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http://dx.doi.org/10.5010/JPB.2007.34.4.313

Biological Effect and Chemical Composition Variation During Self-Fermentation of Stored Needle Extracts from Pinus densiflora Siebold & Zucc.  

Paudyal, Dilli P. (Department of Biotechnology and BK21 Research Team for Protein Activity Control, Chosun University)
Park, Ga-Young (Department of Biotechnology and BK21 Research Team for Protein Activity Control, Chosun University)
Hwang, In-Deok (Department of Biotechnology and BK21 Research Team for Protein Activity Control, Chosun University)
Kim, Dong-Woon (Department of Clinical Pathology, Gwangyang Health College)
Cheong, Hyeon-Sook (Department of Biotechnology and BK21 Research Team for Protein Activity Control, Chosun University)
Publication Information
Journal of Plant Biotechnology / v.34, no.4, 2007 , pp. 313-322 More about this Journal
Abstract
Extract of Japanese red pine needles has been used in Asia pacific regions since long periods believing its valuable properties as tonic and ability of curing diseases of unidentified symptoms. Some selective compounds present in the extract and their effects were analyzed. Carbohydrates and vitamin c were identified using HPLC; terpenoid compounds by GC-MS; anti-bacterial analysis by paper discs, plates count and gastrointestinal motility by whole cell patch clamp. The extract is a mixture of compounds therefore its diverse effect was expected. Self-fermentation in extract proceeds after spontaneous appearance of yeast strains without inoculation. Effects and composition of the extract vary with varying period of self-fermentation. Extract inhibits the growth of bacteria dose dependently exhibiting its antibacterial properties however effectiveness increases with increase in fermentation period. The extract also can modulate gastrointestinal motility in murine small intestine by modulating pace maker currents in ICC mediated through ATP sensitive potassium channel.
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1 Yoon SU (1997) Pine trees and natural remedy. Academy Press Inc Seoul 40-43
2 Kim EJ, Jung SW, Choi KP, Ham SS (1998) Cytotoxic effect of the pine needle extracts. Korean J Food Sci Technol 30: 213-217   과학기술학회마을
3 Ahmada R, Alib AM, Israf DA, Ismaila NH, Shaarid K, Lajis NH (2005) Antioxidant, radical scavenging, anti- inflammatory, cytotoxic and antibacterial activities of methanolic extracts of some Hedyotis species. Life Sci. 76: 1953-1964   DOI   ScienceOn
4 Blanco-Gomis D, MangasAlonso JJ, Cabrales IM, Abrodo PA (2002) Characterization of Cider Apples on the Basis of Their Fatty Acid Profiles. Agric. Food Chem 50: 1097-1100   DOI   ScienceOn
5 Esposito K, Nappo F, Giugliano F, Giugliano G, Marfella R, Giugliano D (2003) Effect of dietary antioxidants on postprandial endothelial dysfunction induced by a highfat meal in healthy subjects. Am J Clin. Nutr 77: 139-143   DOI
6 Chung HJ, Hwang GH, Yoo MJ, Rhee SJ (1996) Chemical composition of pine sprouts and pine needles for the production of pine sprout tea. Koean J Dietary and Culture 11: 635-641   과학기술학회마을
7 Chung YJ, Bae MW, Choung MI, Lee JS, Chung KS (2002) Cytotoxic effect of the distilled pine-needle extracts on several cancer cell lines in vitro. J Korean Soc Food Sci. Nutr 31: 691-695   DOI   ScienceOn
8 Dupont S, Caffin N, Bhandari B, Dykes GA (2006) In vitro antibacterial activity of Australian native herb extracts against food-related bacteria. Food Control 17: 929-932   DOI   ScienceOn
9 Hong WS (1999) The ingredients and use of medicinal herb. llwonseogak Co, Seoul 42-144
10 Ichikawa S, Takigawa H, Nara S (1998) Effects of sho-jusen, an herbal medicine, on unidentified clinical syndrome. J Clin. Pharmacol New Drugs 47: 879-887
11 Jeon HJ, Lee KS, Ahn YJ (2001) Growth-inhibiting effects of constituents of Pinus densiflora leaves on human intestinal bacteria. Food Sci Biotech 10: 403-407
12 Jerez M, Selga A, Sineiro J, Torrens JL, Nunez MJ (2007) A comparisonbetween bark extracts from Pinus pinaster and Pinus radiata: Antioxidant activity and procyanidin composition. Food Chem 100: 439-444   DOI   ScienceOn
13 Perez-Prieto LJ, Lopez-Roca JM Gomez-Plaza E (2003) Difference in major volatile compounds of red wine according to storage length and storage conditions. J Food Composition Analysis 16: 697-705   DOI   ScienceOn
14 Kim MJ, Kim YJ, Park HJ, Chung JH, Leem KH, Kim HK (2006) Apoptotic effect of red wine polyphenols on human colon cancer SNU-C4 cells. Food Chern Toxicol 44: 898-902   DOI   ScienceOn
15 Moteki H, Hibasami H, Yamada Y, Katsuzaki H, Imai K, Komiya T (2002) Specific induction of apoptosis by 1,8-cineole in two human leukemia cell lines, but not in human stomach cancer cell line. Oncology Reports 9: 757-760
16 Park G, Li H, Hwang I, Cheong H (2006) The functional effects of fermented pine needle extracts. Korean J Bioeng 21: 363-370   과학기술학회마을
17 Sanders KM (1996) A case for interstitial cells of Cajal as pacemakers and mediators of neurotransmission in the gastrointestinal tract. Gastroenterology 111: 492-515   DOI   ScienceOn
18 Thuneberg L (1982) Interstitial cells of Cajal: intestinal pacemakers. Adv. Anat. Embryol. Cell Biol 71: 1-130   DOI
19 Tokutomi N, Maeda H, Tokutomi Y, Sato D, Sugita M, Nishikawa S, Nishikawa S, Nakao J, Imamura T, Nishi K (1995) Rhythmic Cl currents and physiological roles of the intestinal c-Kit-positive cells. Pflugers Archiv 431: 169-177   DOI
20 Tribble DL (1999) Antioxidant Consumption and Risk of Coronary Heart Disease: Emphasis on Vitamin C, Vitamin E, and ${\beta}$-Carotene. Circulation 99: 591-595   DOI   ScienceOn
21 Oussalah M, Caillet S, Saucier L, Lacroix M (2006) Antimicrobial effects of selected plant essential oils on the growth of a Pseudomonas putide strain isolated from meat. Meat Sci. 73: 236-244   DOI   ScienceOn
22 Cheong HS, Paudyal DP, Jun JY, Yeum CH, Yoon PJ, Park CG, Kim MY, So I, Kim K, Choi S (2005) Effects of Pine Needle Extract on Pacemaker Currents in Interstitial Cells of Cajal from the Murine Small Intestine. Mol Cells 20: 235-240
23 Choi EJ, Lee E, Rhim TJ, Cha BC, Park HJ (1997) Antimicrobial activities of pine needle (Pinus densitlore Seib Zucc) extract. J Korean Soc Food Sci. Nutr 25: 293-297
24 Kim, YS, Shin, DH (2005) Volatile components and antibacterial effects of pine needle (Pine densiflora S. and Z.) extracts. Food microbiol 22: 37-45   DOI   ScienceOn
25 Thomsen L, Robinson TL, Lee JC, Farraway LA, Hughes MJ, Andrews DW, Huizinga JD (1998) Interstitial cells of Cajal generate a rhythmic pacemaker current. Nat Med 4: 848-851   DOI   ScienceOn
26 Petrakis PV, Roussis V, Papadimitriou D, Vaglas C, Tsitsimpikou C(2005) The effect of terpenoid extracts from 15 pine species on the feeding behavioural sequence of the late instars of the pine processionary caterpillar Thaumetopoea pityocampa. Behavioural Process 69: 303-322   DOI   ScienceOn
27 Koh SD, Sanders KM, Ward SM (1998) Spontaneous electrical rhythmicity in cultured interstitial cells of Cajal from the murine small intestine. J Physiol 513: 203-213   DOI
28 Kong Z, Liu Z, Ding B, (1995) Study on antimutagenic effect of pine needle extract. Mutat. Res 347: 101-104   DOI   ScienceOn
29 Moon JJ, Han YB, Kim JS (1993) Studies on antitumor effects of pine needles, Pinus densiDora Sieb et Zucc. Korean Vet Res 33: 701-710
30 Koukos PK, Papadopoulou KI, Patiaka DT, Papagiannopoulos AD (2000) Chemical composition of essential oils from needles and twigs of balkan pine (Pinus peuce Grisebach) grown in northern Greece. J Agric Food Chem 48: 1266-1268   DOI   ScienceOn
31 Ward SM, Burns AJ, Torihashi S, Sanders KM (1994) Mutation of the proto-oncogene c-kit blocks development of interstitial cells andintestinal electrical rhythmicity in murine mutants. J Physiol 480: 91-97   DOI
32 Watanabe T, Inaba K, Nakai A, Mitsunaga T, Ohnishi J, Koshijima T (1991) Water-soluble polysaccharides from the root of Pinus densiflora Phytochem 30: 1425-1429   DOI   ScienceOn