Browse > Article
http://dx.doi.org/10.5933/JKAPD.2012.39.1.43

TREATMENT OF TOOTH DISCOLORATION ASSOCIATED WITH TRIPLE ANTIBIOTIC THERAPY: CASE REPORTS  

Bak, So-Yeon (Department of Pediatric Dentistry, School of Dentistry, Seoul National University)
Kim, Young-Jae (Department of Pediatric Dentistry, School of Dentistry, Seoul National University)
Kim, Jung-Wook (Department of Pediatric Dentistry, School of Dentistry, Seoul National University)
Jan, Ki-Taeg (Department of Pediatric Dentistry, School of Dentistry, Seoul National University)
Lee, Sang-Hoon (Department of Pediatric Dentistry, School of Dentistry, Seoul National University)
Kim, Chong-Chul (Department of Pediatric Dentistry, School of Dentistry, Seoul National University)
Hahn, Se-Hyun (Department of Pediatric Dentistry, School of Dentistry, Seoul National University)
Hyun, Hong-Keun (Department of Pediatric Dentistry, School of Dentistry, Seoul National University)
Publication Information
Journal of the korean academy of Pediatric Dentistry / v.39, no.1, 2012 , pp. 43-50 More about this Journal
Abstract
The concept of revascularization of necrotic pulps regained interest and became an alternative conservative treatment option for young permanent teeth with immature roots. Revascularization of immature teeth with apical periodontitis depends mainly on disinfection of the canal. Since the infection of the root canal system is considered to be polymicrobial, a combination of drugs would be needed to treat the diverse flora. A triple antibiotic mixture of metronidazole, ciprofloxacin, and minocycline was used as an intracanal medicament. However, discoloration was developed after applying the triple antibiotic mixture. It is believed that the marked discoloration is related to the use of minocycline. The aim of this article was to present cases of coronal discoloration after triple antibiotic therapy in immature tooth and was treated with bleaching technique to control coronal discoloration. In conclusion, revascularization by using triple antibiotics promotes a paradigm shift in treating endodontically involved permanent teeth. However, we should understand that triple antibiotics containing minocycline induces tooth discoloration. Further research to prevent coronal discoloration should be investigated and suggested for the safe use of triple antibiotics.
Keywords
Triple antibiotics; Metronidazole; Minocycline; Ciprofloxacin; Crown discoloration; Bleaching;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
연도 인용수 순위
1 Trope M : Treatment of the immature tooth with a non-vital pulp and apical periodontitis. Dent Clin N Am, 54:313-324, 2010.   DOI   ScienceOn
2 Hattab FN, Qudeimat MA, Al-Rimawi HS. : Dental discoloration: An overview. J Esthet Dent, 11:291- 310, 1999.   DOI
3 Cheek CC, Heymann HO : Dental and oral discolorations associated with minocycline and other tetracycline analogs. J Esthet Dent, 11:43-48, 1999.   DOI
4 McKenna BE, Lamey PJ, Kennedy JG, et al. : Minocycline-induced staining of the adult permanent dentition: a review of the literature and report of a case. Dent Update, 26:160-162, 1999.
5 Tredwin CJ, Scully C, Began-Sebastian JV : Druginduced disorders of teeth. J Dent Res, 84:596-602, 2005.   DOI   ScienceOn
6 Kim ST, Abbott PV, McGinley P : The effects of Ledermix paste on discolouration of mature teeth. Int Endod J, 33:227-232, 2000.   DOI   ScienceOn
7 Kim JH, Kim Y, Shin SJ, et al. : Tooth Discoloration of immature permanent incisor associated with triple antibiotic therapy: A case report. J Endod, 36:1086-1091, 2010.   DOI   ScienceOn
8 권소란, 고석훈 역. : 치아미백과 심미수복. 지성출판사, 서울, 159-163, 2002.
9 Sheets CG, Paquette JM : Tooth-whitening modalities for pulpless and discolored teeth. In: Cohen S, Burns RC, eds. : Pathway of the pulp. 8th ed. : Mosby, St.Louis, Missouri, 749-764, 2002.
10 Brown G : Factors influencing successful bleaching of the discolored root-filled tooth. Oral Surg Oral Med Oral Pathol, 20:238-244, 1965.   DOI   ScienceOn
11 Reynolds K, Johnson JD, Cohenca N : Pulp revascularization of necrotic bilateral bicuspids using a modified novel technique to eliminate potential coronal discolouration: a case report. Int Endod J, 42:84- 92, 2009.   DOI   ScienceOn
12 須田英明,興地隆史, 五味博之, 林正規 :臨床歯内療法-器材.薬剤.テクニックのコンビネ-ション-. デンタルダイヤモンド社, 東京, Japan, 20-35, 2008.
13 김소정, 조해성, 정윤주 외 : 항생제를 이용한 미성숙 영구치의 치험례. 대한소아치과학회지, 38(1):44-49, 2011.
14 Huang GT : A paradigm shift in endodontic management of immature teeth: Conservation of stem cells for regeneration. J Dent, 36:379-386, 2008.   DOI   ScienceOn
15 Iwaya SI, Ikawa M, Kubota M : Revascularization of an immature permanent tooth with apical periodontitis and sinus tract. Dent Traumatol, 17:185-187, 2001.   DOI   ScienceOn
16 Banchs F, Trope M : Revascularization of immature permanent teeth with apical periodontitis: new treatment protocol?. J Endod, 30:196-200, 2004.   DOI   ScienceOn
17 윤영미, 이난영, 이상호 : 치근단 병소를 가진 영구치의 보존적 치수 치료. 대한소아치과학회지, 38(3):276-283, 2011.
18 Windley W, Teixeira F, Levin L, et al. : Disinfection of immature teeth with a triple antibiotic paste. J Endod, 31:439-443, 2005.   DOI   ScienceOn
19 Hoshino E, Kurihara-Ando N, Sato I, et al. : In-vitro antibacterial susceptibility of bacteria taken from infected root dentine to a mixture of ciprofloxacin, metronidazole and minocycline. Int Endod J, 29:125-130, 1996.   DOI
20 Sato I, Ando-Kurihara N, Hoshino E, et al. : Sterilization of infected root-canal dentine by topical application of a mixture of ciprofloxacin, metronidazole and minocycline in situ. Int Endod J, 29:118- 124, 1996.   DOI