Right Caudate Volumetric Differences in Young Healthy Adults with Different Dopamine DRD2/ANKK1 Taq 1a Polymorphisms
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Jeon, Yu-Jin
(Department of Psychiatry, Seoul National University College of Medicine)
Choi, Ye-Ra (Department of Psychiatry, Seoul National University College of Medicine) Kim, Ji-Hyun H. (Department of Psychiatry, Seoul National University College of Medicine) Jung, Ji-Young J. (Department of Psychiatry, Seoul National University College of Medicine) Kim, Da-Jung J. (Department of Psychiatry, Seoul National University College of Medicine) Yu, Suk-Gyeong (Department of Life Sciences, Ewha Womans University College of Natural Sciences) Im, Joo-Yeon Jamie (Department of Life Sciences, Ewha Womans University College of Natural Sciences) Lee, Jung-Hyun H. (Department of Psychiatry, Seoul National University College of Medicine) |
1 | Comings DE, Comings BG, Muhleman D, Dietz G, Shahbahrami B, Tast D, et al. The dopamine D2 receptor locus as a modifying gene in neuropsychiatric disorders. JAMA 1991;266:1793-1800. DOI ScienceOn |
2 | Noble EP. D2 dopamine receptor gene in psychiatric and neurologic disorders and its phenotypes. Am J Med Genet B Neuropsychiatr Genet 2003;116B:103-125. DOI ScienceOn |
3 | Thompson J, Thomas N, Singleton A, Piggott M, Lloyd S, Perry EK, et al. D2 dopamine receptor gene (DRD2) Taq1 A polymorphism: reduced dopamine D2 receptor binding in the human striatum associated with the A1 allele. Pharmacogenetics 1997;7:479-484. DOI ScienceOn |
4 | Pohjalainen T, Rinne JO, Nogren K, Lehikoinen P, Anttila K, Syvalahti EK, et al. The A1 allele of the human D2 dopamine receptor gene predicts low D2 receptor availability in healthy volunteers. Mol Psychiatry 1998;3:256-260. DOI ScienceOn |
5 | Jonsson EG, Nothen MM, Grunhage F, Farde L, Nakashima Y, Propping P, et al. Polymorphisms in the dopamine D2 receptor gene and their relationships to striatal dopamine receptor density of healthy volunteers. Mol Psychiatry 1999;4:290-296. DOI ScienceOn |
6 | Blum K, Braverman ER, Wu S, Cull JG, Chen TJ, Gill J, et al. Association of polymorphisms of dopamine D2 receptor (DRD2), and dopamine transporter (DAT1) genes with schizoid/avoidant behaviors (SAB). Mol Psychiatry 1997;2:239-246. DOI ScienceOn |
7 | Mukherjee J, Yang ZY, Brown T, Roemer J, Cooper M. 18F-desmethoxyfallypride: a fluorine-18 labeled radiotracer with properties similar to carbon-11 raclopride for PET imaging studies of dopamine D2 receptors. Life Sci 1996;59:669-678. DOI ScienceOn |
8 | Camps M, Cortes R, Gueye B, Probst A, Palacios JM. Dopamine receptors in human brain: autoradiographic distribution of D2 sites. Neuroscience 1989;28:275-290. DOI ScienceOn |
9 | De Keyser J, Claeys A, De Backer JP, Ebinger G, Roels F, Vauquelin G. Autoradiographic localization of D1 and D2 dopamine receptors in the human brain. Neurosci Lett 1988;91:142-147. DOI ScienceOn |
10 | Ebdrup BH, Glenthøj B, Rasmussen H, Aggernaes B, Langkilde AR, Paulson OB, et al. Hippocampal and caudate volume reductions in antipsychotic-naive first-episode schizophrenia. J Psychiatry Neurosci 2010;35:95-104. DOI ScienceOn |
11 | Keshavan MS, Rosenberg D, Sweeney JA, Pettegrew JW. Decreased caudate volume in neuroleptic-naive psychotic patients. Am J Psychiatry 1998;155:774-778. |
12 | Jayakumar PN, Venkatasubramanian G, Keshavan MS, Srinivas JS, Gangadhar BN. MRI volumetric and 31P MRS metabolic correlates of caudate nucleus in antipsychotic-naïve schizophrenia. Acta Psychiatr Scand 2006;114:346-351. DOI ScienceOn |
13 | Levitt JJ, McCarley RW, Dickey CC, Voglmaier MM, Niznikiewicz MA, Seidman LJ, et al. MRI study of caudate nucleus volume and its cognitive correlates in neuroleptic-naive patients with schizotypal personality disorder. Am J Psychiatry 2002;159:1190-1197. DOI ScienceOn |
14 | Stein JL, Hibar DP, Madsen SK, Khamis M, McMahon KL, de Zubicaray GI, et al. Discovery and replication of dopamine-related gene effects on caudate volume in young and elderly populations (N=1198) using genome-wide search. Mol Psychiatry 2011;16:927-937, 881. DOI ScienceOn |
15 | Eisenberg DT, Mackillop J, Modi M, Beauchemin J, Dang D, Lisman SA, et al. Examining impulsivity as an endophenotype using a behavioral approach: a DRD2 TaqI A and DRD4 48-bp VNTR association study. Behav Brain Funct 2007;3:2. DOI |
16 | Bartres-Faz D, Junqu C, Serra-Grabulosa JM, Lopez-Alomar A, Moya A, Bargallo N, et al. Dopamine DRD2 Taq I polymorphism associates with caudate nucleus volume and cognitive performance in memory impaired subjects. Neuroreport 2002;13:1121-1125. DOI ScienceOn |
17 | Harano M, Uchimura N, Abe H, Ishibashi M, Iida N, Yanagimoto K, et al. A polymorphism of DRD2 gene and brain atrophy in methamphetamine psychosis. Ann N Y Acad Sci 2004;1025:307-315. DOI ScienceOn |
18 | Antonini A, Leenders KL, Reist H, Thomann R, Beer HF, Locher J. Effect of age on D2 dopamine receptors in normal human brain measured by positron emission tomography and 11C-raclopride. Arch Neurol 1993;50:474-480. DOI ScienceOn |
19 | Gunning-Dixon FM, Head D, McQuain J, Acker JD, Raz N. Differential aging of the human striatum: a prospective MR imaging study. AJNR Am J Neuroradiol 1998;19:1501-1507. |
20 | Stanfield AC, McIntosh AM, Spencer MD, Philip R, Gaur S, Lawrie SM. Towards a neuroanatomy of autism: a systematic review and meta-analysis of structural magnetic resonance imaging studies. Eur Psychiatry 2008;23:289-299. DOI ScienceOn |
21 | Brey RL, Holliday SL, Saklad AR, Navarrete MG, Hermosillo-Romo D, Stallworth CL, et al. Neuropsychiatric syndromes in lupus: prevalence using standardized definitions. Neurology 2002;58:1214- 1220. DOI ScienceOn |
22 | First MB, Spitzer RL, Gibbon M, Williams JBW. User's Guide for the Structured Clinical Interview for DSM-IV Axis I Disorders, Research Version 2.0. New York: Biometrics Research Dept, New York State Psychiatric Institute;1996. |
23 | Hyler SE. Personality Diagnostic Questionnaire-4 (PDQ-4). New York: New York State Psychiatric Institute;1994. |
24 | Mueser KT, Curran PJ, McHugo GJ. Factor structure of the Brief Psychiatric Rating Scale in schizophrenia. Psychological Assessment 1997;9:194-204. |
25 | Patenaude B, Smith SM, Kennedy DN, Jenkinson M. A Bayesian model of shape and appearance for subcortical brain segmentation. Neuroimage 2011;56:907-922. DOI ScienceOn |
26 | Nam YS, Lee C. Genetic variations at the dopamine D2 receptor locus in Korean population. Korean J Genetics 1997;19:289-297. |
27 | Park HJ, Kim ST, Yoon DH, Jin SH, Lee SJ, Lee HJ, et al. The association between the DRD2 TaqI A polymorphism and smoking cessation in response to acupuncture in Koreans. J Alternative Complementary Med 2005;11:401-405. DOI ScienceOn |
28 | Madsen SK, Ho AJ, Hua X, Saharan PS, Toga AW, Jack CR Jr, et al. 3D maps localize caudate nucleus atrophy in 400 Alzheimer's disease, mild cognitive impairment, and healthy elderly subjects. Neurobiol Aging 2010;31:1312-1325. DOI ScienceOn |
29 | Hirvonen J, van Erp TG, Huttunen J, Aalto S, Nagren K, Huttunen M, et al. Increased caudate dopamine D2 receptor availability as a genetic marker for schizophrenia. Arch Gen Psychiatry 2005;62:371- 378. DOI ScienceOn |
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