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Comparative Study of Electron Donating Ability, Reducing Power, Antimicrobial Activity and Inhibition of ${\alpha}$-glucosidase by Sorghum bicolor Extracts  

Sa, Yeo-Jin (Department of Applied Plant Sciences, Kangwon National University)
Kim, Ju-Sung (Oriental Bio-herb Research Institute, Kangwon National University)
Kim, Myeong-Ok (Department of Applied Plant Sciences, Kangwon National University)
Jeong, Hyun-Ju (Department of Applied Plant Sciences, Kangwon National University)
Yu, Chang-Yeon (Department of Applied Plant Sciences, Kangwon National University)
Park, Dong-Sik (Funtional Food & Nutrition Division, Rural Development Administration)
Kim, Myong-Jo (Department of Applied Plant Sciences, Kangwon National University)
Publication Information
Korean Journal of Food Science and Technology / v.42, no.5, 2010 , pp. 598-604 More about this Journal
Abstract
Electron donating ability (EDA), reducing power, total phenolic contents, total flavonoid contents, antimicrobial activity, and ${\alpha}$-glucosidase inhibitory effects of twenty-two sorghum varieties were examined using ethanol extracts (70%, v/v). The electron donationg abilities (EDA) of Mesusu and Bulgeunjangmoksusu (94% at 10 ${\mu}g$/mL) indicated higher antioxidant activity compared to those of other varieties and standard antioxidants such as BHT (13%) and BHA (74%). The reducing power of Mesusu ($OD_{700}$=0.71) suggested higher antioxidant activity, which was dependent on sample concentration. Bitjarususu showed the highest content of total phenolics (22.9 mg GAE/g); however, extracts from Heuinsusu exhibited the lowest content of total phenolics (16.4 mg GAE/g). Jangmoksusu showed the highest total flavonolic contents (3.5 mg QE/g), and Sigyeongsusu and Chal (GS) susu displayed the most antibacterial activity (MIC=8 ${\mu}g$/mL) against Escherichia coli. Extracts of Bulgeunjangmoksusu, Moktaksusu, and Ginjangmoksusu showed the highest ${\alpha}$-glucosidase inhibitory effect (98%) at the concentration of 5 ${\mu}g$/mL.
Keywords
${\alpha}$-glucosidase inhibitory effect; antimicrobial activity; electron donating ability; reducing power; total phenolic contents;
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