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http://dx.doi.org/10.9721/KJFST.2012.44.1.089

The Antioxidant and Skin Whitening Effect of Artemisia iwayomogi Extracts  

Seo, Eun-Jong (THEFACESHOP R & D Center)
Hong, Eun-Suk (THEFACESHOP R & D Center)
Choi, Min-Hee (THEFACESHOP R & D Center)
Kim, Ki-Sun (THEFACESHOP R & D Center)
Lee, Sung-Jun (THEFACESHOP R & D Center)
Publication Information
Korean Journal of Food Science and Technology / v.44, no.1, 2012 , pp. 89-93 More about this Journal
Abstract
The purpose of this study was to investigate the antioxidant and skin whitening effects of Artemisia iwayomogi extract. Artemisia iwayomogi was extracted with 100% ethanol and water. The antioxidative and skin whitening effects of these extracts were determined with in vitro assays by using 1,1-diphenyl-2-picrylhydrazyl (DPPH) method assessing the inhibitory effects on tyrosinase activity and melanogenesis in B16 melanoma cells. Radical scavenging activity of the extracts was tested by DPPH assay which showed a high DPPH radical scavenging activity ($SC_{50}$; 17.1 ppm in EtOH, 198.4 ppm in water). In term of tyrosinase inhibitory activity, Artemisia iwayomogi ethanol extract showed high inhibition activity ($IC_{50}$: 481.8 ppm). In B16 mouse melanoma cells, the ethanol extract significantly inhibited melanin synthesis by 36.8% at a concentration of 50 ppm. These results suggest that Artemisia iwayomogi ethanol extract has significant antioxidant activity and whitening activity.
Keywords
Artemisia iwayomogi; antioxidant; whitening; tyrosinase;
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Times Cited By KSCI : 10  (Citation Analysis)
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