Browse > Article

Preparation of Chitosan Films Containing Hydroxyapatite Nanoparticle by Citric Acid Addition  

정용식 (전북대학교 섬유공학과)
최충열 (전북대학교 섬유공학과)
이근완 (산업자원부 기술표준원 고분자섬유과)
좌용호 (한양대학교 신소재기술전공)
박병기 (전북대학교 섬유공학과)
Publication Information
Textile Science and Engineering / v.39, no.4, 2002 , pp. 383-389 More about this Journal
Abstract
Nano-structured hydroxyapatite(HAp)/chitosan composites and their transparent films were prepared by the co-precipitation and solvent casting method. According to TEM observation, HAp particles with 100~150nm in length and 10~20nm in width were formed in the composites. We investigated the role of citric acid in the HAp/chitosan film formation. The HAp/chitosan films were prepared at various concentrations of citric acid. HAp particles did not aggregate in the chitosan matrix above 50％ citric acid concentration for the HAp content. The inhibition effects result from the adsorption of citric acid on the surface of HAp particles by ionic exchange of phosphate ions with citrate ions at the HAp/chitosan composite solution, which is caused by a higher affinity of citrate than phosphate species for the Ca-site on the HAp surface.
Keywords
hydroxyapatite(HAp); chitosan; nano-structure; aggregation; citric acid; transparent film;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 The Role of pH in the adsorption of Eitrate Ions on Hydroxyapatite /
[ L.M.Anabel;G.M.Jaime;R.C.Rafael ] / J.Colloid Interface Sci   DOI   ScienceOn
2 Biointegrated Hydroxyapatite Coated Dental Implants:5-year Clinical Observations /
[ J.N.Kent;M.S.Block;I.M.Finger;L.Guerra;H.Lasen;D.J.Misiek ] / J.Am.Dent.Assoc   DOI
3 Apatite Formation on/in Hyfrogel Matrices Using an Altermate Soaking Process(Ⅱ)-Effect of Swelling Fatios of Poly(vinyl alcohol)Hydrogel Matrices on Apatite Formation /
[ T.Taguchi;A KIshida;M.Akashi ] / J.Biomater.Sci.Polym   DOI   ScienceOn
4 Hydroxyapatite Alveolar Ridge Reconstraction:Clinical Experience, Complication and Technical Modifications /
[ J.N.Kent;I.M.Figner;J.H.Quinn;L.R.Guerra ] / J.Oral Amaxilofac Surg   DOI   ScienceOn
5 Preparation and Microstructure Analysis of Chitosan/Hydroxyapatite Nanocomposites /
[ I.Yamaguchi;k.Tokuchi;H.Fukuzaki;Y.Koyama;K.Takakuda;H.Monma;J.Tanaka ] / J.Biomed.Mater.Res   DOI   ScienceOn
6 Effect of Citric Acid on the Nucleation of Hydroxyapatite in a Simulated Body Fluid /
[ S.H.Rhee and J.Tanaka ] / Biomaterials   DOI   ScienceOn
7 Biodegradation Behavior of Ultra-high-strength Hydroxyapatite/poly(L-lactide) Composite Rods for Internal Fixation of Bone Fractures /
[ T.Furukawa;Y. Matsusue;T. Yasunaga;Y.Shikinami;M.Okuno;T.Nakamura ] / Biomaterials   DOI   ScienceOn
8 Attachment and Growth of Cultured Fibroblast Cekks ib PVA/Chitosan -Blended Hydrogels /
[ T.Koyano;N.Minoura;M.Nagura;K.Kobayashi ] / Biomed.Mater.Res   DOI   ScienceOn
9 Precipitation of Calcium Phosphates from Electrolyte Solutions(ⅴ)-The Influence of Citrate Ions /
[ L. Brecevie and H. F. Milhofer ] / Calcif.Tissue Int   DOI   ScienceOn
10 The Use of Calcium Hydroxyapatie Ceramie on Bone Yumor Surgery /
[ A. Uchida;N. Araki;Y.Shinto;H. Yoshikawa;K.Ono;E. Kurisaki ] / J. Bone Joint Surg