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Radiosensitizing and Antitumor Effect of the Seed of Benincasae hispida  

Choi, Hye-Ran (Animal Resources Research Center, Konkuk University)
Lee, Keyong-Ho (Kolon Central Research Park)
Kim, Chang-Han (Animal Resources Research Center, Konkuk University)
Publication Information
Korean Journal of Food Science and Technology / v.35, no.3, 2003 , pp. 479-482 More about this Journal
Abstract
Radiosensitizing and antitumor effects of hot water extract derived from the seed of Benincasae hispida were investigated. The extract showed maximum survival rate of 21% at 0.1 g/kg against L1210 cells implanted in BDF1 mice. Radiosensitivity of human tumor cell line was evaluated through sulforhodamine assay. Inhibition rate of SK-OV-3 cells after 5 Gy radiation by Benincasae hispida seed extract at 2 mg/mL was 86%.
Keywords
Benincasae hispida; antitumor; radiosensitivity;
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