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http://dx.doi.org/10.5933/JKAPD.2015.42.2.197

The Scope of Regenerative Endodontics on Open-Apices in Young Permanent Teeth  

Cho, Yongbum (Department of Conservative Dentistry, School of Dentistry, Dankook University)
Publication Information
Journal of the korean academy of Pediatric Dentistry / v.42, no.2, 2015 , pp. 197-202 More about this Journal
Abstract
Numerous challenges in treating permanent dentition are encountered, especially in treating immature teeth with pulp necrosis. Historically, calcium hydroxide application during long periods of time was used to induce the formation of a calcific barrier across the open apex. In 2004, a new treatment modality for the management of the open apex was introduced. This treatment was named as 'revascularization' and gained acceptance among dentists. The protocol was different from the traditional apexification techniques in that the canal was irrigated and disinfected with a combination of three antibiotics (ciprofloxacin, metronidazole and minocycline). At the next appointment, bleeding was induced and the canal was sealed with MTA. Successful regenerative endodontic treatment of necrotic immature permanent teeth can provide continued root development, increased thickness in the dentinal walls and apical closure. These developments of a functional pulp-dentin complex have a promising impact on retaining the natural teeth, the goal of the dental health care.
Keywords
Apexification; Immature teeth; Regenerative Endodontics; Revascularization; Calcium hydroxide; MTA;
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1 Banchs F, Trope M : Revascularization of immature permanent teeth with apical periodontitis: new treatment protocol? J Endod, 30:196-200, 2004.   DOI
2 Frank AL : Therapy for the divergent pulpless tooth by continued apical formation. JADA, 72:87-93, 1966.
3 Abbot PV : Apexification with calcium hydroxidewhen should the dressing be changed? The case for regular dressing changes. Aust Endod J, 24:27-32, 1998.   DOI
4 Andreasen JO, Farik B, Munksgaard EC : Longterm calcium hydroxide as a root canal dressing may increase risk of root fracture. Dent Traumatol, 18:134-7, 2002.   DOI
5 Margelos J, Eliades G, Verdelis C, et al. : Interaction of calcium hydroxide with zinc oxide eugenol type sealers: a potential clinical problem. J Endod, 23:43-8, 1997.   DOI
6 Torabinejad M, Chivian N : Clinical applications of mineral trioxide aggregate. J Endod, 25:197-205, 1999.   DOI
7 Sarris S, Tahmessebi JF, Duggal MS, et al. : A clinical evaluation of mineral trioxide aggregate for rootend closure of non-vital immature permanent incisors in children - a pilot study. Dent Traumatol, 24:79-85, 2008.   DOI
8 Witherspoon DE, Small JC, Regan JD : Retrospective analysis of open apex teeth obturated with mineral trioxide aggregate. J Endod, 34:1171-1176, 2008.   DOI
9 American Association of Endodontics. Clinical considerations for a regenerative procedure. Available at: www.aae.org.
10 Iwaya SI, Ikawa M, Kubota M : Revascularization of an immature permanent tooth with apical periodontitis and sinus tract. Dent Traumatol, 17:185-187, 2001.   DOI
11 Murray PE, Garcia-Godoy F, Hargreaves KM : Regenerative endodontics: a review of current status and a call for action. J Endod, 33:377-390, 2007.   DOI
12 Shuping GB, Orstavik D, Sigurdsson A, et al. : Reduction of intracanal bacteria using nickel-titanium rotary instrumentation and various medications. J Endod, 26:751-755, 2000.   DOI
13 Sato T, Hoshino E, Uematsu H, et al. : In vitro antimicrobial susceptibility to combinations of drugs on bacteria from carious and endodontic lesions of human deciduous teeth. Oral Microbiol Immun, 8:172-176, 1993.   DOI
14 Kim JH, Kim Y, Shin SJ, et al. : Tooth discoloration of immature permanent incisor associated with triple antibiotic therapy: a case report. J Endod, 36:1086-1091, 2010.   DOI
15 Chuensombat S, Khemaleelakul S, Chattipakorn S, et al. : Cytotoxic effects and antibacterial efficacy of a 3-antibiotic combination: an in vitro study. J Endod; 39:813-819, 2013.   DOI
16 Haapasolo M, Shen Y, Qian W, et al. : Irrigation in endodontics. Dent Clin North Am, 54:291-312, 2010.   DOI   ScienceOn
17 Parirokh M, Torabinejad M : Mineral trioxide aggregate: a comprehensive literature review-Part I: chemical, physical and antibacterial properties. J Endod, 36:16-27, 2010.   DOI
18 Petrino JA, Boda KK, Shambarger S, et al. : Challenges in regenerative endodontics: a case series. J Endod, 36:536-541, 2010.   DOI   ScienceOn
19 Hoshino E, Kurihara-Ando N, Sato I, et al. : In-vitro antibacterial susceptibility of bacteria taken from infected root dentine to a mixture of ciprofloxacin, metronidazole and minocycline. Int Endod J, 29:125-130, 1996.   DOI