Choi, Hee-Jin (Dept. of Food Science and Technology, Yeungnam University)
Han, Ho-Suk (Dept. of Food Science and Technology, Yeungnam University)
Choi, Cheong (Dept. of Food Science and Technology, Yeungnam University)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.32, no.1, 2003 , pp. 119-123 More about this Journal
Abstract
From the 80% ethanol extraction of onion flesh, fraction I,II and III were separated by Sephadex LH-20 column chromatography. Fraction II and III had a high inhibitory effect on ACE and xanthine oxidase. The ACE was about 80% at 50 ppm of fraction IIand III. The xanthine oxidase was about 82.5% at 100 ppm of fraction In. This research was studied to investigate the effects of the fraction In isolated from onion on the reduction of fat accumulation in rats fed high fat diet for 2 months. The metabolism was examined by analyzing the fat in serum and liver. It was shown that cholesterol in serum was remarkably reduced in onion fraction In as compared with those of control.
Keywords
onion; biologically active substance; lipid metabolism;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Stripe F, Corte ED. 1969. The regulation of rat liver xanthine oxidase. J Biol Chem 244: 2855-3859.
2 Sheo HJ, Jung DL. 1977. The effect of onion juice on serum lipid levels in rats. J Kor Soc Food Sci Nutr 26: 1164-1172.   과학기술학회마을
3 Ha YL, Kim JO, Kim HD, Suh JK, Byon JI, Park SJ, Park KA. 1996. Analytical and extraction methods of bioactive substances for onion processings. RDA J Agric Sci (Agric Inst Cooporation) 38: 171-185.
4 Sheo HJ, Lim HJ, Jung DL. 1993. Effect of onion juice on toxicity of lead in rat. J Kor Soc Food Nutr 22: 138-143.   과학기술학회마을
5 Nicolas G, Bazan Jr. 1970. Effects of ischemia and electroconvulsive shock on free fatty acid and pool in the brain. Biochem Biophy Acta 282: 1128-1140.
6 Patall BS, Pike LM. 1995. Distribution of quercetin content in different rings of various coloured onion (Allium cepa L.) cultivars. J Horticultural Sci 70: 643-650.   DOI
7 An BJ, Lee JT, Bea MJ. 1998. Isolation of novel polyphenol from oolong tea and its effective prevention of the gout. Kor J Food Sci Technol 30: 970-975.   과학기술학회마을
8 Lee SH, Woo SJ, Koo YJ, Shin HK. 1995. Effets of mugwort, onion and polygalate radix on the intestinal environment of rats. Kor J Food Sci Technol 27: 598-604.
9 Frings CS. 1970. A colorimetric method for determination of total serum lipid based on the sulfophospho-vanillin reaction. Am J Clin Pathol 53: 80-91.
10 Kim SO, Lee MY. 2001. Effect of ethylacetate fraction of onion on lipid metabolism in high cholesterol fed rats. J Kor Soc Food Sci Nutr 30: 673-678.   과학기술학회마을
11 Park PS, Lee BR, Lee MY. 1991. Effects of onion diet on carbon tetrachloride toxicity of rats. J Kor Food Nutr 20: 121-125.   과학기술학회마을
12 Kee HJ, Park YK. 2000. Preparation and quality properties of extruded snack using onion pomace and onion. Kor J Food Sci Technol 32: 578-583.   과학기술학회마을
13 Cushman DW, Ondetti MA. 1980. Inhibitors of angiotensin converting enzyme for treatment of hypertension. Biochem Pharmacology 29: 1871-1877.   DOI   ScienceOn
14 Park PS, Lee BR, Lee MY. 1994. Effects of onion juice on ethanol-induced hepatic lipid peroxidation in rats. J Kor Food Nutr 23: 750-756.   과학기술학회마을
15 Rho SN, Han JH. 2000. Cyotoxicity of garlic and onion methanol extract on human lung cancer cell lines. J Kor Soc Food Soc Nutr 29: 870-874.   과학기술학회마을
16 Yagi K. 1987. Lipid peroxides and human disease. Chem Phuys Lipids 45: 337-341.   DOI   ScienceOn
17 Ra KS, Suh HJ, Chung SH, Son JY. 1997. Antioxidant activity of solvent extract from onion skin. Kor J Food Sci Technol 29: 595-600.   과학기술학회마을
18 Leighton T, Ginther C, Fluss L, Harter WK, Cansado J, Nortrio V. 1992. Molecular characterization of quercetin and quercetrin glycosides in allium vegetables, phenolic compounds in food and their effects on health II. ACS, Washington, D.C. p 221.
19 Lee CJ, Kim HD, Choung EH, Suh JK, Park CW, Ha JK. 2000. Reduction effect of carcinogen induced mouse epidermal and forestomach carcinogenesis by the extract of onion wastes. J Kor Soc Food Soc Nutr 29: 525-530.   과학기술학회마을
20 Lee YK, Lee HS. 1990. Effect of onion and ginger on the lipid peroxidation and fatty acid composition of mackerel during frozen storage. J Kor Soc Food Nutr 19: 321-329.   과학기술학회마을
21 Kwak HJ, Kwon YJ, Jeong PH, Kwon JH, Kim HK. 2000. Physiological activity and antioxidative effect of methanol extract from onion (Allium cepa L.). J Kor Soc Food Sci Nutr 29: 349-345.   과학기술학회마을
22 Kim JK, Cha WS, Park JH, Oh SL, Cho YJ, Chun SS, Choi C. 1997. Inhibition effect against tyrosinase of condensed tannins from Korean green tea. Kor J Food sci Technol 20: 173-177.   과학기술학회마을
23 Kim SY, Kim HS, Kim SH, Kim HS, Su IS, Chung SY. 1993. Effects of the feeding Plantycodon grandiflorum and Codonopsis lanceolata on the fatty acid composition of serum and liver in rats. J Kor Soc Food Nutr 22: 524-530.   과학기술학회마을
24 Swain T, Hillis WE, Oritega M. 1959. Phenolic constituents of Ptunus domestica. I. Quantitative analysis of phenolic constituents. J Sci Food Agric 10: 83-86.
25 Kim KM, Suh HJ, Chung SH, Cho WD, Ma SJ. 1999. Chemical structure of angiotensin converting enzyme inhibitor isolated from onion flesh. Food Sci Biotechnol 8: 329-332.   과학기술학회마을
26 Ma SJ. 2000. Inhibitory effect of onion seasoning on angiotensin converting enzyme. J Kor Soc Food Sci Nutr 29: 395-400.   과학기술학회마을
27 Rao SS, Venkatainaman PR. 1946. Investigation on antibiotics, studies on allicin, the antibacterial principles of Allium sativum L. J Sc Ind (India) 18: 31.