Characterization of Antidiabetic Compounds from Extract of Torreya nucifera
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Kim, Ji Won
(Department of Microbiology & Immunology, Pusan National University School of Medicine)
Kim, Dong-Seob (Department of Food Science & Technology, College of National Resources & Life Science, Pusan National University) Lee, Hwasin (Department of Microbiology & Immunology, Pusan National University School of Medicine) Park, Bobae (Department of Microbiology & Immunology, Pusan National University School of Medicine) Yu, Sun-Nyoung (Department of Microbiology & Immunology, Pusan National University School of Medicine) Hwang, You-Lim (Department of Microbiology & Immunology, Pusan National University School of Medicine) Kim, Sang Hun (Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine) Ahn, Soon-Cheol (Department of Microbiology & Immunology, Pusan National University School of Medicine) |
1 | Jin, M., Shi, G., Tang, S., Qiao, W. and Duan, H. 2013. Flavonoids from Tetrastigma obtectum enhancing glucose consumption in insulin-resistance HepG2 cells via activating AMPK. Fitoterapia 90, 240-246. DOI |
2 | Mokashi, P., Khanna, A. and Pandita, N. 2017. Flavonoids from Enicostema littorale blume enhances glucose uptake of cells in insulin resistant human liver cancer (HepG2) cell line via IRS-1 /PI3K/Akt pathway. Biomed. Pharmacother. 90, 268-277. DOI |
3 | Scheen, A. 2014. Pharmacokinetics in patients with chronic liver disease and hepatic safety of incretin-based therapies for the management of type 2 diabetes mellitus. Clin. Pharmacokinet. 53, 773-785. DOI |
4 | Shulman, G. 200. Cellular mechanisms of insulin resistance. J. Clin. Invest. 106, 171-176. DOI |
5 | Thomas, G., Khunti, K., Curcin, V., Molokhia, M., Millett, C., Majeed, A. and Paul, S. 2014. Obesity paradox in people newly diagnosed with type 2 diabetes with and without prior cardiovascular disease. Diabetes Obes. Metab. 16, 317-325. DOI |
6 | Turrens, J. 2003. Mitochondrial formation of reactive oxygen species. J. Physiol. 552, 335-344. DOI |
7 | Xu, L., Fan, Q., Wang, X., Zhao, X. and Wang, L. 2016. Inhibition of autophagy increased AGE/ROS-mediated apoptosis in mesangial cells. Cell Death Dis. 7, e2445. DOI |
8 | Boonloh, K., Kukongviriyapan, U., Pannangpetch, P., Kongyingyoes, B., Senggunprai, L., Prawan, A., Thawornchinsombut, S. and Kukongviriyapan, V. 2015. Rice bran protein hydrolysates prevented interleukin-6-and high glucose- induced insulin resistance in HepG2 cells. Food Funct. 6, 566-573. DOI |
9 | Chen, L., Magliano, D. and Zimmet, P. 2012. The worldwide epidemiology of type 2 diabetes mellitus-present and future perspectives. Nat. Rev. Endocrinol. 8, 228-236. DOI |
10 | Cao, J., Li, X., Liu, Y., Leng, F., Li, X., Sun, C. and Chen, K. 2015. Bioassay-based isolation and identification of phenolics from sweet cherry that promote active glucose consumption by HepG2 cells. J. Food Sci. 80, C234-C240. DOI |
11 | Chung, B, S. and Ko, Y, S. 1978. Studies on the sterol components of Torreya nut of Korea. Yakhak Hoeji 22, 87-90. |
12 | DeFronzo, R. 1988. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM. Diabetes 37, 667-687. DOI |
13 | DeFronzo, R., Bonadonna, R. and Ferrannini, E. 1992. Pathogenesis of NIDDM: a balanced overview. Diabetes Care 15, 318-368. DOI |
14 | Dujic, T., Causevic, A., Bego, T., Malenica, M., Velija-Asimi, Z., Pearson, E. and Semiz, S. 2015. Organic cation transporter 1 variants and gastrointestinal side effects of metformin in patients with type 2 diabetes. Diabet. Med. 33, 511-514. DOI |
15 | Fridlyand, L. and Philipson, L. 2008. Oxidative reactive species in cell injury: Mechanisms in diabetes mellitus and therapeutic approaches. Ann. N. Y. Acad. Sci. 1066, 136-151. DOI |
16 | Jeon, H. S., Lee, Y. S. and Kim, N. W. 2009. The antioxidative activities of Torreya nucifera seed extracts. J. Kor. Soc. Food Sci. Nutr. 38, 1-8. DOI |
17 | Liu, T., Shi, C., Gao, R., Sun, H., Xiong, X., Ding, L., Chen, Q., Li, Y., Wang, J., Kang, Y. and Zhu, G. 2015. Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes. Clin. Sci. 129, 839-850. DOI |
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