Antiangiogenic activity of non-aqueous fraction from Sparassis crispa extract in human umbilical vein endothelial cells
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Han, Jang Mi
(Department of Pharmaceutical Engineering & Biotechnology, Sun Moon University)
Gong, So Youn (Department of Pharmaceutical Engineering & Biotechnology, Sun Moon University) Sohng, Jae Kyung (Department of Pharmaceutical Engineering & Biotechnology, Sun Moon University) Kang, Yue Jai (Department of Aquatic Life and Medical Sciences, Sun Moon University) Jung, Hye Jin (Department of Pharmaceutical Engineering & Biotechnology, Sun Moon University) |
1 | Avramis IA, Kwock R, Avramis VI. Taxotere and vincristine inhibit the secretion of the angiogenesis inducing vascular endothelial growth factor (VEGF) by wild-type and drug-resistant human leukemia T-cell lines. Anticancer Res. 21: 2281-2286 (2001) |
2 | Carmeliet P. Angiogenesis in life, disease and medicine. Nature 438: 932-936 (2005) DOI |
3 | Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 407: 249-257 (2000) DOI |
4 | Clements MK, Jones CB, Cumming M, Daoud SS. Antiangiogenic potential of camptothecin and topotecan. Cancer Chemoth. Pharm. 44: 411-416 (1999) DOI |
5 | Coultas L, Chawengsaksophak K, Rossant J. Endothelial cells and VEGF in vascular development. Nature 438: 937-945 (2005) DOI |
6 | de Falco S. Antiangiogenesis therapy: an update after the first decade. Korean J. Intern. Med. 29: 1-11 (2014) DOI |
7 |
Du J, Xu R, Hu Z, Tian Y, Zhu Y, Gu L, Zhou L. PI3K and ERKinduced Rac1 activation mediates hypoxia-induced HIF-1 |
8 | Fan TP, Yeh JC, Leung KW, Yue PY, Wong RN. Angiogenesis: From plants to blood vessels. Trends Pharmacol. Sci. 27: 297-309 (2006) DOI |
9 | Gerber HP, Mc Murtrey A, Kowalski J, Yan M, Keyt BA, Dixit V, Ferrara N. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. J. Biol. Chem. 273: 30336-30343 (1998) DOI |
10 | Han JM, Kwon HJ, Jung HJ. Tricin, 4',5,7-trihydroxy-3',5'-dimethoxyflavone, exhibits potent antiangiogenic activity in vitro. Int. J. Oncol. 49: 1497-1504 (2016) DOI |
11 | Hong KB, Hong SY, Joung EY, Kim BH, Bae SH, Park Y, Suh HJ. Hypocholesterolemic effects of the cauliflower culinary-medicinal mushroom, Sparassis crispa (Higher Basidiomycetes), in dietinduced hypercholesterolemic rats. Int. J. Med. Mushrooms 17: 965-975 (2015) DOI |
12 |
Han JM, Lee EK, Gong SY, Sohng JK, Kang YJ, Jung HJ. Sparassis crispa exerts anti-inflammatory activity via suppression of TLRmediated NF- |
13 |
Han JM, Lim HN, Jung HJ. Hovenia dulcis Thunb. and its active compound ampelopsin inhibit angiogenesis through suppression of VEGFR2 signaling and HIF- |
14 | Hicklin DJ, Ellis LM. Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J. Clin. Oncol. 23: 1011-1027 (2005) DOI |
15 |
Hida TH, Kawaminami H, Ishibashi K, Miura NN, Adachi Y, Ohno N. Oral administration of soluble |
16 | Holmes K, Roberts OL, Thomas AM, Cross MJ. Vascular endothelial growth factor receptor-2: Structure, function, intracellular signalling and therapeutic inhibition. Cell. Signal. 19: 2003-2012 (2007) DOI |
17 | Jing Y, Liu LZ, Jiang Y, Zhu Y, Guo NL, Bamett J, Rojanasakul Y, Agani F, Jiang BH. Cadmium increases HIF-1 and VEGF expression through ROS, ERK, and AKT signaling pathways and induces malignant transformation of human bronchial epithelial cells. Toxicol. Sci. 125: 10-19 (2012) DOI |
18 | Ohno N, Miura NN, Nakajima M, Yadomae T. Antitumor 1,3-betaglucan from cultured fruit body of Sparassis crispa. Biol. Pharm. Bull. 23: 866-872 (2000) DOI |
19 | Kim HH, Lee S, Singh TS, Choi JK, Shin TY, Kim SH. Sparassis crispa suppresses mast cell-mediated allergic inflammation: role of calcium, mitogen-activated protein kinase and nuclear factor-Kb. Int. J. Mol. Med. 30: 344-350 (2012) DOI |
20 | Kimura T. Natural products and biological activity of the pharmacologically active cauliflower mushroom Sparassis crispa. Biomed. Res. Int. 2013: 982317 (2013) DOI |
21 | Rajendran P, Rengarajan T, Thangavel J, Nishigaki Y, Sakthisekaran D, Sethi G. The Vascular Endothelium and Human Diseases. Int. J. Biol. Sci. 9: 1057-1069 (2013) DOI |
22 | Shi YH, Wang YX, Bingle L, Gong LH, Heng WJ, Li Y, Fang WG. In vitro study of HIF-1 activation and VEGF release by bFGF in the T47D breast cancer cell line under normotoxic conditions: involvement of PI-3K/Akt and MEK1/ERK pathways. J. Pathol. 205: 530-536 (2005) DOI |
23 | Vincent L, Kermani P, Young LM, Cheng J, Zhang F, Shido K, Lam G, Bompais-Vincent H, Zhu Z, Hicklin DJ, Bohlen P, Chaplin DJ, May C, Rafii S. Combretastatin A4 phosphate induces rapid regression of tumor neovessels and growth through interference with vascular endothelial-cadherin signaling. J. Clin. Invest. 115: 2992-3006 (2005) DOI |
24 | Yamamoto K., Kimura T. Orally and topically administered Sparassis crispa (Hanabiratake) improved healing of skin wounds in mice with streptozotocin-induced diabetes. Biosci. Biotechnol. Biochem. 77: 1303-1305 (2013) DOI |
25 | Yamamoto K, Kimura T, Sugitachi A, Matsuura N. Anti-angiogenic and anti-metastatic effects of beta-1,3-D-glucan purified from Hanabiratake, Sparassis crispa. Biol. Pharm. Bull. 32: 259-263 (2009) DOI |
26 |
Yoshida M, Hida TH, Takeshita K, Tsuboi M, Kanamori M, Akachi N, Miura NN, Adachi Y, Ohno N. Effect of Sasa veitchii extract on immunostimulating activity of |
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