Browse > Article

Temperament and Character in Cannabis and Methamphetamine Abusers  

Kwon, Min (Addiction Clinic, Department of Psychiatry, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea)
Min, Jung-Ah (Department of Psychiatry, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea)
Choi, Ji-Hye (Department of Psychiatry, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea)
Kim, Dai-Jin (Addiction Clinic, Department of Psychiatry, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea)
Publication Information
Korean Journal of Biological Psychiatry / v.19, no.2, 2012 , pp. 99-105 More about this Journal
Abstract
Objectives : This study aims to identify temperament and characteristics of cannabis and methamphetamine abusers for elucidating psycho-biological variables related to certain substance abuse. Methods : A total of 320 patients who registered in the 'Hepatitis C cohorts study of intravenous drug users' between March 2006 and March 2010 participated in this study. Data on demographic variables were obtained and the Temperament and Character Inventory (TCI) and measures for nicotine dependence, alcohol dependence, depression and anxiety were assessed. After comparing TCI between cannabis, methamphetamine, and co-abusers, correlations between TCI and other clinical variables were examined. Results : The methamphetamine abuser group showed significantly higher scores in Novelty Seeking (NS2) and Harm Avoidance (HA3) in temperament than the cannabis abuser and co-abuser groups, whereas the cannabis abuser group had higher scores in purposefulness (SD2), congruent second nature (SD5), and self-directedness (SD) in character than the methamphetamine abuser group. In addition, temperaments and characters correlated with various psychiatric symptoms. Conclusions : We found the differences in temperament and characters among cannabis abusers, methamphetamine abusers. These findings might contribute to further understanding of mechanisms of cannabis and methamphetamine abuse.
Keywords
Cannabis; Methamphetamine; Substance abuse; Temperament; Character;
Citations & Related Records
연도 인용수 순위
  • Reference
1 UNDOC. World drug report. Geneva: United Nations Office on Drugs and Crime;2009.
2 Supreme Prosecutors of Republic of Korea. The white paper on drug crime. Seoul: Supreme Prosecutors of Republic of Korea;2011.
3 Lee JH, Kwon DH, Lee BD, Kim YT, Joe SH, Lee YM, et al. Different personality profiles between methamphetamine abusers with psychotic features and without psychotic features. J Korean Academy of Addiction Psychiatry 2010;14:29-35.
4 Cloninger CR, Przybeck TR, Svrakic DM. The Tridimensional Personality Questionnaire: U.S. normative data. Psychol Rep 1991;69:1047-1057.   DOI
5 Svrakic DM, Whitehead C, Przybeck TR, Cloninger CR. Differential diagnosis of personality disorders by the seven-factor model of temperament and character. Arch Gen Psychiatry 1993;50991-999.   DOI   ScienceOn
6 Konuma K, Hirai S, Kasahara M. Use and abuse of amphetamines in Japan, In: Segal DS, editor. Amphetamine and Its Analogs. San Diego: Academic Press;1994. p.459-478.
7 Cloninger CR, Svrakic DM, Przybeck TR. A psychobiological model of temperament and character. Arch Gen Psychiatry 1993;50:975-990.   DOI   ScienceOn
8 Koh SH, Lim KY, Cho SM, Chung YK. The comparison study of temperament and character in subjects with panic disorder. J Korean Neuropsychiatr Assoc 2004;43:706-711.
9 Han DH, Yoon SJ, Sung YH, Lee YS, Kee BS, Lyoo IK, et al. A preliminary study: novelty seeking, frontal executive function, and dopamine receptor (D2) TaqI A gene polymorphism in patients with methamphetamine dependence. Compr Psychiatry 2008;49:387-392.   DOI   ScienceOn
10 Hosak L, Libiger J, Cizek J, Beranek M, Cermakova E. The COMT Val158Met polymorphism is associated with novelty seeking in Czech methamphetamine abusers: preliminary results. Neuro Endocrinol Lett 2006;27:799-802.
11 Kim MY, Park JM, Yoon GI, Rue, TG, Gwon DH, Kim SG, et al. Novelty seeking in substance use disorder. J Korean Society of Biological Therapies in Psychiatry 2001;7:112-119.
12 Le Bon O, Basiaux P, Streel E, Tecco J, Hanak C, Hansenne M, et al. Personality profile and drug of choice; a multivariate analysis using Cloninger's TCI on heroin addicts, alcoholics, and a random population group. Drug Alcohol Depend 2004;73:175-182.   DOI   ScienceOn
13 Hosak L, Preiss M, Halir M, Cermakova E, Csemy L. Temperament and character inventory (TCI) personality profile in metamphetamine abusers: a controlled study. Eur Psychiatry 2004;19:193-195.   DOI   ScienceOn
14 Evren C, Evren B, Yancar C, Erkiran M. Temperament and character model of personality profile of alcohol- and drug-dependent inpatients. Compr Psychiatry 2007;48:283-288.   DOI   ScienceOn
15 Allnutt S, Wedgwood L, Wilhelm K, Butler T. Temperament, substance use and psychopathology in a prisoner population: implications for treatment. Aust N Z J Psychiatry 2008;42:969-975.   DOI   ScienceOn
16 Hur JW, Kim YK. Comparison of clinical features and personality dimensions between patients with major depressive disorder and normal control. Psychiatry Investig 2009;6:150-155.   DOI   ScienceOn
17 Cloninger CR, Svrakic DM. Integrative psychobiological approach to psychiatric assessment and treatment. Psychiatry 1997;60:120-141.
18 Jaffe JH, Ling W, Rawson RA. Stimulants: amphetamine (or amphetamine-like)-related disorders. In: Sadock BJ, Sadock VA, editors. Kaplan & Sadock's Comprehensive Textbook of Psychiatry. 8th ed. Philadelphia: Lippincott Williams & Wilkins;2005. p.1188-1200.
19 Zweben JE, Cohen JB, Christian D, Galloway GP, Salinardi M, Parent D, et al. Psychiatric symptoms in methamphetamine users. Am J Addict 2004;13:181-190.   DOI   ScienceOn
20 Bousman CA, Glatt SJ, Everall IP, Tsuang MT. Genetic association studies of methamphetamine use disorders: a systematic review and synthesis. Am J Med Genet B Neuropsychiatr Genet 2009;150B:1025-1049.   DOI   ScienceOn
21 Van Laere K, Goffin K, Bormans G, Casteels C, Mortelmans L, de Hoon J, et al. Relationship of type 1 cannabinoid receptor availability in the human brain to novelty-seeking temperament. Arch Gen Psychiatry 2009;66:196-204.   DOI   ScienceOn
22 Ujike H, Kishimoto M, Okahisa Y, Kodama M, Takaki M, Inada T, et al. Association Between 5HT1b Receptor Gene and Methamphetamine Dependence. Curr Neuropharmacol 2011;9:163-168.   DOI   ScienceOn
23 Tanda G, Pontieri FE, Di Chiara G. Cannabinoid and heroin activation of mesolimbic dopamine transmission by a common mu1 opioid receptor mechanism. Science 1997;276:2048-2050.   DOI
24 Budney AJ, Hughes JR. The cannabis withdrawal syndrome. Curr Opin Psychiatry 2006;19:233-238.   DOI   ScienceOn
25 Agrawal A, Wetherill L, Dick DM, Xuei X, Hinrichs A, Hesselbrock V, et al. Evidence for association between polymorphisms in the cannabinoid receptor 1 (CNR1) gene and cannabis dependence. Am J Med Genet B Neuropsychiatr Genet 2009;150B:736-740.   DOI   ScienceOn