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A study on the provide of CMR substances information for Threshold Limit Values (TLVs) chemicals in KMoEL  

Lee, Kwon Seob (Occupational Safety & Health Research Institute, Korea Occupational Safety & Health Agency)
Lee, Hye Jin (Occupational Safety & Health Research Institute, Korea Occupational Safety & Health Agency)
Lee, Jong Han (Occupational Safety & Health Research Institute, Korea Occupational Safety & Health Agency)
Publication Information
Journal of Korean Society of Occupational and Environmental Hygiene / v.22, no.1, 2012 , pp. 82-90 More about this Journal
Abstract
Objectives: This study was performed to provide workplaces with political guidelines that apply international CMRs (Carcinogens, Mutagens, Reproductive toxins) information to Public Notice of TLVs (Threshold Limit Values). We analyzed information supply status about CMRs of international agencies and compared substances for which TLVs are set in KMoEL (Ministry of Employment and Labor in Korea). Methods: We referred to the reliable literature about classification criteria of CMRs corresponding to UN GHS (Globally Harmonized System of classification and Labeling of chemicals) and Public Notice No. 2009-68 'Standard for Classification, Labeling of Chemical Substance and Material Safety Data Sheet' in KMoEL. The classification system of CMRs in professional organizations (IARC, NTP, ACGIH, EU ECHA, KMoEL, etc.) was investigated through the internet and literature. Conclusions: 191 chemical substances among total 650 substances with TLVs are classified as carcinogens. Also, 43 substances classified as mutagens, and 44 as reproductive toxicants. These results suggest that the information of CMRs in Public Notice of TLV will be reorganized to 191 carcinogens, 43 mutagens, and 44 reproductive toxicants.
Keywords
Carcinogenicity; CMR; Germ cell mutagenicity; Globally Harmonization System (GHS); Reproductive toxicity; Threshold Limit Values (TLVs);
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