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http://dx.doi.org/10.3339/jkspn.2014.18.2.128

A Case of "Full-house" Nephropathy in a Non-lupus Patient  

Yoo, Ha Yeong (Department of Pediatrics, Konkuk University Medical Center, Konkuk University School of Medicine)
Son, Mikyung (Department of Pediatrics, Konkuk University Medical Center, Konkuk University School of Medicine)
Cho, Myung Hyun (Department of Pediatrics, Konkuk University Medical Center, Konkuk University School of Medicine)
Kwak, Byung Ok (Department of Pediatrics, Konkuk University Medical Center, Konkuk University School of Medicine)
Park, Hye Won (Department of Pediatrics, Konkuk University Medical Center, Konkuk University School of Medicine)
Lim, So Dug (Department of Pathology, Konkuk University Medical Center, Konkuk University School of Medicine)
Chung, Sochung (Department of Pediatrics, Konkuk University Medical Center, Konkuk University School of Medicine)
Kim, Kyo Sun (Department of Pediatrics, Konkuk University Medical Center, Konkuk University School of Medicine)
Publication Information
Childhood Kidney Diseases / v.18, no.2, 2014 , pp. 128-131 More about this Journal
Abstract
Histopathologic evidence of "full-house" immune complex deposits is a pathognomonic feature of lupus nephritis. This report presents the case of a 12-year-old boy with persistent microscopic hematuria and proteinuria. He was diagnosed with "full-house" nephropathy based on a renal biopsy. However, there was no other clinical or biological evidence of systemic lupus erythematosus (SLE). Although the potential for isolated "full-house" nephropathy preceding SLE is unclear, such patients should be followed for clinical signs and autoantibodies of SLE. In most cases, microscopic hematuria has a good prognosis, and follow-up usually requires only regular urinalysis. However, we should be aware of isolated "full-house" nephropathy that remains asymptomatic for a long time, as few patients with no clinical signs and negative serology ultimately develop SLE.
Keywords
Lupus nephritis; Immunofluorescence; Systemic lupus erythematosus; Biopsy;
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