Non-saponin fraction of red ginseng inhibits monocyte-to-macrophage differentiation and inflammatory responses in vitro |
Kang, Bobin
(Department of Integrated Biomedical and Life Science, Graduate School, Korea University)
Kim, Chae Young (Department of Integrated Biomedical and Life Science, Graduate School, Korea University) Hwang, Jisu (Department of Integrated Biomedical and Life Science, Graduate School, Korea University) Choi, Hyeon-Son (Department of Food Science and Technology, College of Natural Science, Seoul Women's University) |
1 | Chang H. Effect of processing methods on the saponin contents of Panax ginseng leaf-tea. J. Food Sci. Nut. 16: 46-53 (2003) |
2 | Chang YS, Chang YH, Sung JH. The effect of ginseng and caffeine products on the antioxidative activities of mouse kidney. J. Ginseng Res. 30: 15-21 (2006) DOI |
3 | Choi Kt. Botanical characteristics, pharmacological effects and medicinal components of Korean Panax ginseng CA Meyer. Acta Pharmacol. Sin. 29: 1109-18 (2008) DOI |
4 | Coussens LM, Werb Z. Inflammation and cancer. Nature 420: 860-867 (2002) DOI |
5 | Deshmane SL, Kremlev S, Amini S, Sawaya BE. Monocyte chemoattractant protein-1 (MCP-1): An overview. J. Interferon Cytokine Res. 29: 313-326 (2009) DOI |
6 | Doss G, Agoramoorthy G, Chakraborty C. TNF/TNFR: drug target for autoimmune diseases and immune-mediated inflammatory diseases. Front Biosci. (Landmark Ed.). 19: 1028-1040 (2014) DOI |
7 | Dubinski A, Zdrojewicz Z. The role of interleukin-6 in development and progression of atherosclerosis. Pol. Merkur. Lekarski. 22: 291-294 (2007) |
8 | Han BC, Ahn H, Lee J, Jeon E, Seo S, Jang KH, et al. Nonsaponin fractions of Korean Red Ginseng extracts prime activation of NLRP3 inflammasome. J. Ginseng Res. 41: 513-523 (2017) DOI |
9 | Hayden JM, Brachova L, Higgins K, Obermiller L, Sevanian A, Khandrika S. Induction of monocyte differentiation and foam cell formation in vitro by 7-ketocholesterol. J. Lipid Res. 43: 26-35 (2002) DOI |
10 | Huang J, Zhu M, Tao Y, Wang S, Chen J, Sun W. Therapeutic properties of quercetin on monosodium urate crystal-induced inflammation in rat. J. Pharm. Pahrmacol. 64: 1119-1127 (2012) DOI |
11 | Jang A, Sueng YC, Ji JG. The comparative study on physiological activity of White ginseng, Red ginseng and Black ginseng extract. J. of Digital Convergence. 14: 459-471 (2016) DOI |
12 | Jeong HJ, Lee SG, Lee EJ, Park WD, Kim JB, Kim HJ. Antioxidant activity and anti-hyperglycemic activity of medicinal herbal extracts according to extraction methods. Korean J. Food Sci. Technol. 42: 571-577 (2010) |
13 | Kobayashi EH, Suzuki T, Funayama R, Nagashima T, Hayashi M, Sekine H, et al. Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription. Nat. Commun. 7: 1-14 (2016) |
14 | Jiang Y, You XY, Fu KL, Yin WL. Effects of extract from Mangifera indica leaf on monosodium urate crystal-induced gouty arthritis in rats. Evid. Based. Complement Alternat. Med. 2012:1-6 (2012) |
15 | Kim CY, Kang BB, Suh HJ, Choi HS. Red ginseng-derived saponin fraction suppresses the obesity-induced inflammatory responses via Nrf2-HO-1 pathway in adipocyte-macrophage co-culture system. Biomed. Pharmacother. 108: 1507-1516 (2018) DOI |
16 | Kim SI, Lee YH, Kang KS. 10-Acetyl panaxytriol, a new cytotoxic polyacetylene from Panax ginseng. Yakhak Hoeji. 33:118-123 (1989) |
17 | Konno C, Hikino H. Isolation and hypoglycemic activity of panaxans M, N, O and P, glycans of Panax ginseng roots. Int. J. Crude Drug Res. 25: 53-56 (1987) DOI |
18 | Kristiansen OP, Mandrup-Poulsen T. Interleukin-6 and diabetes: the good, the bad, or the indifferent? Diabetes 54: S114-S124 (2005) DOI |
19 | Landskron G, De la Fuente M, Thuwajit P, Thuwajit C, Hermoso MA. Chronic inflammation and cytokines in the tumor microenvironment. J. Immunol Res. 2014, Article ID 149185:1-19 (2014) |
20 | Kuzmich N, Sivak K, Chubarev V, Porozov Y, Savateeva-Lyubimova T, Peri F. TLR4 signaling pathway modulators as potential therapeutics in inflammation and sepsis. Vaccines 5: 1-25 (2017) DOI |
21 | Loboda A, Damulewicz M, Pyza E, Jozkowicz A, Dulak J. Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism. Cell. Mol. Life Sci. 73: 3221-3247 (2016) DOI |
22 | Lee TS, Chau LY. Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice. Nat. Med. 8: 240-246 (2002) DOI |
23 | Lessner SM, Prado HL, Waller EK, Galis ZS. Atherosclerotic lesions grow through recruitment and proliferation of circulating monocytes in a murine model. Am. J. Pathol.160(6): 2145-55 (2002) DOI |
24 | Libby P. Inflammation and cardiovascular disease mechanisms. Am. J. Clin. Nutr. 83: 456S-460S (2006) DOI |
25 | Nam KY. The comparative understanding between red ginseng and white ginsengs, processed ginsengs (Panax ginseng CA Meyer). J. Ginseng Res. 29: 1-18 (2005) DOI |
26 | Niu J, Kolattukudy PE. Role of MCP-1 in cardiovascular disease: molecular mechanisms and clinical implications. Clin. Sci. 117: 95-109 (2009) DOI |
27 | Rao P, Knaus EE. Evolution of nonsteroidal anti-inflammatory drugs (NSAIDs): cyclooxygenase (COX) inhibition and beyond. J. Pharm. Pharm. Sci. 11: 81s-110s (2008) DOI |
28 | Rashad S, Hemingway A, Rainsford K, Revell P, Low F, Walker F. Effect of non-steroidal anti-inflammatory drugs on the course of osteoarthritis. The Lancet 334: 519-522 (1989) DOI |
29 | Soares MP, Seldon MP, Gregoire IP, Vassilevskaia T, Berberat PO, Yu J, et al. Heme oxygenase-1 modulates the expression of adhesion molecules associated with endothelial cell activation. J. Immunol. 172: 3553-3563 (2004) DOI |
30 | Swardfager W, Lanctot K, Rothenburg L, Wong A, Cappell J, Herrmann N. A meta-analysis of cytokines in Alzheimer's disease. Biol. Psychiatry 68: 930-941 (2010) DOI |
31 | Tacke F, Randolph GJ. Migratory fate and differentiation of blood monocyte subsets. Immunobiology 211: 609-618 (2006) DOI |
32 | Tafani M, Sansone L, Limana F, Arcangeli T, De Santis E, Polese M. The interplay of reactive oxygen species, hypoxia, inflammation, and sirtuins in cancer initiation and progression. Oxid. Med. Cell Longev. 2016 (2016) |
33 | Taguchi K, Motohashi H, Yamamoto M. Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution. Genes Cells 16: 123-140 (2011) DOI |
34 | Tornatore L, Thotakura AK, Bennett J, Moretti M, Franzoso G. The nuclear factor kappa B signaling pathway: integrating metabolism with inflammation. Trends Cell Biol. 22: 557-566 (2012) DOI |
35 | Wellen KE, Hotamisligil GS. Inflammation, stress, and diabetes. J. Clin. Invest. 115: 1111-1119 (2005) DOI |
36 | Yoon S, Joo C. Study on the preventive effect of ginsenosides against hypercholesterolemia and its mechanism. Korean J. Ginseng Sci. 17: 1-12 (1993) |
37 | Serhan CN, Ward PA, Gilroy DW. Fundamentals of inflammation: Cambridge University Press (2010) |