1 |
Sasaki H, Sunagawa Y, Takahashi K, Imaizumi A, Fukuda H, Hashimoto T, Wada H, Katanasaka Y, Kakeya H, Fujita M, Hasegawa K, Morimoto T. Innovative preparation of curcumin for improved oral bioavailability. Biol. Pharm. Bull. 34: 660-665 (2011)
DOI
|
2 |
Stohs SJ, Ji J, Bucci LR, Preuss HG. A comparative pharmacokinetic assessment of a novel highly bioavailable curcumin formulation with 95% curcumin: a randomized, double-blind, crossover study. J. Am. Coll. Nutr. 37: 51-59 (2019)
DOI
|
3 |
Baell J, Walters MA. Chemical con artists foil drug discovery. Nature 513: 481-483 (2014)
DOI
|
4 |
Baker M. Chemists warn against deceptive molecules. Nature 541: 144-145 (2017)
DOI
|
5 |
Bisson J, McAlpine JB, Friesen JB, Chen S-N, Graham J, Pauli GF. Can invalid bioactives undermine natural product-based drug discovery? J. Med. Chem. 59: 1671-1690 (2016)
DOI
|
6 |
Calabrese EJ, Kozumbo WJ. The hormetic dose-response mechanism: Nrf2 activation. Pharmacol. Res. 167: 105526 (2021)
DOI
|
7 |
Cas MD, Ghidoni R. Dietary curcumin: correlation between bioavailability and health potential. Nutrients 11: 2147 (2019)
DOI
|
8 |
Giridhar K. Curcumin: Can it slow cancer growth? Available from: https://www.mayoclinic.org/diseases-conditions/cancer/expert-answers/curcumin/faq-20057858. Accessed Feb. 27, 2021. (2020)
|
9 |
Gupta SC, Patchva S, Aggarwal BB. Therapeutic roles of curcumin: lessons learned from clinical trials. AAPS J. 15: 195-218 (2013)
DOI
|
10 |
Thurston DE, Pysz I. Chemopreventive Agents. In: Chemistry and Pharmacology of Anticancer Drugs. 2nd ed., pp. 529-578. CRC Press Inc., Boca Raton, FL, USA (2021)
|
11 |
Purpura M, Lowery RP, Wilson JM, Mannan H, Munch G, Razmovski-Naumovski V. Analysis of different innovative formulations of curcumin for improved relative oral bioavailability in human subjects. Eur. J. Nutr. 57: 929-938 (2018)
DOI
|
12 |
Smith T, Kawa K, Eckl V, Morton C, Stredney R. Herbal supplement sales in US increased 8.5% in 2017, topping $8 billion. Herbal-Gram 119: 62-71 (2018)
|
13 |
Stohs SJ, Chen O, Ray SD, Ji J, Bucci LR, Preuss HG. Highly bioavailable forms of curcumin and promising avenues for curcumin-based research and application: a review. Molecules 25: 1397 (2020)
DOI
|
14 |
Vareed SK, Kakarala M, Ruffin MT, Crowell JA, Normolle DP, Djuric Z, Brenner DE. Pharmacokinetics of curcumin conjugate metabolites in healthy human subjects. Cancer Epidemiol. Biomark. Prev. 17: 1411-1417 (2008)
DOI
|
15 |
Wang Y-J, Pan M-H, Cheng A-L, Lin L-I, Ho Y-S, Hsieh C-Y, Lin J-K. Stability of curcumin in buffer solutions and characterization of its degradation products. J. Pharm. Biomed. Anal. 15: 1867-1876 (1997)
DOI
|
16 |
Yang K-Y, Lin L-C, Tseng T-Y, Wang S-C, Tsai T-H. Oral bioavailability of curcumin in rat and the herbal analysis from Curcuma longa by LC-MS/MS. J. Chromatogr. B 853: 183-189 (2007)
DOI
|
17 |
U.S. Food and Drug Administration. 187 Fake Cancer 'Cures' Consumers Should Avoid. (https://web.archive.org/web/20170502034227/ https://www.fda.gov/drugs/guidancecomplianceregulatoryinformation/enforcementactivitiesbyfda/ucm171057.htm) Archived from original on May 2, 2017. Retrieved August 11, 2021. (2017)
|
18 |
Yeung AWK, Horbanczuk M, Tzvetkov NT, Mocan A, Carradori S, Maggi F, Marchewka J, Sut S, Dall'Acqua S, Gan R-Y, Tancheva LP, Polgar T, Berindan-Neagoe I, Pirgozliev V, Smejkal K, Atanasov AG. Curcumin: total-scale analysis of the scientific literature. Molecules 24: 1393 (2019)
DOI
|
19 |
Kanai M, Imaizumi A, Otsuka Y, Sasaki H, Hashiguchi M, Tsujiko K, Matsumoto S, Ishiguro H, Chiba T. Dose-escalation and pharmacokinetic study of nanoparticle curcumin, a potential anticancer agent with improved bioavailability, in healthy human volunteers. Cancer Chemother. Pharmacol. 69: 65-70 (2012)
DOI
|
20 |
Metzler M, Pfeiffer E, Schulz SI, Dempe JS. Curcumin uptake and metabolism. BioFactors 39: 14-20 (2013)
DOI
|
21 |
Syng-ai C, Kumari AL, Khar A. Effect of curcumin on normal and tumor cells: role of glutathione and bcl-2. Mol. Cancer Ther. 3: 1101-1108 (2004)
DOI
|
22 |
Um MY, Yoon M, Lee J, Jung J, Cho S. A novel potent sleep-promoting effect of turmeric: turmeric increases non-rapid eye movement sleep in mice via histamine H1 receptor blockade. Mol. Nutr. Food Res. 65: 2100100 (2021)
DOI
|
23 |
Woo J-H, Park J-M, Jang J-H, Yang H, Surh Y-J, Na H-K. Curcumin induces expression of 15-hydroxyprostaglandin dehydrogenase in gastric mucosal cells and mouse stomach in vivo: AP-1 as a potential target. J. Nutr. Biochem. 85: 108469 (2020)
DOI
|
24 |
Burgos-Moron E, Calderon-Montano JM, Salvador J, Robles A, Lopez-Lazaro M. The dark side of curcumin. Int. J. Cancer 126: 1771-1775 (2010)
DOI
|
25 |
Ireson CR, Jones DJL, Orr S, Coughtrie MWH, Boocock DJ, Williams ML, Farmer PB, Steward WP, Gescher AJ. Metabolism of the cancer chemopreventive agent curcumin in human and rat intestine. Cancer Epidemiol. Biomark. Prev. 11: 105-111 (2002)
|
26 |
EFSA FEEDAP Panel (EFSA Panel on Additives and Products or Substances used in Animal Feed), Bampidis V, Azimonti G, de Lourdes Bastos M, Christensen H, Durjava MK, Kouba M, Lopez-Alonso M, Puente SL, Marcon F, Mayo B, Pechova A, Petkova M, Ramos e, Sanz Y, Villa RE, Woutersen R, Brantom P, Chesson A, Westendorf J, Gregoretti L, Manini P, Dusemund B. Safety and efficacy of turmeric extract, turmeric oil, turmeric oleoresin and turmeric tincture from Curcuma longa L. rhizome when used as sensory additives in feed for all animal species. EFSA J. 18: 6146 (2020)
|
27 |
Gupta SC, Prasad S, Kim JH, Patchva S, Webb LJ, Priyadarsini IK, Aggarwal BB. Multitargeting by curcumin as revealed by molecular interaction studies. Nat. Prod. Rep. 28: 1937-1955 (2011)
DOI
|
28 |
Subhan F, Khalil AAK, Bhatti MZ, Haider A, Tauseef I, Haleem SK, Ibrahim AS. Curcumin: from ancient spice to modern anti-viral drug in COVID-19 pandemic. Life Sci. 1(suppl): 69-73 (2020)
|
29 |
Heger M, van Golen RF, Broekgaarden M, Michel MC. The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancers. Pharmacol. Rev. 68: 222-307 (2014)
|
30 |
Hewlings SJ, Kalman DS. Curcumin: a review of its effects on human health. Foods 6: 92 (2017)
DOI
|
31 |
Pulido-Moran M, Moreno-Fernandez J, Ramirez-Tortosa C, RamirezTortosa M. Curcumin and health. Molecules 21: 264 (2016)
DOI
|
32 |
Pluta R, Januszewski S, Ulamek-Koziol M. Mutual two-way interactions of curcuminc and gut microbiota. Int. J. Mol. Sci. 21: 1055 (2020)
DOI
|
33 |
Dahlin JL, Nissink JWM, Strasser JM, Francis S, Higgins L, Zhou H, Zhang Z, Walters MA. PAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS. J. Med. Chem. 58: 2091-2113 (2015)
DOI
|
34 |
Ireson C, Orr S, Jones DJL, Verschoyle R, Lim C-K, Luo J-L, Howells L, Plummer S, Jukes R, Williams M, Steward WP, Gescher A. Characterization of metabolites of the chemopreventive agent curcumin in human and rat hepatocytes and in the rat in vivo, and evaluation of their ability to inhibit phorbol ester-induced prostaglandin E2 production. Cancer Res. 61: 1058-1064 (2001)
|
35 |
Priyadarsini KI. The chemistry of curcumin: from extraction to therapeutic agent. Molecules 19: 20091-20112 (2014)
DOI
|
36 |
Jamwal R. Bioavailable curcumin formulations: a review of pharmacokinetic studies in healthy volunteers. J. Integr. Med. 16: 367-374 (2018)
DOI
|
37 |
Kanai M, Otsuka Y, Otsuka K, Sato M, Nishimura T, Mori Y, Kawaguchi M, Hatano E, Kodama Y, Matsumoto S, Murakami Y, Imaizumi A, Chiba T, Nishihira J, Shibata H. A phase I study investigating the safety and pharmacokinetics of highly bioavailable curcumin (Theracurmin) in cancer patients. Cancer Chemother. Pharmacol. 71: 1521-1530 (2013)
DOI
|
38 |
Manolova Y, Deneva V, Antonov L, Drakalska E, Momekova D, Lambov N. The effect of the water on the curcumin tautomerism: a quantitative approach. Spectrochim. Acta A Mol. Biomol. Spectrosc. 132: 815-820 (2014)
DOI
|
39 |
Nelson KM, Dahlin JL, Bisson J, Graham J, Pauli GF, Walters MA. The essential medicinal chemistry of curcumin. J. Med. Chem. 60: 1620-1637 (2017)
DOI
|
40 |
Pandey A, Chaturvedi M, Mishra S, Kumar P, Somvanshi P, Chaturvedi R. Reductive metabolites of curcumin and their therapeutic effects. Heliyon 6: e05469 (2020)
DOI
|