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http://dx.doi.org/10.13103/JFHS.2020.35.6.521

Saxitoxin and Its Analogues: Toxicity, Analytical Method, Occurrence and Safety Management  

Lee, Sang Yoo (School of Food Science and Technology, Chung-Ang University)
Im, Ju Hee (School of Food Science and Technology, Chung-Ang University)
Woo, So Young (School of Food Science and Technology, Chung-Ang University)
Choi, Hwa Young (School of Food Science and Technology, Chung-Ang University)
Park, Su Been (School of Food Science and Technology, Chung-Ang University)
Yoo, Cha Nee (School of Food Science and Technology, Chung-Ang University)
Chun, Hyang Sook (School of Food Science and Technology, Chung-Ang University)
Publication Information
Journal of Food Hygiene and Safety / v.35, no.6, 2020 , pp. 521-534 More about this Journal
Abstract
Paralytic shellfish poisoning (PSP) occurs when saxitoxin (STX), which is produced by harmful algae (dinoflagellates) and then accumulated in bivalve shellfish by filter-feeding, is consumed by humans. With recent advances in analysis technology, it has been reported that dinoflagellates also produce a variety of analogues such as the gonyautoxin (GTX) group and the N-sulfo-carbamoyl toxin (C toxin) group, in addition to STX. Accordingly, CODEX and the EFSA are stepping forward to manage STX and analogues as STX groups requiring safety management. In Korea, the occurrence of dinoflagellates producing STX analogues has already been reported, and contamination of analogues (GTX group, C toxin group) in live mussels has also been reported. In this study, in order to provide the basis for systematic monitoring and safety management of STX and analogues, their physicochemical characteristics, occurrence of dinoflagellates, toxicity and toxic equivalency factor, analytical method and occurrence were widely reviewed. This review is expected to contribute to strengthening the safety management of STX and its analogues.
Keywords
Paralytic shellfish poisoning; Saxitoxin; Analogues; Occurrence; Safety management;
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