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Protective Effects of Water/Methanol Extracts of Cricket on the Acute Hepatic Damages in the ICR-mice Induced by Administration of $CCl_4$  

Ahn, Mi-Young (Department of Sericulture and Entomology, National Institute of Agricultural Science and Technology, RDA)
Lee, Yong-Woo (Department of Sericulture and Entomology, National Institute of Agricultural Science and Technology, RDA)
Ryu, Kang-Sun (Department of Sericulture and Entomology, National Institute of Agricultural Science and Technology, RDA)
Lee, Heui-Sam (Department of Sericulture and Entomology, National Institute of Agricultural Science and Technology, RDA)
Kim, Ik-Soo (Department of Sericulture and Entomology, National Institute of Agricultural Science and Technology, RDA)
Kim, Jin-Won (Department of Sericulture and Entomology, National Institute of Agricultural Science and Technology, RDA)
Lee, Yong-Ki (Department of Sericulture and Entomology, National Institute of Agricultural Science and Technology, RDA)
Kim, Eun-Sun (Department of Sericulture and Entomology, National Institute of Agricultural Science and Technology, RDA)
Kim, Yeong-Shik (Natural Products Research Institute, Seoul National University)
Publication Information
Korean Journal of Food Science and Technology / v.34, no.4, 2002 , pp. 684-687 More about this Journal
Abstract
Water and methanol extracts of cricket were examined for their liver protective effects against $CCl_4-intoxication$ in ICR-mice. Serum transaminases (S-GOT and S-GPT), lactate dehydrogense (LDH) and glutathione-S-transferase (GST) activities and TBARS (Thiobarbiturate-reactive substances) content were measured for evaluation of liver protective effects. The activities of GOT, GPT, LDH and hepatic content of lipid peroxide after $CCl_4-treatment$ were higher than normal control but those levels decreased th 74, 50, 101 and 40%, respectively, by the treatment of cricket methanol extract. The anti-fatigue effects of water and methanol extracts investigated by an acute weight-loaded forced swimming test showed significantly prolonged swimming time in the mice administered cricket extracts. These results suggest us that water/alcohol extract of G. bimaculatus may be used as a liver protective food.
Keywords
cricket; hepatoprotective effect; anti-fatigue effect; antilipidperoxidation;
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