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http://dx.doi.org/10.9721/KJFST.2017.49.6.710

Anti-inflammatory and anti-atopic effects of corn silk (Zea mays L.) ethanol extracts  

Kim, Hyun Young (Crop Foundation Division, National Institute of Crop Science, Rural Development Administration)
Lee, Mi-Ja (Crop Foundation Division, National Institute of Crop Science, Rural Development Administration)
Seo, Woo Duck (Crop Foundation Division, National Institute of Crop Science, Rural Development Administration)
Choi, Sik-Won (Crop Foundation Division, National Institute of Crop Science, Rural Development Administration)
Kim, Sun Lim (Department of Central Area Crop Science, National Institute of Crop Science, Rural Development Administration)
Jung, Gun-Ho (Department of Central Area Crop Science, National Institute of Crop Science, Rural Development Administration)
Kang, Hyeon Jung (Crop Foundation Division, National Institute of Crop Science, Rural Development Administration)
Publication Information
Korean Journal of Food Science and Technology / v.49, no.6, 2017 , pp. 710-713 More about this Journal
Abstract
This study evaluates the ability of corn silk (Zea mays L.) extract to function as a natural anti-inflammatory and anti-atopic therapeutic agent. The anti-inflammatory effects of corn silk were evaluated by measuring the inhibitory activities of nitric oxide (NO) and production of tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$. Anti-atopic effects were assessed by measuring the repression of thymus and activation-regulated chemokine (TARC). These results indicated that NICS-1 (corn silk ethanol extract) and NICS-3 (high maysin corn silk ethanol extract) functioned as anti-inflammatory agents by down-regulating LPS-induced NO and TNF-${\alpha}$. Additionally, two extracts showed weak repression of TARC expression levels in tumor necrosis factor TNF-${\alpha}$ plus IFN-${\gamma}$ induced HaCaT cells, respectively. These results suggest that corn silk extracts have anti-inflammatory and anti-atopic activities, and thus have the potential to reduce and alleviate the symptoms associated with atopic dermatitis.
Keywords
corn silk; anti-inflammatory; anti-atopic;
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Times Cited By KSCI : 14  (Citation Analysis)
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