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Simultaneous Analysis Method of BPA, BPF, BADGE, BFDGE and Their Degradation Products in Canned Foods and Food Simulants by HPLC  

Choi, Jae-Chun (Department of Applied Biology and Chemistry, KunKuK University)
Kyung, Suk-Hun (Department of Applied Biology and Chemistry, KunKuK University)
Lee, Gun-Tack (Department of Food Sciences, Kangnung National University)
Lee, Kwang-Ho (Division of Food Packaging, Korea Food and Drug Administration)
Publication Information
Korean Journal of Food Science and Technology / v.34, no.2, 2002 , pp. 174-179 More about this Journal
Abstract
A simple and sensitive analysis method based on reverse phase (RP) HPCL with flourescence detector was developed for simultaneous determination of bisphenol A (BPA), bisphenol F (BPF), bisphenol A diglycidyl ether (BADGE), bisphenol F diglycidyl ether (BFDGE), and their degradation products, $BADGE{\cdot}H_2O$, $BADGE{\cdot}2H_2O$, $BFDGE{\cdot}H_2O$, $BFDGE{\cdot}2H_2O$, $BADGE{\cdot}HCl{\cdot}H_2O$, $BADGE{\cdot}HCl$, $BADGE{\cdot}2HCl$, $BFDGE{\cdot}HCl{\cdot}H_2O$, $BFDGE{\cdot}HCl$ and $BFDGE{\cdot}2HCl$, which were hydrolyzed and chlorinated forms of BADGE and BFDGE, in canned foods and food simulants. These compounds were identified by GC/MSD with $MSTFA-NH_4I-DTE$ derivatization. Recovery study was performed at each 100 ng/mL levels of BPA, BPF, BADGE and BFDGE added to canned foods and food simulants. This method was resulted in recovery of $90{\sim}114%$ with relative standard deviation of $4.1{\sim}7.0%$, detection limits of $6{\sim}11$ ng/mL and quantitation limits of $12{\sim}18\;ng/mL$. Calibration curves were linear with correlatin coefficients of 0.997 for BPF, 0.996 for BPA, 0.9987 for BFDGE, and 0.9989 for BADGE.
Keywords
RP HPLC; BPA; BPF; BADGE; BFDGE; $MSTFA-NH_{4}I-DTE$; canned foods; food simulants;
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