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Isolation and Identification of Two Psoralen Derivatives as Antioxidative Compounds from the Aerial Parts of Angelica keiskei  

Kim, So-Joong (Department of Food Science & Technology, and Functional Food Research Center, Chonnam National University)
Cho, Jeong-Yong (Department of Food Science & Technology, and Functional Food Research Center, Chonnam National University)
Wee, Ji-Hyang (Department of Food Science & Technology, and Functional Food Research Center, Chonnam National University)
Jang, Mi-Young (Department of Food Science & Technology, and Functional Food Research Center, Chonnam National University)
Rim, Yo-Sup (Division of Environmental and Agricultural Science, Sunchon National University)
Kim, Cheol (SHALOM Industries Co., Ltd.)
Shin, Soo-Cheol (Department of Food Science & Technology, and Functional Food Research Center, Chonnam National University)
Moon, Jae-Hak (Division of Food Science, Sunchon National University)
Park, Keun-Hyung (Department of Food Science & Technology, and Functional Food Research Center, Chonnam National University)
Publication Information
Korean Journal of Food Science and Technology / v.37, no.4, 2005 , pp. 656-659 More about this Journal
Abstract
Hot water extracts of Angelica keiskei aerial parts were solvent-fractionated with ethyl acetate (EtOAc) and buffers (5% $NaHCO_3$, pH 8.0; 1.0 N HCl, pH 3.0) to obtain EtOAc-soluble acidic and neutral fractions. EtOAc-soluble neutral fraction was purified by Sephadex LH-20 column chromatography and reverse phase HPLC. Assay for purification of antioxidative compounds was performed by spraying DPPH solution on thin layer chromatography. Two isolated substances were identified as pseudoisopsoralen and 8-methoxypsoralen(xanthotoxin) by FAB-MS and NMR analyses.
Keywords
Angelica keiskei; antioxidative compound; DPPH radical-scavenging activity; pseudoisopsoralen; 8-methoxypsoralen;
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