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THE ANTIMICROBIAL EFFECT OF HORSERADISH(ARMORACIA RUSTICANA) ROOT EXTRACTS AGAINST ANAEROBES ISOLATED FROM ORAL CAVITY  

Jang, Yong-Gul (Department of Pediatric Dentistry, Oral Science Research Center, College of Dentistry)
Park, Ho-Won (Department of Pediatric Dentistry, Oral Science Research Center, College of Dentistry)
Shin, Il-Sik (Faculty of Marine Food Science and Technology, Gangneung-Wonju National University)
Lee, Ju-Hyun (Department of Pediatric Dentistry, Oral Science Research Center, College of Dentistry)
Seo, Hyun-Woo (Department of Pediatric Dentistry, Oral Science Research Center, College of Dentistry)
Publication Information
Journal of the korean academy of Pediatric Dentistry / v.37, no.2, 2010 , pp. 168-178 More about this Journal
Abstract
Objective : The aim of this study was to determine the antimicrobical effect of horseradish root extracts against Enterococcus faecalis and Fusobacterium nucleatum isolated from oral cavity compared with reference strain, and compared with that of chlorhexidine. Method : Horseradish root extracts and chlorhexidine were sequentially diluted and tested against anaerobes(E. faecalis, F. nucleatum) isolated from children's oral cavity. The microbes were anaerobically incubated and the minimum inhibitory concentration(MIC) and minimum bactericidal concentration(MBC) were detected. Results :1. Horseradish root extracts showed antimicrobial effect against E. faecalis isolated strain at same or slightly higher concentration compared with MIC of reference strain. 2. $625.0\sim1,250.0{\mu}g/ml$ horseradish root extracts showed similar antimicrobial effect with chlorhexidine($7.8\sim15.6{\mu}g/ml$). 3. Horseradish root extracts showed antimicrobial effect against F. nucleatum isolated strain at same or slightly higher concentration compared with MIC of reference strain. 4. $78.1\sim312.5{\mu}g/ml$ horseradish root extracts showed similar antimicrobial effect with chlorhexidine($7.8\sim15.6{\mu}g/ml$). Conclusions : The results of this study confirm that horseradish root extracts has antimicrobial effect against anaerobes isolated from oral cavity as well as reference strain. And we found the potential of horseradish root extracts as a canal irrigant or disinfectant.
Keywords
Horseradish(Armoracia rusticana) root extracts; Allylisothiocyanate(AIT); Anaerobes; Isolation; Chlorhexidine; Antibacterial effect;
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Times Cited By KSCI : 6  (Citation Analysis)
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