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http://dx.doi.org/10.4051/ibc.2013.5.2.0005

Development of Information Biology (III)  

Tateno, Yoshio (School of New Biology, Daegu Gyeongbuk Institute of Science and Technology)
Publication Information
Interdisciplinary Bio Central / v.5, no.2, 2013 , pp. 5.1-5.3 More about this Journal
Abstract
Introduced were two biological investigations in which information biology played a significant role. In the first case independent findings in cancer research over a long period were united and organized by information biology and led to the outcome that was subject to a Nobel Prize. The outcome has revealed that the cause of human cancer is located in the genome in a dormant condition. The second case shows how to elucidate the function of an unknown DNA sequence or ORF in prokaryotes by a large - scale computer homology search and analyses. For the elucidation the International DNA Databases and a large - scale computer were two key factors.
Keywords
oncogene; proto-oncogene; PDGF; ORF; computer homology analysis;
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