Anti-inflammatory Activity of Antimicrobial Peptide Protaetiamycine 2 Derived from the Protaetia brevitarsis seulensis
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Lee, Joon Ha
(Department of Agricultural Biology, National Institute of Agricultural Sciences, Rural Development Administration)
Baek, Minhee (Department of Agricultural Biology, National Institute of Agricultural Sciences, Rural Development Administration) Lee, Hwa Jeong (Department of Agricultural Biology, National Institute of Agricultural Sciences, Rural Development Administration) Kim, In-Woo (Department of Agricultural Biology, National Institute of Agricultural Sciences, Rural Development Administration) Kim, Sun Young (Department of Agricultural Biology, National Institute of Agricultural Sciences, Rural Development Administration) Seo, Minchul (Department of Agricultural Biology, National Institute of Agricultural Sciences, Rural Development Administration) Kim, Mi-Ae (Department of Agricultural Biology, National Institute of Agricultural Sciences, Rural Development Administration) Kim, Seong Hyun (Department of Agricultural Biology, National Institute of Agricultural Sciences, Rural Development Administration) Hwang, Jae Sam (Department of Agricultural Biology, National Institute of Agricultural Sciences, Rural Development Administration) |
1 | Bhor, V. M., Thomas, C. J., Surolia, N. and Surolia, A. 2005. Polymyxin B: an ode to an old antidote for endotoxic shock. Mol. Biosyst. 1, 213-222. DOI |
2 | Brandenburg, K., Andra, J., Garidel, P. and Gutsmann, T. 2011. Peptide-based treatment of sepsis. Appl. Microbiol. Biotechnol. 90, 799-808. DOI |
3 | Chung, M. Y., Hwang, J. S., Goo, T. W. and Yun, E. Y. 2013. Analysis of general composition and harmful material of Protaetia brevitarsis. J. Life Sci. 23, 664-668. DOI |
4 | Gasparini, C. and Feldmann, M. 2012. NF-kB as a target for modulating inflammatory responses. Curr. Pharm. Des. 18, 5735-5745. DOI |
5 | Hwang, J. S., Kang, B. R., Kim, S. R., Yun, E. Y., Park, K. H., Jeon, J. P., Suh, H. J., Nam, S. H. and Kim, I. 2008. Molecular characterization of a defensin-like peptide from larvae of a beetle, Protaetia brevitarsis. Int. J. Indust. Entomol. 17, 131-135. |
6 | Lehrer, R. I., Rosenman, M., Harwig, S. S., Jackson, R. and Eisenhauer, P. 1991. Designer assays for antimicrobial peptides. J. Immunol. Methods 137, 167-173. DOI |
7 | Lowenstein, C. J., Dinerman, J. L. and Snyder, S. H. 1994. Nitric oxide: a physiologic messenger. Ann. Intern. Med. 120, 227-237. DOI |
8 | Lu, Y. C., Yeh, W. C. and Ohashi, P. S. 2008. LPS/TLR4 signal transduction pathway. Cytokine 42, 145-151. DOI |
9 | Malmsten, M. 2016. Interactions of antimicrobial peptides with bacterial membranes and menbrane components. Curr. Top. Med. Chem. 16, 16-24. DOI |
10 | Martin, G. S., Mannino, D. M., Eaton, S. and Moss, M. 2003. The epidemiology of sepsis in the United States from 1979 through 2000. N. Engl. J. Med. 348, 1546-1554. DOI |
11 |
Qin, H., Wilson, C. A., Lee, S. J., Zhao, X. and Benveniste, E. N. 2005. LPS induces CD40 gene expression through the activation of NF-kappaB and STAT- |
12 | Ronco, C. 2014. Lipopolysaccharide (LPS) from the cellular wall of Gram-negative bacteria, also known as endotoxin, is a key molecule in the pathogenesis of sepsis and septic shock. Preface. Blood Purif. 37 Suppl 1, 1. DOI |
13 | Lee, J., Bang, K., Hwang, S. and Cho, S. 2016. cDNA cloning and molecular characterization of a defensin-like antimicrobial peptide from larvae of Protaetia brevitarsis seulensis (Kolbe). Mol. Biol. Rep. 43, 371-379. DOI |
14 | Hwang, J. S., Lee, J., Kim, Y. J., Bang, H. S., Yun, E. Y., Kim, S. R., Suh, H. J., Kang, B. R, Nam, S. H., Jeon, J. P., Kim, I. and Lee, D. G. 2009. Isolation and characterization of a defensin-like Peptide (coprisin) from the dung beetle, Copris tripartitus. Int. J. Pept. 2009, 2009. |
15 | Karima, R., Matsumoto, S., Higashi, H. and Matsushima, K. 1999. The molecular pathogenesis of endotoxic shock and organ failure. Mol. Med. Today 5, 123-132. DOI |
16 | Kumar, P., Kizhakkedathu, J. N. and Straus, S. K. 2018. Antimicrobial peptides: diversity, mechanism of action and strategies to improve the activity and biocompatibility in vivo. Biomolecules 8, 4. DOI |
17 | Rosenfeld, Y. and Shai, Y. 2006. Lipopolysaccharide (Endotoxin)-host defense antibacterial peptides interactions: role in bacterial resistance and prevention of sepsis. Biochim. Biophys. Acta. 1758, 1513-1522. DOI |
18 | Shin, S., Kim, J. K., Lee, J. Y., Jung, K. W., Hwang, J. S., Lee, J., Lee, D. G, Kim, I., Shin, S. Y. and Kim, Y. 2009. Design of potent 9-mer antimicrobial peptide analogs of protaetiamycine and investigation of mechanism of antimicrobial action. J. Pept. Sci. 15, 559-568. DOI |
19 | Kwon, E. Y., Yoo, J., Yoon, Y. I., Hwang, J. S., Goo, T. W., Kim, M. A., Choi, Y. C. and Yun, E. Y. 2013. Pre-treatment of the white-spotted flower chafer (Protaetia brevitarsis) as an ingredient for novel foods. J. Kor. Soc. Food Sci. Nutr. 42, 397-402. DOI |
20 | Lee, E., Kim, J. K., Shin, S., Jeong, K. W., Lee, J., Lee, D. G., Hwang, J. S. and Kim, Y. 2011. Enantiomeric 9-mer peptide analogs of protaetiamycine with bacterial cell selectivities and anti-inflammatory activities. J. Pept. Sci. 17, 675-682. DOI |
21 | Lee. J., Hong, H. J., Kim, J. K., Hwang, J. S., Kim, Y. and Lee, D. G. 2009. A novel antifungal analog peptide derived from protaetiamycine. Mol. Cells 28, 473-477. DOI |
22 | Lee, J. and Lee, D. G. 2015. Antimicrobial peptides (AMPs) with dual mechanisms: membrane disruption and Apoptosis. J. Microbiol. Biotechnol. 25, 759-764. DOI |
23 | Lee, S. Y., Moon, H. J., Kurata, S., Kurama, T., Natori, S. and Lee, B. L. 1994. Purification and molecular cloning of cDNA for an inducible antibacterial protein of larvae of a coleopteran insect, Holotrichia diomphalia. J. Biochem. 115, 82-86. DOI |
24 | Yoon, H. S., Lee, C. S., Lee, S. Y., Choi, C. S., Lee, I. H., Yeo, S. M. and Kim, H. R. 2003. Purification and cDNA cloning of inducible antibacterial peptides from Protaetia brevitarsis (Coleoptera). Arch. Insect Biochem. Physiol. 52, 92-103. DOI |
25 | Zhang, L. J. and Gallo, R. L. 2016. Antimicrobial peptides. Curr. Biol. 26, R14-R19. DOI |
26 | Lee, J., Lee, W., Kim, M. A., Hwang, J. S., Na, M. and Bae, J. S. 2017. Inhibition of platelet aggregation and thrombosis by indole alkaloids isolated from the edible insect Protaetia brevitarsis seulensis (Kolbe). J. Cell. Mol. Med. 21, 1217-1227. DOI |
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