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http://dx.doi.org/10.9721/KJFST.2012.44.4.447

A Comparative Study of GABA, Glutamate Contents, Acetylcholinesterase Inhibition and Antiradical Activity of the Methanolic Extracts from 10 Edible Plants  

Jung, Yeon-Seop (Department of Food Science and Technology, Keimyung University)
Park, Sung-Jin (Department of Food Science and Technology, Keimyung University)
Kim, Ji-Eun (Department of Food Science and Technology, Keimyung University)
Yang, Seun-Ah (The Center for Traditional Microorganism Resources, Keimyung University)
Park, Jung-Hyun (The Center for Traditional Microorganism Resources, Keimyung University)
Kim, Jung-Hyun (Department of Applied Chemistry, Kumoh National Institute of Technology)
Jhee, Kwang-Hwan (Department of Applied Chemistry, Kumoh National Institute of Technology)
Lee, Sam-Pin (Department of Food Science and Technology, Keimyung University)
Lee, In-Seon (Department of Food Science and Technology, Keimyung University)
Publication Information
Korean Journal of Food Science and Technology / v.44, no.4, 2012 , pp. 447-451 More about this Journal
Abstract
In order to investigate the efficacies for cognitive function of edible plants, we measured the inhibitory effects of acetylcholinesterase(AChE) activity, radical scavenging activities, and the contents of GABA and glutamate in the plant extracts. Among the plant extracts, Schizandra chinensis contained the highest GABA 14.8 mg/g and the extracts of Cnidium officinale and Polygonum multiflorum also had a relatively high GABA. On the other hand, plant extracts except, Acorus gramineus, showed similar glutamate contents. S. chinensis, Hovenia dulcis, Thuja orientalis, and Eleutherococcus senticosus exhibited high inhibition against AChE activities at about 18-33% at 1 mg/mL. In addition, strong radical scavenging activities were also detected in those extracts which showed high AChE inhibition. Taken together, H. dulcis, T. orientalis, E. senticosus, and S. chinensis could be effective resources for enhancing cognitive function. Further, it was suggested that the AChE inhibitory activities of plant extracts might be related to antioxidative activity.
Keywords
edible plants extract; AChE; radical scavenging activity; GABA; glutamic acid;
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Times Cited By KSCI : 4  (Citation Analysis)
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