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Physiological Activities of Phellinus ribis Extracts  

Song, Jae-Hwan (Faculty of Life Science and Technology, Sungkyunkwan University)
Lee, Hyun-Sook (Faculty of Life Science and Technology, Sungkyunkwan University)
Hwang, Jin-Kook (Faculty of Life Science and Technology, Sungkyunkwan University)
Chung, Tae-Young (Faculty of Life Science and Technology, Sungkyunkwan University)
Hong, Sung-Ryul (Faculty of Life Science and Technology, Sungkyunkwan University)
Park, Ki-Moon (Faculty of Life Science and Technology, Sungkyunkwan University)
Publication Information
Korean Journal of Food Science and Technology / v.35, no.4, 2003 , pp. 690-695 More about this Journal
Abstract
Physiological activities of 40% ethanol extracts of Phellinus ribis were studied by employing several biological and biochemical assays. The extracts of Phellinus ribis displayed nitrate-scavenging activities (NSA) at pH 1.2 as with 64% NSA with 1.0 mg/mL of the extracts. They also had 91% 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activities at the concentration of 1.0 mg/mL. Antioxidant activities of the extracts (at 0.5 mg/mL) on the autoxidation of linoleic acid (p<0.001) were also observed.. The inhibitory effect of the extracts on angiotensin converting enzyme was 11%. Cytotoxic effects of Phellinus ribis extracts against human cancer cell tines were also examined using MTT assay. The extracts (at 50 mg/mL) had severe growth inhibitory effects on A549, Hela, AGS, and SK-Hep-1, which were 8, 44, 76 and 42%, respectively. Ames test indicated that the extracts had no mutating effects on Salmonella typhimurium TA98 and TA100.
Keywords
Phellinus ribis; antioxidant activity; radical scavenging activity; mutagenesis; cytotoxicity;
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