Browse > Article
http://dx.doi.org/10.12772/TSE.2013.50.323

Preparation of Alginate Nanofiber via Electrospinning and Crosslinking  

Ku, Min Kyung (Department of Organic and Nano System Engineering, Konkuk University)
Yang, Jin Uk (Department of Organic and Nano System Engineering, Konkuk University)
Kim, Hyungsup (Department of Organic and Nano System Engineering, Konkuk University)
Publication Information
Textile Science and Engineering / v.50, no.5, 2013 , pp. 323-327 More about this Journal
Abstract
In this study, alginate fiber prepared by electrospinning was crosslinked using CaCl2. In order to improve the spinnability, glycerol was added to the aqueous solution of sodium alginate. The solution containing glycerol exhibited the crossover point of G' and G" at low frequencies and decreased the solution viscosity. A solution containing 4 wt% alginate was suitable for electrospinning and maintained the fiber shape. At higher alginate concentrations, the electrospun fiber transformed into a membrane-like structure. The crosslinked web exhibited improved thermal stability and reduced crystallinity.
Keywords
alginate; electrospinning; glycerol; calcium chloride; crosslinking;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 M. Avella, E. D. Pace, B. Immirzi, G. Impallomeni, M. Malinconico, and G. Santagata, “Addition of Glycerol Plasticizer to Seaweeds Derived Alginates: Influence of Microstructure on Chemical-physical Properties”, Carbohydr Polym, 2007, 69, 503-511.   DOI   ScienceOn
2 A. H. Clark and S. B. Ross-Murphy, “Structural and Mechanical Properties of Biopolymers Gels”, Adv Polym Sci, 1987, 83, 57-192.   DOI
3 M. Florea-Spiroiu, D. Bala, A. Balan, C. Nichita, and I. Stamatin, "Alginate Matrices Prepared In Sub and Supercritical $CO_{2}$", Digest J Nanomater Biostruct, 2012, 7, 1549-1555.
4 H. Nie, A. He, J. Zheng, S. Xu, J. Li, and C. C. Han, “Effects of Chain Conformation and Entanglement on the Electrospinning of Pure Alginate”, Biomacromolecules, 2008, 9, 1362-1365.   DOI   ScienceOn
5 W. Mackie, S. Perez, R. Rizzo, F. Taravel, and M. Vignon, “Aspects of the Conformation of Polyguluronate in the Solid State and in Solution”, Int J Biol Macromol, 1983, 5, 329-341.   DOI   ScienceOn
6 S. Salmieri and M. Lacroix, “Physicochemical Properties of Alginate/Polycaprolactone-Based Films Containing Essential Oils”, J Agric Food Chem, 2006, 54, 10205-10214.   DOI   ScienceOn
7 S. Hirano, C. Mizutani, R. Yamaguchi, and O. Miura, “Formatoin of the Polyelectrolyte Complexes of Some Acidic Glycosaminoglycans with Partially N-acylated Chitosans”, Biopolymers, 1978, 17, 805-810.   DOI
8 J. W. Lu, Y. L. Zhu, Z. X. Guo, P. Hu, and J. Yu, “Electro- spinning of Sodium Alginate with Poly(ethylene oxide)”, Polymer, 2006, 47, 8026-8031.   DOI   ScienceOn
9 A. Saarai, V. Kasparkova, T. Sedlacek, and P. Saha, "A Comparative Study of Crosslinked Sodium Alginate/Gelatin Hydrogels for Wound Dressing", Recent Researches in Geography, Geology, Energy, Environment and Biomedicine, 2011, 384-389.
10 S. H. Yuk, S. H. Cho, and H. B. Lee, “pH-sensitive Drug Delivery System Using O/W Emulsion”, J Control Release, 1995, 7, 69-74.
11 P. R. Hari, T. Chandy, and C. P. Sharma, “Chitosan/calciumalginate Beads for Oral Delivery of Insulin”, J Appl Polym Sci, 1996, 59, 1795-1801.   DOI
12 C. J. Knill, J. F. Kennedy, J. Mistry, M. Miraftab, G. Smart, M. R. Groocock, and H. J. Williams, “Alginate Fibres Modified with Unhydrolysed and Hydrolysed Chitosans for Wound Dressings”, Carbohydr Polym, 2004, 55, 65-76.   DOI   ScienceOn
13 L. L. Lloyd, J. F. Kennedya, P. Methacanoa, M. Paterson, and C. J. Knill, “Carbohydrate Polymers as Wound Management Aids”, Carbohydr Polym, 1998, 37, 315-322.   DOI   ScienceOn
14 A. D. Augst, H. J. Kong, and D. J. Mooney, “Alginate Hydrogels as Biomaterials”, Macromol Biosci, 2006, 6, 623-633.   DOI   ScienceOn
15 N. Bhattarai, Z. Li, D. Edmondson, and M. Zhang, "Alginate- Based Nanofibrous Scaffolds: Structural, Mechanical, and Biological Properties", Adv Mater, 2006, 18, 1463-1467.   DOI   ScienceOn
16 E. Alsberg, K. W. Anderson, A. Albeiruti, J. A. Rowley, and D. J. Mooney, “Engineering Growing Tissues”, Proceedings of the National Academy of Sciences of the United States of America, 2002, 99, 12025-12030.   DOI   ScienceOn
17 C. D. Saquing, C. Tang, B. Monian, C. A. Bonino, J. L. Manasco, E. Alsberg, and S. A. Khan, “Alginate-Polyethylene Oxide Blend Nanofibers and the Role of the Carrier Polymer in Electrospinning”, Ind Eng Chem Res, 2013, 52, 8692-8704.   DOI   ScienceOn
18 Q. Wang, X. Hu, Y. Dua, and J. F. Kennedy, “Alginate/starch Blend Fibers and Their Properties for Drug Controlled Release”, Carbohydr Polym, 2010, 82, 842-847.   DOI   ScienceOn
19 S. Safi, M. Morshed, S. A. Hosseini Ravandi, and M. Ghiaci, "Study of Electrospinning of Sodium Alginate, Blended Solutions of Sodium Alginate/poly(vinyl alcohol) and Sodium Alginate/poly(ethylene oxide)", J Appl Polym Sci, 2007, 104, 3245-3255.   DOI   ScienceOn
20 Z. Dong, Q. Wang, and Y. Du, “Alginate/gelatin Blend Films and Their Properties for Drug Controlled Release”, J Memb Sci, 2006, 280, 37-44.   DOI   ScienceOn
21 H. M. Fahmy and M. M. G. Fouda, “Crosslinking of Alginic Acid/chitosan Matrices Using Polycarboxylic Acids and Their Utilization for Sodium Diclofenac Release”, Carbohydr Polym, 2008, 73, 606-611.   DOI   ScienceOn
22 L. Fan, Y. Du, B. Zhang, J. Yang, J. Zhou, and J. F. Kennedy, “Preparation and Properties of Alginate/carboxymethyl Chitosan Blend Fibers”, Carbohydr Polym, 2006, 65, 447-452.   DOI   ScienceOn
23 S. Zhang and J. Luo, “Preparation and Properties of Bacterial Cellulose/Alginate Blend Bio-Fibers”, J Eng Fibers Fabrics, 2011, 6, 69-72.
24 P. Sundarrajan, P. Eswaran, A. Marimuthu, L. B. Subhadra, and P. Kannaiyan, “One Pot Synthesis and Characterization of Alginate Stabilized Semiconductor Nanoparticles”, Bull Korean Chem Soc, 2012, 33, 3218-3224.   DOI   ScienceOn