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http://dx.doi.org/10.3339/jkspn.2018.22.2.81

A Pediatric Case of Inflammatory Bowel Disease with Renal Amyloidosis  

Hyun, Hyesun (Department of Pediatrics, Seoul National University Children's Hospital)
Park, Eujin (Department of Pediatrics, Seoul National University Children's Hospital)
Kim, Ji Hyun (Department of Pediatrics, Seoul National University Children's Hospital)
Cho, Myung Hyun (Department of Pediatrics, Seoul National University Children's Hospital)
Kang, Hee Gyung (Department of Pediatrics, Seoul National University Children's Hospital)
Moon, Jin Soo (Department of Pediatrics, Seoul National University Children's Hospital)
Moon, Kyung Chul (Department of Pathology, Seoul National University Hospital)
Ha, Il-Soo (Department of Pediatrics, Seoul National University Children's Hospital)
Cheong, Hae Il (Department of Pediatrics, Seoul National University Children's Hospital)
Publication Information
Childhood Kidney Diseases / v.22, no.2, 2018 , pp. 81-85 More about this Journal
Abstract
Amyloidosis is a rare disease that results from the deposition of extracellular protein in various body tissues, causing progressive organ dysfunction. Secondary renal amyloidosis is a rare but serious complication of chronic inflammatory bowel disease, particularly in patients with Crohn's disease or ulcerative colitis. We report a case of secondary renal amyloidosis in a pediatric patient who reported a 16-year history of "very early onset inflammatory bowel disease". Intensive treatment including repeated infliximab infusions improved clinical parameters of inflammatory bowel disease, although renal dysfunction showed progression. Amyloidosis should be considered in patients with IBD, particularly if they suffered disease progression.
Keywords
Renal amyloidosis; Crohn's disease; Very early onset inflammatory bowel disease;
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