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http://dx.doi.org/10.22857/kjbp.2022.29.1.003

Alterations in Functions of Cognitive Emotion Regulation and Related Brain Regions in Maltreatment Victims  

Kim, Seungho (Department of Medical & Biological Engineering, Kyungpook National University)
Lee, Sang Won (Department of Psychiatry, Kyungpook National University Chilgok Hospital)
Chang, Yongmin (Department of Molecular Medicine, School of Medicine, Kyungpook National University)
Lee, Seung Jae (Department of Psychiatry, School of Medicine, Kyungpook National University)
Publication Information
Korean Journal of Biological Psychiatry / v.29, no.1, 2022 , pp. 15-21 More about this Journal
Abstract
Objectives Maltreatment experiences can alter brain function related to emotion regulation, such as cognitive reappraisal. While dysregulation of emotion is an important risk factor to mental health problems in maltreated people, studies reported alterations in brain networks related to cognitive reappraisal are still lacking. Methods Twenty-seven healthy subjects were recruited in this study. The maltreatment experiences and positive reappraisal abilities were measured using the Childhood Trauma Questionnaire-Short Form and the Cognitive Emotion Regulation Questionnaire, respectively. Twelve subjects reported one or more moderate maltreatment experiences. Subjects were re-exposed to pictures after the cognitive reappraisal task using the International Affective Picture System during fMRI scan. Results The maltreatment group reported more negative feelings on negative pictures which tried cognitive reappraisal than the no-maltreatment group (p < 0.05). Activities in the right superior marginal gyrus and right middle temporal gyrus were higher in the maltreatment group (uncorrected p < 0.001, cluster size > 20). Conclusions We found that paradoxical activities in semantic networks were shown in the victims of maltreatment. Further study might be needed to clarify these aberrant functions in semantic networks related to maltreatment experiences.
Keywords
Child abuse; Emotion regulation; Semantic network; Functional magnetic resonance imaging;
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