Characterization of Myostatin Gene Variants in Jeju Horses
![]() |
Choi, Jae-Young
(Subtropical Livestock Research Institute, National Institute of Animal Science)
Shin, Kwang-Yun (Jeju Special Self-Governing Province Livestock Promotion Agency) Lee, Jongan (Subtropical Livestock Research Institute, National Institute of Animal Science) Shin, Sang-Min (Subtropical Livestock Research Institute, National Institute of Animal Science) Kang, Yong-Jun (Subtropical Livestock Research Institute, National Institute of Animal Science) Shin, Moon-Cheol (Subtropical Livestock Research Institute, National Institute of Animal Science) Cho, In-Cheol (Subtropical Livestock Research Institute, National Institute of Animal Science) Yang, Byoung-Chul (Subtropical Livestock Research Institute, National Institute of Animal Science) Kim, Nam-Young (Planning and Coordination Division, National Institute of Animal Science, RDA) |
1 | Tozaki, T., Sato, F., Hill, E. W., Miyake, T., Endo, Y., Kakoi, H., Gawahara, H., Hirota, K. I., Nakano, Y., Nambo, Y. and Kurosawa, M. 2011. Sequence variants at the myostatin gene locus influence the body composition of Thoroughbred horses. J. Vet. Med. Sci. 73, 1617-1624. DOI |
2 | Binns, M., Boehler, D. and Lambert, D. 2010. Identification of the myostatin locus (MSTN) as having a major effect on optimum racing distance in the Thoroughbred horse in the USA. Anim. Genet. 41, 154-158. DOI |
3 | Do, K. T., Lee, J. H., Lee, H. K., Kim, J. and Park, K. D. 2014. Estimation of effective population size using single-nucleotide polymorphism (SNP) data in Jeju horse. J. Anim. 56, 1-6. |
4 | Hill, E. W., Gu, J., Eivers, S. S., Fonseca, R. G., McGivney, B. A., Govindarajan, P., Orr, N., Katz, L. M. and MacHugh, D. 2010. A sequence polymorphism in MSTN predicts sprinting ability and racing stamina in thoroughbred horses. PloS One 5, e8645. DOI |
5 | Hill, E. W., McGivney, B. A., Gu, J., Whiston, R. and Mac Hugh, D. E. 2010. A genome-wide SNP-association study confirms a sequence variant (g. 66493737C> T) in the equine myostatin (MSTN) gene as the most powerful predictor of optimum racing distance for Thoroughbred racehorses. BMC Genomics 1-10. |
6 | Nam, D. 1969. Horse production in Cheju during Lee dynasty. Studies on Korean History 4, 131-131. |
7 | Pereira, G. L., de Matteis, R., Regitano, L. C., Chardulo, L. A. L. and Curi, R. A. 2016. MSTN, CKM, and DMRT3 gene variants in different lines of Quarter Horses. J. Equine Vet. Sci. 39, 33-37. DOI |
8 | Pira, E., Vacca, G. M., Dettori, M. L., Piras, G., Moro, M., Paschino, P. and Pazzola, M. 2021. Polymorphisms at myostatin gene (MSTN) and the associations with sport performances in Anglo-Arabian racehorses. Animals 11, 964. DOI |
9 | Khummuang, S., Lee, H. G., Joo, S. S., Park, J. W., Choi, J. Y., Oh, J. H., Kim, K. H., Youn, H. H., Kim, M. and Cho, B. W. 2020. Comparison for immunophysiological responses of Jeju and Thoroughbred horses after exercise. Asian-Australas. J. Anim. Sci. 33, 424. DOI |
10 | Mosher, D. S., Quignon, P., Bustamante, C. D., Sutter, N. B., Mellersh, C. S., Parker, H. G. and Ostrander, E. A. 2007. A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs. PLoS Genet. 3, e79. DOI |
11 | Padilha, F. G. F., El Jaick, K. B., de CASTRO, L., Moreira, A. D. S. and Ferreira, A. M. R. 2018. Effect of selection for eventing on the MSTN gene in Brazilian sport horses. J. Equine Sci. 29, 21-24. DOI |
12 | Park, B. Y., Cho, S. H., Kim, J. H., Seong, P. N., Kang, G. H., Jeong, D. W., Kim, C. W., Park, H. C., Jeong, J. H. and Choi, J. S. 2010. Comparison of pork quality by different berkshire line. Food Sci. Anim. Resour. 30, 867-871. DOI |
13 | Petersen, J. L., Mickelson, J. R., Rendahl, A. K., Valberg, S. J., Andersson, L. S., Axelsson, J., Bailey, E., Bannasch, D., Binns, M. M. and Borges, A. S. 2013. Genome-wide analysis reveals selection for important traits in domestic horse breeds. PLoS Genet. 9, e1003211. DOI |
14 | Petersen, J. L., Valberg, S. J., Mickelson, J. R. and McCue, M. E. 2014. Haplotype diversity in the equine myostatin gene with focus on variants associated with race distance propensity and muscle fiber type proportions. Anim. Genet. 45, 827-835. DOI |
15 | Polasik, D., Pikula, R., Gawlik, J., Ochman, J. and Terman, A. 2015. Analysis of the myostatin gene (MSTN) polymorphism in four breeds of horses. Folia Pomer. Univ. Technol. Stetin., Agric. Aliment. Pisc. Zootech. 35, 81-86. |
16 | Stefaniuk, M., Kaczor, U. and Kulisa, M. 2014. MSTN gene polymorphism in livestock animals. Postepy Hig. Med. Dosw. (Online) 68, 633-639. DOI |
17 | Amthor, H., Macharia, R., Navarrete, R., Schuelke, M., Brown, S. C., Otto, A., Voit, T., Muntoni, F., Vrbova, G. and Partridge, T. 2007. Lack of myostatin results in excessive muscle growth but impaired force generation. Proc. Natl. Acad. Sci. USA. 104, 1835-1840. DOI |
18 | Hill, E. W., Gu, J., McGivney, B. A. and MacHugh, D. E. 2010. Targets of selection in the Thoroughbred genome contain exercise relevant gene SNPs associated with elite racecourse performance. Anim. Genet. 41, 56-63. DOI |
![]() |