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http://dx.doi.org/10.5010/JPB.2014.41.4.169

Metabolic engineering for biofortification of lipophilic antioxidants in plants  

Kim, Eun-Ha (Department of Agricultural Biotechnology, National Academy of Agricultural Science, Rural Development Administration)
Lee, Kyeong-Ryeol (Department of Agricultural Biotechnology, National Academy of Agricultural Science, Rural Development Administration)
Kim, Jong-Bum (Department of Agricultural Biotechnology, National Academy of Agricultural Science, Rural Development Administration)
Roh, Kyung Hee (Department of Agricultural Biotechnology, National Academy of Agricultural Science, Rural Development Administration)
Kang, Han Chul (Department of Agricultural Biotechnology, National Academy of Agricultural Science, Rural Development Administration)
Kim, Hyun Uk (Department of Agricultural Biotechnology, National Academy of Agricultural Science, Rural Development Administration)
Publication Information
Journal of Plant Biotechnology / v.41, no.4, 2014 , pp. 169-179 More about this Journal
Abstract
Intracellular antioxidants include low molecular weight scavengers of oxidizing species, and enzymes which degrade superoxide and hydroperoxides. Such antioxidants systems prevent oxidative damage to cellular component by scavenging free radicals and activated oxygen species. Hydrophobic scavengers are found in cell membrane where they interrupt chain reactions of lipid peroxidation. The three major lipophilic antioxidant classes for human health are carotenoids, vitamin E and coenzyme Q10. The biofortification of staple crops with these lipid soluble antioxidants is an attractive strategy to increase the nutritional quality of human food. Here, we have summarized the biosynthetic pathways of three lipid soluble antioxidants in plants and current status of genetic engineered plants for elevated levels of each lipophilic antioxidant.
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