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http://dx.doi.org/10.9721/KJFST.2017.49.4.438

Biological activity of crude polyphenol fractions of Cedrela sinensis isolated using different extraction methods  

Oh, Min Hui (Department of Food and Nutrition, Yeungnam University)
Yoon, Kyung Young (Department of Food and Nutrition, Yeungnam University)
Publication Information
Korean Journal of Food Science and Technology / v.49, no.4, 2017 , pp. 438-443 More about this Journal
Abstract
The biological activity of crude polyphenol fractions (WphF, EphE, VphF, and SphF) extracted from Cedrela sinensis using hot water, ethanol, and enzymes such as Viscozyme and Shearzyme was examined in this study. The yield of VphF was the highest (43.44%) among all fractions. The total polyphenol and flavonoid content of the fractions were highest after ethanol extraction (447.98 and 337.49 mg/g, respectively). Fractions obtained after hot water and ethanol treatment showed high antioxidant activity. All fractions, except for WphF, showed a significantly higher ${\alpha}$-glucosidase inhibitory activity than the acarbose. EphF and WphF showed the high acetylcholinesterase inhibition activity. All fractions showed more than 50% tyrosinase inhibition activity at 2 mg/mL concentration. According to these results, the crude polyphenol fractions from C. sinensis showed high antioxidative, ${\alpha}$-glucosidase inhibitory, and tyrosinase inhibitory activities. This study suggests that crude polyphenol fractions from C. sinensis, especially the WphF and EphF fractions, are good sources of functional food.
Keywords
Cedrela sinensis; extraction method; antioxidant activity; polyphenol; biological activity;
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Times Cited By KSCI : 17  (Citation Analysis)
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