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Effects of Anti-Helicobacter pylori IgY Powder to Protect Mice from Helicobacter pylori  

Jung, Soon-Hee (Eggbiotech Corp.)
Kim, Hyun-Jue (Eggbiotech Corp.)
Lyoo, Young-Soo (College of veterinary medicine, Konkuk University)
Rho, Jeong-Hae (Korea Food Research Institute)
Lee, Nam-Hyung (Eggbiotech Corp.)
Publication Information
Korean Journal of Food Science and Technology / v.38, no.1, 2006 , pp. 93-98 More about this Journal
Abstract
Effects of anti-Helicobacter pylori IgY powder on H. pylori infection were evaluated 3 and 7 weeks after powder feeding by urease, PCR, and histological tests, and specific IgG assay of murine gastric tissue using mouse model. To produce anti-H. pylori IgY powder, laying hens were immunized with H. pylori prior to egg yolk harvest. C57BL/6 mice showing high response to H. pylori were infected with H. pylori and fed with the anti-H. pylori IgY powder. In urease and PCR tests, urease activity and gene count of anti-H. pylori IgY powder-fed group significantly decreased in comparison with control. Histological results indicated anti-H. pylori IgY powder effectively protected mice from H. pylori.
Keywords
IgY; egg yolk; Helicohacter pylori;
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