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http://dx.doi.org/10.5933/JKAPD.2017.44.1.47

A Retrospective Study of Critical Success Factors in Regenerative Endodontic Treatment  

Jeong, Hwakyong (Department of Pediatric Dentistry, School of Dentistry, Chosun University)
Lee, Nanyoung (Department of Pediatric Dentistry, School of Dentistry, Chosun University)
Lee, Sangho (Department of Pediatric Dentistry, School of Dentistry, Chosun University)
Publication Information
Journal of the korean academy of Pediatric Dentistry / v.44, no.1, 2017 , pp. 47-55 More about this Journal
Abstract
This study evaluated critical factors influencing the success of regenerative endodontic treatment for necrotic immature permanent teeth. The study enrolled patients who had regenerative endodontic treatment in a necrotic immature permanent tooth through 1-year follow-up. Possible explanatory variables related to the success rates for 46 teeth were age, gender, dental stage at the initial appointment, etiology, treatment information, and clinical and radiographic outcomes. The dental stage at the time of regenerative endodontic treatment did not influence the success rate. The success rate was significantly related to the etiology of the necrotic immature tooth. The success rate according to etiology decreased in the following order: dens evaginatus, caries, and trauma. There was also a significant difference according to the type of antimicrobial. The success rate was influenced by appropriate disinfection of the root canal system, provision of a scaffold, and coronal sealing. Above all, careful case selection is necessary for treating a necrotic immature permanent tooth, especially in cases of trauma.
Keywords
Regenerative endodontic treatment; Immature permanent teeth; Success rates;
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Times Cited By KSCI : 2  (Citation Analysis)
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1 Jeon SY, Lee NY, Lee SH : Pulp revascularization of infected immature permanent teeth using platelet-rich fibrin and double antibiotic paste : Case Report. J Korean Acad Pediatr Dent, 40:216-222, 2013.   DOI
2 Bansal R, Jain A, Mittal S : Current overview on challenges in regenerative endodontics. J Conserv Dent, 18:1-6, 2015.   DOI
3 Nosrat A, Homayounfar N, Oloomi K : Drawbacks and unfavorable outcomes of regenerative endodontic treatments of necrotic immature teeth: a literature review and report of a case. J Endod, 38:1428-1434, 2012.   DOI
4 Shah N, Logani A, Aggarwal V, et al. : Efficacy of revascularization to induce apexification/apexogensis in infected, nonvital, immature teeth: a pilot clinical study. J Endod, 34:919-925, 2008.   DOI
5 Aggarwal V, Miglani S, Singla M : Conventional apexification and revascularization induced maturogenesis of two non-vital, immature teeth in same patient: 24 months follow up of a case. J Conserv Dent, 15:68-72, 2012.   DOI
6 Huang GT : A paradigm shift in endodontic management of immature teeth: conservation of stem cells for regeneration. J Dent, 36:379-386, 2008.   DOI
7 Wigler R, Kaufman AY, Torneck CD, et al. : Revascularization : a treatment for permanent teeth with necrotic pulp and incomplete root development. J Endod, 39:319-326, 2013.   DOI
8 Trope M : Regenerative potential of dental pulp. Pediatr Dent, 30:206-210, 2008.
9 Jadhav G, Shah N, Logani A : Revascularization with and without platelet-rich plasma in nonvital, immature, anterior teeth: a pilot clinical study. J Endod, 38:1581-1587, 2012.   DOI
10 Garcia-Godoy F, Murray PE : Recommendations for using regenerative endodontic procedures in permanent immature traumatized teeth. Dent Traumatol, 28:33-41, 2012.   DOI
11 Nosrat A, Seifi A, Asgary S : Regenerative endodontic treatment (revascularization) for necrotic immature permanent molars: a review and report of two cases with a new biomaterial. J Endod, 37:562-567, 2011.   DOI
12 Alobaid AS, Cortes LM, Gibbs JL, et al. : Radiographic and clinical outcomes of the treatment of immature permanent teeth by revascularization or apexification: a pilot retrospective cohort study. J Endod, 40:1063-1070, 2014.   DOI
13 Hargreaves KM, Diogenes A, Teixeira FB : Treatment options: biological basis of regenerative endodontic procedures. Pediatr Dent, 35:129-140, 2013.
14 Law AS : Considerations for regeneration procedures. Pediatr Dent, 35:141-152, 2013.
15 Jeeruphan T, Jantarat J, Hargreaves KM, et al. : Mahidol study 1 : comparison of radiographic and survival outcomes of immature teeth treated with either regenerative endodontic or apexification methods: a retrospective study. J Endod, 38:1330-1336, 2012.   DOI
16 Chueh LH, Ho YC, Chiang CP, et al. : Regenerative endodontic treatment for necrotic immature permanent teeth. J Endod, 35:160-164, 2009.   DOI
17 Bose R, Nummikoski P, Hargreaves K : A retrospective evaluation of radiographic outcomes in immature teeth with necrotic root canal systems treated with regenerative endodontic procedures. J Endod, 35:1343-1349, 2009.   DOI
18 Lee BN, Moon JW, Hwang YC, et al. : A review of the regenerative endodontic treatment procedure. Restor Dent Endod, 40:179-187, 2015.   DOI
19 Bezgin T, Sonmez H : Review of current concepts of revascularization/revitalization. Dent Traumatol, 31:267-273, 2015.   DOI
20 Demirjian A, Goldstein H, Tanner JM : A new system of dental age assessment. Human Biol, 45:211-227, 1973.
21 Kim HN, Lee NY, Lee SH : Regenerative endodontic treatment of immature permanent teeth by using platelet-rich fibrin. J Korean Acad Pediatr Dent, 39:174-180, 2012.   DOI
22 Sato T, Hoshino E, Uematsu H, Noda T : In vitro antimicrobial susceptibility to combinations of drugs on bacteria from carious and endodontic lesions of human deciduous teeth. Oral Microbiol Immunol, 8:172-176, 1993.   DOI
23 Huang GT, Sonoyama W, Shi S, et al. : The hidden treasure in apical papilla: the potential role in pulp/dentin regeneration and bioroot engineering. J Endod, 34:645-651, 2008.   DOI
24 Priya MH, Tambakad PB, Naidu J : Pulp and periodontal regeneration of an avulsed permanent mature incisor using platelet-rich plasma after delayed replantation: a 12-month clinical case study. J Endod, 42:66-71, 2016.
25 Petrino JA, Boda KK, McClanahan SB, et al. : Challenges in regenerative endodontics: a case series. J Endod, 36:536-541, 2010.   DOI
26 Shin SY, Albert JS, Mortman RE : One step pulp revascularization treatment of an immature permanent tooth with chronic apical abscess: a case report. Int Endod J, 42:1118-1126, 2009.   DOI
27 Shabahang S : Treatment options: apexogenesis and apexification. Pediatr Dent, 35:125-128, 2013.