Optimization of the Conditions of Flavonoid Extraction From Tartary Buckwheat Sprout Using Response Surface Methodology
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Shin, Jiyoung
(Department of Food Science & Technology, Pukyoung National University)
Choi, Iseul (Department of Food Science & Technology, Pukyoung National University) Hwang, Jinwoo (Department of Food Science & Technology, Pukyoung National University) Yang, Junho (Department of Food Science & Technology, Pukyoung National University) Lee, Yoonhyeong (Department of Food Science & Technology, Pukyoung National University) Kim, So-i (Department of Food Science & Technology, Pukyoung National University) Cha, Eunji (Department of Food Science & Technology, Pukyoung National University) Yang, Ji-Young (Department of Food Science & Technology, Pukyoung National University) |
1 | Chua, L. S. 2013. A review on plant-based rutin extraction methods and its pharmacological activities. J. Ethnopharmacol. 150, 805-817. DOI |
2 | Chobot, V. and Hadacek, F. 2011. Exploration of pro-oxidant and antioxidant activities of the flavonoid myricetin. Redox. Report 16, 242-247. DOI |
3 | Kang, J. A., Yoon, S. H., Rho, J. K., Choi, D. S., Jang, B. S. and Park, S. H. 2015. Radioprotective effect of post-treatment with rutin on γ-irradiation-induced cellular damage in mice. Kor. J. Food Sci. Technol. 47, 388-393. DOI |
4 | Kim, S. J., Zaidul, I. S. M., Suzuki, T., Mukasa, Y., Hashimoto, N., Takigawa, S., Noda, T., Matsuura-Endo, C. and Yamauchi, H. 2008. Comparison of phenolic compositions between common and tartary buckwheat (Fagopyrum) sprouts. Food Chem. 110, 814-820. DOI |
5 | Kwon, T. B. 1994. Change in rutin and fatty acids buckwheat during germination. Kor. J. Food Nutr. 7, 124-127. |
6 | Kraujalis, P., Venskutonis, P. R., Ibanez, E. and Herrero, M. 2015. Optimization of rutin isolation from Amaranthus paniculatus leaves by high pressure extraction and fractionation techniques. J. Supercrit. Fluids 104, 234-242. DOI |
7 | Kreft, I., Fabjan, N. and Yasumoto, K. 2006. Rutin content in buckwheat (Fagopyrum esculentum Moench) food materials and products. Food Chem. 98, 508-512. DOI |
8 | Liu, C. L., Chen, Y. S., Yang, J. H. and Chiang, B. H. 2008. Antioxidant activity of tartary (Fagopyrum tataricum (L.) Gaertn.) and common (Fagopyrum esculentum Moench) buckwheat sprouts. J. Agric. Food Chem. 56, 173-178. DOI |
9 | Mukhtar, H., Das, M., Khan, W. A., Wang, Z. Y., Bik, D. P. and Bickers, D. R. 1988. Exceptional activity of tannic acid among naturally occurring plant phenols in protecting against 7,12-dimethylbenz(a)anthracene-, benzo(a)-pyrene-, 3-methylcholanthrene-, and N-methyl-N-nitrosourea-induced skin tumorigenesis in mice. Cancer Res. 48, 2361-2365. |
10 | Ong, K. C. and Khoo, H. E. 1997. Biological effects of myricetin. Gen. Pharmacol.: The Vascular System. 29, 121-126. DOI |
11 | Przybylski, R., Lee, Y. C. and Eskin, N. A. M. 1998. Antioxidant and radical scavenging activities of buckwheat seed components. J. Am. Oil Chem. Soc. 75, 1595. DOI |
12 | Fabjan, N., Rode, J., Kosir, I. J., Wang, Z., Zhang, Z. and Kreft, I. 2003. Tartary Buckwheat (Fagopyrum tatarium Gaertn.) as a source of dietary rutin and quercetin. J. Argric. Food Chem. 51, 6452-6455. DOI |
13 | Utesch, D., Feige, K., Dasenbrock, J., Broschard, T. H., Harwood, M., Danielewska-Nikiel, B. and Lines, T. C. 2008. Evaluation of the potential in vivo genotoxicity of quercetin. Mutat. Res. 654, 38-44. DOI |
14 | Zhang, Z. L., Zhou, M. L., Tang, Y., Li, F. L., Tang, Y. X., Shao, J. R., Xue, W. T. and Wu, Y. M. 2012. Bioactive compounds in functional buckwheat food. Food Res. Int. 49, 389-395. DOI |
15 | Aguirre, L., Arias, N., Macarulla, M. T., Gracia, A. and Portillo, M. P. 2011. Beneficial effects of quercetin on obesity and diabetes. Open Nutraceuticals J. 4, 189-198. DOI |
16 | Boots, A. W., Li, H., Schins, R. P., Duffin, R., Heemskerk, J. W., Bast, A. and Haenen, G. R. 2007. The quercetin paradox. Toxicol. Appl. Pharmacol. 222, 89-96. DOI |
17 | Carocho, M. and Ferreira, I. C. 2013. A review on antioxidants, prooxidants and related controversy: natural and synthetic compounds, screening and analysis methodologies and future perspectives. Food Chem. Toxicol. 51, 15-25. DOI |
18 | Davis, J. M., Murphy, E. A. and Carmichael, M. D. 2009. Effects of the dietary flavonoid quercetin upon performance and health. Curr. Sports Med. Rep. 8, 206-213. DOI |
19 | Davis, J. M., Zhao, Z., Stock, H. S., Mehl, K. A., Buggy, J. and Hand, G. A. 2003. Central nervous system effects of caffeine and adenosine on fatigue. Am. J. Physiol. Regul. Integr. Comp. Physiol. 208, 399-404. |
20 | Harwood, M., Danielewska-Nikiel, B., Borzelleca, J. F., Flamm, G. W., Williams, G. M. and Lines, T. C. 2007. A critical review of the data related to the safety of quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic/carcinogenic properties. Food Chem. Toxicol. 45, 2179-2205. DOI |
21 | Heo, H. J., Lee, H. N., Kim, Y. H., Jeong, H. S. and Lee, J. S. 2019. Optimization of ultrasound-assisted extraction of antioxidant compounds from onion peels using response surface methodology. J. Kor. Soc. Food Sci. Nutr. 48, 441-446. DOI |
22 | Jang, M., Asnin, L., Nile, S. H., Keum, Y. S., Kim, H. Y. and Park, S. W. 2013. Ultrasound assisted extraction of quercetin from onion solid wastes. Int. J. Food Sci. Technol. 48, 246-252. DOI |
23 | Kang, N. J. 2015. Rutin suppresses neoplastic cell transformation by inhibiting ERK and JNK signaling pathways. J. Kor. Soc. Food Sci. Nutr. 28, 579-585. |
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