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http://dx.doi.org/10.12772/TSE.2020.57.186

Production of Collagen Nanofiber Using Electrospinning Dope of Acid-soluble Collagen Isolated from Fish Skin  

Oh, Sang Youn (Korea High Tech Institute)
Jung, Koo (Korea High Tech Institute)
Kim, Eui Hwa (Department of Textile Materials Engineering, Shinhan University)
Publication Information
Textile Science and Engineering / v.57, no.3, 2020 , pp. 186-191 More about this Journal
Abstract
Collagen is a natural, biocompatible, and biodegradable material with low immunogenicity, which is useful for tissue and organ formation and in multiple cellular functions. Moreover, Type I collagen is known to be a suitable material for medical applications. In this study, acid-soluble Type I collagen isolated from fish skin was used to make nanofibers through electrospinning using a high concentration of collagen solutions prepared by dissolving the collagen to 18 wt% in 20 wt% acetic acid at 20 ℃. The collagen and collagen nanofiber were Type I collagen subjected to sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis. The nonaqueous collagen nanofiber was heat-treated, which yielded a chemical crosslinking agent, such as polyacrylic acid, besides collagen.
Keywords
fish skin; collagen; type I collagen; electro-spinning; crosslinking; non aqueous collagen nanofiber;
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