1 |
Mogi, M., Harada, M., Kondo, T., Riederer, P., Inagaki, H., Minami, M. and Nagatsu, T. 1994. Interleukin-1 beta, Interleukin-6, Epidermal Growth Factor and Transforming Growth Factor-alpha are elevated in the brain from Parkinsonian patients. Neurosci. Lett. 180, 147-150.
DOI
|
2 |
Mortimer, L., Moreau, F., MacDonald, J. A. and Chadee, K. 2016. NLRP3 inflammasome inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations. Nat. Immunol. 17, 1176-1186.
DOI
|
3 |
Munoz-Planillo, R., Kuffa, P., Martinez-Colon, G., Smith, B. L., Rajendiran, T. M. and Nunez, G. 2013. K+ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter. Immunity 38, 1142-1153.
DOI
|
4 |
Murakami, T., Ockinger, J., Yu, J., Byles, V., McColl, A., Hofer, A. M. and Horng, T. 2012. Critical role for calcium mobilization in activation of the NLRP3 inflammasome. Proc. Natl. Acad. Sci. USA. 109, 11282-11287.
DOI
|
5 |
Orlowski, G. M., Colbert, J. D., Sharma, S., Bogyo, M., Robertson, S. A. and Rock, K. L. 2015. Multiple cathepsins promote pro-IL-1β synthesis and NLRP3-mediated IL-1β activation. J. Immunol. 195, 1685-1697.
DOI
|
6 |
Alcocer-Gomez, E., de Miguel, M., Casas-Barquero, N., Nunez-Vasco, J., Sanchez-Alcazar, J. A., Fernandez-Rodriguez, A. and Cordero, M. D. 2014. NLRP3 inflammasome is activated in mononuclear blood cells from patients with major depressive disorder. Brain Behav. Immun. 36, 111-117.
DOI
|
7 |
Barry, R., John, S. W., Liccardi, G., Tenev, T., Jaco, I., Chen, C. H., Choi, J., Kasperkiewicz, P., Fernandes-Alnemri, T., Alnemri, E., Drag, M., Chen, Y. and Meier, P. 2018. Sumo-mediated regulation of NLRP3 modulates inflammasome activity. Nat. Commun. 9, 3001.
DOI
|
8 |
Benedicte, F. Py., Kim, M. S., Vakifahmetoglu-Norberg, H. and Yuan, J. 2013. Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity. Mol. Cell 49, 331-338.
DOI
|
9 |
Gustot, A., Gallea, J. I., Sarroukh, R., Celej, M. S., Ruysschaert, J. M. and Raussens, V. 2015. Amyloid fibrils are the molecular trigger of inflammation in Parkinson's disease. Biochem. J. 471, 323-333.
DOI
|
10 |
Gustin, A., Kirchmeyer, M., Koncina, E., Felten, P., Losciuto, S., Heurtaux, T., Tardivel, A., Heuschling, P. and Dostert, C. 2015. NLRP3 inflammasome is expressed and functional in mouse brain microglia but not in astrocytes. PLoS One 10, e0130624.
DOI
|
11 |
Halle, A., Hornung, V., Petzold, G. C., Stewart, C. R., Monks, B. G., Reinheckel, T., Fitzgerald, K. A., Latz, E., Moore, K. J. and Golenbock, D. T. 2008. The NLRP3 inflammasome is involved in the innate immune response to amyloid-β. Nat. Immunol. 9, 857-865.
DOI
|
12 |
He, Y., Zeng, M. Y., Yang, D., Motro, B. and Nunez, G. 2016. NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux. Nature 530, 354-357.
DOI
|
13 |
Humphries, F., Bergin, R., Jackson, R., Delagic, N., Wang, B., Yang, S., Dubois, A. V., Ingram, R. J. and Moynagh, P. N. 2018. The E3 ubiquitin ligase pellino2 mediates priming of the NLRP3 inflammasome. Nat. Commun. 9, 1560.
DOI
|
14 |
Heneka, M. T., Kummer, M. P., Stutz, A., Delekate, A., Schwartz, S., Vieira-Saecker, A., Griep, A., Axt, D., Remus, A., Tzeng, T. C., Gelpi, E., Halle, A., Korte, M., Latz, E. and Golenbock, D. T. 2013. NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice. Nature 493, 674-678.
DOI
|
15 |
Hernandez-Cuellar, E., Tsuchiya, K., Hara, H., Fang, R., Sakai, S., Kawamura, I., Akira, S. and Mitsuyama, M. 2012. Cutting edge: Nitric oxide inhibits the NLRP3 inflammasome. J. Immunol. 189, 5113-5117.
DOI
|
16 |
Hornung, V., Bauernfeind, F., Halle, A., Samstad, E. O., Kono, H., Rock, K. L., Fitzgerald, K. A. and Latz, E. 2008. Silica crystals and aluminum salts activate the NLRP3 inflammasome through phagosomal destabilization. Nat. Immunol. 9, 847-856.
DOI
|
17 |
Shimada, K., Crother, T. R., Karlin, J., Dagvadorj, J., Chiba, N., Chen, S., Ramanujan, V. K., Wolf, A. J., Vergnes, L., Ojcius, D. M., Rentsendorj, A., Vargas, M., Guerrero, C., Wang, Y., Fitzgerald, K. A., Underhill, D. M., Town, T. and Arditi, M. 2012. Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity 36, 401-414.
DOI
|
18 |
Segovia, J. A., Chang, T. H., Winter, V. T., Coalson, J. J., Cagle, M. P., Pandranki, L., Bose, S., Baseman, J. B. and Kannan, T. R. 2017. NLRP3 is a critical regulator of inflammation and innate immune cell response during mycoplasma pneumoniae infection. Infect. Immun. 86, e00548-17.
|
19 |
Shaw, P. J., Lukens, J. R., Burns, S., Chi, H., McGargill, M. A. and Kanneganti, T. D. 2010. Cutting edge: Critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis. J. Immunol. 184, 4610-4614.
DOI
|
20 |
Shi, H., Wang, Y., Li, X., Zhan, X., Tang, M., Fina, M., Su, L., Pratt, D., Bu, C. H., Hildebrand, S., Lyon, S., Scott, L., Quan, J., Sun, Q., Russell, J., Arnett, S., Jurek, P., Chen, D., Kravchenko, V. V., Mathison, J. C., Moresco, E. M. Y., Monson, N. L., Ulevitch, R. J. and Beutler, B. 2016. NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component. Nat. Immunol. 17, 250-258.
DOI
|
21 |
Slusarczyk, J., Trojan, E., Wydra, K., Glombik, K., Chamera, K., Kucharczyk, M., Budziszewska, B., Kubera, M., Lason, W., Filip, M. and Basta-Kaim, A. 2016. Beneficial impact of intracerebroventricular fractalkine administration on behavioral and biochemical changes induced by prenatal stress in adult rats: Possible role of NLRP3 inflammasome pathway. Biochem. Pharmacol. 113, 45-56.
DOI
|
22 |
Yan, Y., Jiang, W., Liu, L., Wang, X., Ding, C., Tian, Z. and Zhou, R. 2015. Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome. Cell 160, 62-73.
DOI
|
23 |
Voet, S., Srinivasan, S., Lamkanfi, M. and Van Loo, G. 2019. Inflammasomes in neuroinflammatory and neurodegenerative diseases. EMBO Mol. Med. 11, e10248.
DOI
|
24 |
Wang, W., Nguyen, L. T. T., Burlak, C., Chegini, F., Guo, F., Chataway, T., Ju, S., Fisher, O. S., Miller, D. W., Datta, D., Wu, F., Wu, C. X., Landeru, A., Wells, J. A., Cookson, M. R., Boxer, M. B., Thomas, C. J., Gai, W. P., Ringe, D., Petsko, G. A. and Hoang, Q. Q. 2016. Caspase-1 causes truncation and aggregation of the Parkinson's disease-associated protein α-synuclein. Proc. Natl. Acad. Sci. USA. 113, 9587-9592.
DOI
|
25 |
Xing, Y., Yao, X., Li, H., Xue, G., Guo, Q., Yang, G., An, L., Zhang, Y. and Meng, G. 2017. Cutting edge: TRAF6 mediates TLR/IL-1R signaling-induced nontranscriptional priming of the NLRP3 inflammasome. J. Immunol. 199, 1561-1566.
DOI
|
26 |
Yang, F., Wang, Z., Wei, X., Han, H., Meng, X., Zhang, Y., Shi, W., Li, F., Xin, T., Pang, Q. and Yi, F. 2014. NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke. J. Cereb. Blood Flow Metab. 34, 660-667.
DOI
|
27 |
Yang, Z., Zhong, L., Xian, R. and Yuan, B. 2015. MicroRNA-223 regulates inflammation and brain injury via feedback to NLRP3 inflammasome after intracerebral hemorrhage. Mol. Immunol. 65, 267-276.
DOI
|
28 |
Yatsiv, I., Morganti-Kossmann, M. C., Perez, D., Dinarello, C. A., Novick, D., Rubinstein, M., Otto, V. I., Rancan, M., Kossmann, T., Redaelli, C. A., Trentz, O., Shohami, E. and Stahel, P. F. 2002. Elevated intracranial IL-18 in humans and mice after traumatic brain injury and evidence of neuroprotective effects of IL-18-binding protein after experimental closed head injury. J. Cereb. Blood Flow Metab. 22, 971-978.
DOI
|
29 |
Bruchard, M., Mignot, G., Derangere, V., Chalmin, F., Chevriaux, A., Vegran, F., Boireau, W., Simon, B., Ryffel, B., Connat, J. L., Kanellopoulos, J., Martin, F., Rebe, C., Apetoh, L. and Ghiringhelli, F. 2013. Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the NLRP3 inflammasome and promotes tumor growth. Nat. Med. 19, 57-64.
DOI
|
30 |
Boucher, D., Monteleone, M., Coll, R. C., Chen, K. W., Ross, C. M., Teo, J. L., Gomez, G. A., Holley, C. L., Bierschenk, D., Stacey, K. J., Yap, A. S., Bezbradica, J. S. and Schroder, K. 2018. Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity. J. Exp. Med. 215, 827-840.
DOI
|
31 |
Cai, X., Chen, J., Xu, H., Liu, S., Jiang, Q. X., Halfmann, R. and Chen, Z. J. 2014. Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation. Cell 156, 1207-1222.
DOI
|
32 |
Clausen, F., Hanell, A., Bjork, M., Hillered, L., Mir, A. K., Gram, H. and Marklund, N. 2009. Neutralization of interleukin-1beta modifies the inflammatory response and improves histological and cognitive outcome following traumatic brain injury in mice. Eur. J. Neurosci. 30, 385-396.
DOI
|
33 |
Codolo, G., Plotegher, N., Pozzobon, T., Brucale, M., Tessari, I., Bubacco, L. and de Bernard, M. 2013. Triggering of inflammasome by aggregated α-synuclein, an inflammatory response in synucleinopathies. PLoS One 8, e55375.
DOI
|
34 |
Franchi, L., Eigenbrod, T., Munoz-Planillo, R., Ozkurede, U., Kim, Y. G., Arindam, C., Gale Jr, M., Silverman, R. H., Colonna, M., Akira, S. and Nunez, G. 2014. Cytosolic double-stranded RNA activates the NLRP3 inflammasome via MAVS-induced membrane permeabilization and K+ efflux. J. Immunol. 193, 4214-4222.
DOI
|
35 |
Dong, Y., Fan, C., Hu, W., Jiang, S., Ma, Z., Yan, X., Deng, C., Di, S., Xin, Z., Wu, G., Yang, Y., Reiter, R. J. and Liang, G. 2016. Melatonin attenuated early brain injury induced by subarachnoid hemorrhage via regulating NLRP3 inflammasome and apoptosis signaling. J. Pineal Res. 60, 253-262.
DOI
|
36 |
Freeman, L., Guo, H., David, C. N., Brickey, W. J., Jha, S. and Ting, J. P. 2017. NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes. J. Exp. Med. 214, 1351-1370.
DOI
|
37 |
Goedert, M. and Spillantini, M. G. 2006. A century of Alzheimer's disease. Science 314, 777-781.
DOI
|
38 |
Gris, D., Ye, Z., Iocca, H. A., Wen, H., Craven, R. R., Gris, P., Huang, M., Schneider, M., Miller, S. D. and Ting, J. P. 2010. NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses. J. Immunol. 185, 974-981.
DOI
|
39 |
Fann, D. Y., Lee, S. Y., Manzanero, S., Tang, S. C., Gelderblom, M., Chunduri, P., Bernreuther, C., Glatzel, M., Cheng, Y. L., Thundyil, J., Widiapradja, A., Lok, K. Z., Foo, S. L., Wang, Y. C., Li, Y. I., Drummond, G. R., Basta, M., Magnus, T., Jo, D. G., Mattson, M. P., Sobey, C. G. and Arumugam, T. V. 2013. Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke. Cell Death Dis. 4, e790.
DOI
|
40 |
Ferrari, C. C., Pott Godoy, M. C., Tarelli, R., Chertoff, M., Depino, A. M. and Pitossi, F. J. 2006. Progressive neuro-degeneration and motor disabilities induced by chronic expression of IL-1beta in the substantia nigra. Neurobiol. Dis. 24, 183-193.
DOI
|
41 |
Franchi, L., Eigenbrod, T. and Nunez, G. 2009. Cutting edge: TNF-α mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation. J. Immunol. 183, 792-796.
DOI
|
42 |
Przedborski, S. 2017. The two-century journey of Parkinson disease research. Nat. Rev. Neurosci. 18, 251-259.
DOI
|
43 |
Pan, Y., Chen, X. Y., Zhang, Q. Y. and Kong, L. D. 2014. Microglial NLRP3 inflammasome activation mediates IL-1β-related inflammation in prefrontal cortex of depressive rats. Brain. Behav. Immun. 41, 90-100.
DOI
|
44 |
Perregaux, D. and Gabel, C. A. 1994. Interleukin-1 beta maturation and release in response to atp and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity. J. Biol. Chem. 269, 15195-15203.
DOI
|
45 |
Piancone, F., Saresella, M., Marventano, I., La Rosa, F., Santangelo, M. A., Caputo, D., Mendozzi, L., Rovaris, M. and Clerici, M. 2018. Monosodium urate crystals activate the inflammasome in primary progressive multiple sclerosis. Front. Immunol. 9, 983.
DOI
|
46 |
Qin, X. Y., Zhang, S. P., Cao, C., Loh, Y. P. and Cheng, Y. 2016. Aberrations in peripheral inflammatory cytokine levels in Parkinson disease. JAMA Neurol. 73, 1316.
DOI
|
47 |
Saresella, M., La Rosa, F., Piancone, F., Zoppis, M., Marventano, I., Calabrese, E., Rainone, V., Nemni, R., Mancuso, R. and Clerici, M. 2016. The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease. Mol. Neurodegener. 11, 23.
DOI
|
48 |
Scheiblich, H., Trombly, M., Ramirez, A. and Heneka, M. T. 2020. Neuroimmune connections in aging and neurodegenerative diseases. Trends Immunol. 41, 300-312.
DOI
|
49 |
Schmid-Burgk, J. L., Chauhan, D., Schmidt, T., Ebert, T. S., Reinhardt, J., Endl, E. and Hornung, V. 2016. A genomewide CRISPR (clustered regularly interspaced short palindromic repeats) screen identifies NEK7 as an essential component of NLRP3 inflammasome activation. J. Biol. Chem. 291, 103-109.
DOI
|
50 |
Song, N., Liu, Z. S., Xue, W., Bai, Z. F., Wang, Q. Y., Dai, J., Liu, X., Huang, Y. J., Cai, H., Zhan, X. Y., Han, Q. Y., Wang, H., Chen, Y., Li, H. Y., Li, A. L., Zhang, X. M., Zhou, T. and Li, T. 2017. NLRP3 phosphorylation is an essential priming event for inflammasome activation. Mol. Cell 68, 185-197. e186.
DOI
|
51 |
Spalinger, M. R., Kasper, S., Gottier, C., Lang, S., Atrott, K., Vavricka, S. R., Scharl, S., Raselli, T., Frey-Wagner, I., Gutte, P. M., Grutter, M. G., Beer, H. D., Contassot, E., Chan, A. C., Dai, X., Rawlings, D. J., Mair, F., Becher, B., Falk, W., Fried, M., Rogler, G. and Scharl, M. 2016. NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22. J. Clin. Invest. 126, 4388-4388.
DOI
|
52 |
Stutz, A., Kolbe, C. C., Stahl, R., Horvath, G. L., Franklin, B. S., Van Ray, O., Brinkschulte, R., Geyer, M., Meissner, F. and Latz, E. 2017. NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain. J. Exp. Med. 214, 1725-1736.
DOI
|
53 |
Swanson, K. V., Deng, M. and Ting, J. P. Y. 2019. The NLRP3 inflammasome: Molecular activation and regulation to therapeutics. Nat. Rev. Immunol. 19, 477-489.
DOI
|
54 |
Tsai, S. J. 2017. Effects of interleukin-1beta polymorphisms on brain function and behavior in healthy and psychiatric disease conditions. Cytokine Growth Factor Rev. 37, 89-97.
DOI
|
55 |
Tsuchiya, K. 2020. Inflammasome associated cell death: Pyroptosis, apoptosis, and physiological implications. Microbiol. Immunol. 64, 252-269.
DOI
|
56 |
Venegas, C., Kumar, S., Franklin, B. S., Dierkes, T., Brinkschulte, R., Tejera, D., Vieira-Saecker, A., Schwartz, S., Santarelli, F., Kummer, M. P., Griep, A., Gelpi, E., Beilharz, M., Riedel, D., Golenbock, D. T., Geyer, M., Walter, J., Latz, E. and Heneka, M. T. 2017. Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer's disease. Nature 552, 355-361.
DOI
|
57 |
Zhang, Z., Meszaros, G., He, W. T., Xu, Y., de Fatima Magliarelli, H., Mailly, L., Mihlan, M., Liu, Y., Puig Gamez, M., Goginashvili, A., Pasquier, A., Bielska, O., Neven, B., Quartier, P., Aebersold, R., Baumert, T. F., Georgel, P., Han, J. and Ricci, R. 2017. Protein kinase D at the Golgi controls NLRP3 inflammasome activation. J. Exp. Med. 214, 2671-2693.
DOI
|
58 |
Zhang, S., Tang, M. B., Luo, H. Y., Shi, C. H. and Xu, Y. M. 2017. Necroptosis in neurodegenerative diseases: A potential therapeutic target. Cell Death Dis. 8, e2905-e2905.
DOI
|
59 |
Zhang, Y., Liu, L., Liu, Y. Z., Shen, X. L., Wu, T. Y., Zhang, T., Wang, W., Wang, Y. X. and Jiang, C. L. 2015. NLRP3 inflammasome mediates chronic mild stress-induced depression in mice via neuroinflammation. Int. J. Neuropsychopharmacol. 18, pyv006.
DOI
|
60 |
Zhang, Y., Liu, L., Peng, Y. L., Liu, Y. Z., Wu, T. Y., Shen, X. L., Zhou, J. R., Sun, D. Y., Huang, A. J., Wang, X., Wang, Y. X. and Jiang, C. L. 2014. Involvement of inflammasome activation in lipopolysaccharide-induced mice depressivelike behaviors. CNS Neurosci. Ther. 20, 119-124.
DOI
|
61 |
Zheng, D., Liwinski, T. and Elinav, E. 2020. Inflammasome activation and regulation: Toward a better understanding of complex mechanisms. Cell Discov. 6, 36.
|
62 |
Zhou, R., Yazdi, A. S., Menu, P. and Tschopp, J. 2011. A role for mitochondria in NLRP3 inflammasome activation. Nature 469, 221-225.
DOI
|
63 |
Jo, W. K., Zhang, Y., Emrich, H. M. and Dietrich, D. E. 2015. Glia in the cytokine-mediated onset of depression: Fine tuning the immune response. Front. Cell. Neurosci. 9, 268.
|
64 |
Hung, W. L., Ho, C. T. and Pan, M. H. 2020. Targeting the NLRP3 inflammasome in neuroinflammation: Health promoting effects of dietary phytochemicals in neurological disorders. Mol. Nutr. Food Res. 64, 1900550.
DOI
|
65 |
Irrera, N., Pizzino, G., Calo, M., Pallio, G., Mannino, F., Fama, F., Arcoraci, V., Fodale, V., David, A., Francesca, C., Minutoli, L., Mazzon, E., Bramanti, P., Squadrito, F., Altavilla, D. and Bitto, A. 2017. Lack of the NLRP3 inflammasome improves mice recovery following traumatic brain injury. Front. Pharmacol. 8, 8459.
|
66 |
Italiani, P., Carlesi, C., Giungato, P., Puxeddu, I., Borroni, B., Bossu, P., Migliorini, P., Siciliano, G. and Boraschi, D. 2014. Evaluating the levels of interleukin-1 family cytokines in sporadic amyotrophic lateral sclerosis. J. Neuroinflammation 11, 94.
DOI
|
67 |
Iyer, S. S., He, Q., Janczy, J. R., Elliott, E. I., Zhong, Z., Olivier, A. K., Sadler, J. J., Knepper-Adrian, V., Han, R., Qiao, L., Eisenbarth, S. C., Nauseef, W. M., Cassel, S. L. and Sutterwala, F. S. 2013. Mitochondrial cardiolipin is required for NLRP3 inflammasome activation. Immunity 39, 311-323.
DOI
|
68 |
Jha, S., Srivastava, S. Y., Brickey, W. J., Iocca, H., Toews, A., Morrison, J. P., Chen, V. S., Gris, D., Matsushima, G. K. and Ting, J. P. 2010. The inflammasome sensor, NLRP3, regulates CNS inflammation and demyelination via caspase-1 and interleukin-18. J. Neurosci. 30, 15811-15820.
DOI
|
69 |
Juliana, C., Fernandes-Alnemri, T., Kang, S., Farias, A., Qin, F. and Alnemri, E. S. 2012. Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation. J. Biol. Chem. 287, 36617-36622.
DOI
|
70 |
Keane, R. W., Dietrich, W. D. and De Rivero Vaccari, J. P. 2018. Inflammasome proteins as biomarkers of multiple sclerosis. Front. Neurol. 9, 135.
DOI
|
71 |
Losy, J. and Niezgoda, A. 2001. IL-18 in patients with multiple sclerosis. Acta. Neurol. Scand. 104, 171-173.
DOI
|
72 |
Li, X., Jiao, F., Hong, J., Yang, F., Wang, L. and Gong, Z. 2020. Senp7 knockdown inhibited pyroptosis and NF-κB/NLRP3 inflammasome pathway activation in RAW 264.7 cells. Sci. Rep. 10, 16265.
DOI
|
73 |
Liu, H. D., Li, W., Chen, Z. R., Hu, Y. C., Zhang, D. D., Shen, W., Zhou, M. L., Zhu, L. and Hang, C. H. 2013. Expression of the NLRP3 inflammasome in cerebral cortex after traumatic brain injury in a rat model. Neurochem. Res. 38, 2072-2083.
DOI
|
74 |
Lopez-Castejon, G., Luheshi, N. M., Compan, V., High, S., Whitehead, R. C., Flitsch, S., Kirov, A., Prudovsky, I., Swanton, E. and Brough, D. 2013. Deubiquitinases regulate the activity of caspase-1 and interleukin-1β secretion via assembly of the inflammasome. J. Biol. Chem. 288, 2721-2733.
DOI
|
75 |
Lu, A., Magupali, V. G., Ruan, J., Yin, Q., Atianand, M. K., Vos, M. R., Schroder, G. F., Fitzgerald, K. A., Wu, H. and Egelman, E. H. 2014. Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes. Cell 156, 1193-1206.
DOI
|
76 |
Lu, M., Yang, J. Z., Geng, F., Ding, J. H. and Hu, G. 2014. Iptakalim confers an antidepressant effect in a chronic mild stress model of depression through regulating neuro-inflammation and neurogenesis. Int. J. Neuropsychopharmacol. 17, 1501-1510.
DOI
|
77 |
Maas, A. I., Stocchetti, N. and Bullock, R. 2008. Moderate and severe traumatic brain injury in adults. Lancet Neurol. 7, 728-741.
DOI
|
78 |
Kim, H. K., Andreazza, A. C., Elmi, N., Chen, W. and Young, L. T. 2016. NOD-like receptor pyrin containing 3 (NLRP3) in the post-mortem frontal cortex from patients with bipolar disorder: A potential mediator between mitochondria and immune-activation. J. Psychiatr. Res. 72, 43-50.
DOI
|
79 |
Kumar, A. and Loane, D. J. 2012. Neuroinflammation after traumatic brain injury: Opportunities for therapeutic intervention. Brain Behav. Immun. 26, 1191-1201.
DOI
|
80 |
Ma, Q., Chen, S., Hu, Q., Feng, H., Zhang, J. H. and Tang, J. 2014. NLRP3 inflammasome contributes to inflammation after intracerebral hemorrhage. Ann. Neurol. 75, 209-219.
DOI
|
81 |
Mishra, B. B., Rathinam, V. A. K., Martens, G. W., Martinot, A. J., Kornfeld, H., Fitzgerald, K. A. and Sassetti, C. M. 2013. Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1β. Nat. Immunol. 14, 52-60.
DOI
|