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The Effects of Dietary Supplements Included Green Tea, Buckwheat and Grape Leaf Extract on Lipid Metabolism and on Regression of Fatty Streak Lesions in F1B Golden Syrian Hamsters Fed the Atherogenic Diet  

Kim, Young-Eon (Korea Food Research Institute)
Kwon, Eun-Kyung (Korea Food Research Institute)
Oh, Se-Wook (Korea Food Research Institute)
Han, Dae-Seok (Korea Food Research Institute)
Kim, In-Ho (Korea Food Research Institute)
Lee, Chang-Ho (Korea Food Research Institute)
Lee, Ho-Joon (Korea Food Research Institute)
Publication Information
Korean Journal of Food Science and Technology / v.37, no.6, 2005 , pp. 962-969 More about this Journal
Abstract
Effects of 5 and 10% dietary supplement tablets containing green tea, buckwheat, and grape leaf extracts on atherosclerosis, and plasma and hepatic lipid compositions in hamsters fed antherogenic diet [modified AIN-76A containing 10% coconut oil (w/w), 0.05% cholesterol] were examined. Compared to atherogenic diet only groups, addition of supplement to atherogenic diet-fed group significantly down-regulated triglyceride and total cholesterol levels in plasma and liver. F1B hamsters fed atherogenic diet had greater foam cell accumulation compared to control and those fed atherogenic diet with addition of supplement. Lipid metabolisms of plasma and liver increased with addition of supplement dose-dependently, whereas aortic lipid accumulation decreased. These results indicate tablets supplemented with green tea, buckwheat, and grape leaf extracts have potential to prevent cardiovascular diseases in golden Syrian hamsters.
Keywords
green tea; buckwheat; grape leaf; foam cell accumulation; atherosclerosis;
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