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Seroprevalence of Hepatitis A in a Manufacture Workplace  

Kim, Hyun-Soo (Department of Occupational and Environmental Medicine, University of Ulsan, College of Medicine, Ulsan University Hospital)
Sim, Chang-Sun (Department of Occupational and Environmental Medicine, University of Ulsan, College of Medicine, Ulsan University Hospital)
Yoon, Jae-Kook (Department of Occupational and Environmental Medicine, University of Ulsan, College of Medicine, Ulsan University Hospital)
Lee, Hun (Department of Occupational and Environmental Medicine, University of Ulsan, College of Medicine, Ulsan University Hospital)
Yoo, Cheol-In (Department of Occupational and Environmental Medicine, University of Ulsan, College of Medicine, Ulsan University Hospital)
Publication Information
Annals of Occupational and Environmental Medicine / v.22, no.4, 2010 , pp. 356-363 More about this Journal
Abstract
Objectives: The prevalence of hepatitis A decreases with improved hygiene and changing lifestyle. However, hepatitis A remains a global problem causing sporadic food-borne infections. Over the past 5 years, hepatitis A incidence has increased, and 15 deaths were reported in 2009 in Korea. Concerns about hepatitis A infection have increased. We checked hepatitis A virus antibody (HAV anti-IgG) in a large manufacturing company, so that the results could be a guideline for workplace preventive plan and health policy for hepatitis A. Methods: We investigated the seroprevalence of HAV anti-IgG and the demographic characteristics of employee volunteer, in a company in Ulsan. In addition, we estimated those factors that affected seroprevalence of HAV anti-IgG. Results: A total of 2,719 employee volunteers were enrolled into the study. The seropositive rate of HAV anti-IgG was 69.8% (n=1,899) and, the seronegative rate was 30.2% (n=820). There were no enrolled employees under age 24 years who tested positive for HAV anti-IgG; in this group, the seropositive rate was 0.0% (n=0); in 25~29 years the rate was 3.9% (n=12) and 26.5% (n=118) in 30~34 years olds. In the 35-39 ears, 61.1% (n=203) tested HAV anti-IgG positive and 86.8% (n=256) of 40~44 years tested positive. Other group tested as follows: 96.5% (n=335) in 45~49 year olds, 98.7% (n=593) in 50~54 year olds, and 100% (n=382) in over 55 years. There was a significantly increasing tendency to test HAV anti-IgG positive according to age group. In the 34-35 year olds, the seropositive rate exceeded the seronegative rate. Conclusions: HAV anti-IgG seropositive rate increased according to age. The result can used for guideline recommendationsand establishing hepatitis A policies.
Keywords
Hepatitis A; Seroprevalence; Hepatitis A antibodies;
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Times Cited By KSCI : 7  (Citation Analysis)
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