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http://dx.doi.org/10.9721/KJFST.2016.48.6.604

Water extracts of Eucommia ulmoides improve lipid, glucose, and antioxidant metabolism in ovariectomized rats  

Lee, Sang Chul (Collage of Agriculture and Life Sciences, Kyungpook National University)
Chung, Soo Im (Department of Food Science and Nutrition, Kyungpook National University)
Kang, Mi Young (Department of Food Science and Nutrition, Kyungpook National University)
Publication Information
Korean Journal of Food Science and Technology / v.48, no.6, 2016 , pp. 604-609 More about this Journal
Abstract
In postmenopausal women, estrogen deficiency can be associated with metabolic diseases, such as obesity, diabetes, and cardiovascular diseases. The purpose of this study was to investigate factors related to lipid, glucose and antioxidnat metabolism. Sprague-Dawley female rats were subjected to either bilateral ovariectomy or sham operation and randomly divided into 3 dietary groups, (n=8) sham-operated fed with normal diet (SHAM), ovariectomized fed with normal diet (OVX), and ovariectomized fed with normal diet supplemented with Eucommia ulmoides extract (OVX-EU). The OVX-EU group showed significantly lower body weight, triacylglycerol, and total cholesterol than that showed by the OVX group. In addition, the OVX-EU group showed improved lipogenesis, glucose-regulating enzyme activities, adipokine and antioxidant enzyme activities. These findings demonstrate that extracts from E. ulmoides extract can be used as a functional food.
Keywords
Eucommia umoides; metabolic disease; menopause; antioxidant; ovariectomized rat;
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