Inhibitory Effect of the Ethanol Extract of Rudbeckia laciniata var. hortensis Bailey on Adipocyte Differentiation in 3T3-L1 Cells
![]() |
Nam, Gun He
(Department of Biological Science and Biotechnology, Hannam University)
Wee, Ji-Hyang (Department of Food Science & Bio Technology, Shinansan University) Kim, Sang Yung (Department of Food Science & Bio Technology, Shinansan University) Baek, Ji-Young (Department of Pharma-Gene Co., Ltd.) Kim, Young Min (Department of Biological Science and Biotechnology, Hannam University) |
1 | Ali, A. T., Hochfeld, W. E., Myburgh, R. and Pepper, M. S. 2013. Adipocyte and adipogenesis. Eur. J. Cell. Biol. 92, 229-236. DOI |
2 | Chu, C. S., Rhim, T. J., Kim, D. H. and Kwon, K. R. 2008. The effects of hot pepper extract and capsaicin on adipocyte metabolism. J. Pharmacopuncture 11, 149-162. DOI |
3 | Flier, J. S. and Maratos-Flier, E. 1998. Obesity and the hypothalamus: novel peptides for new pathways. Cell 92, 437-440. DOI |
4 | Friedman, J. M. 2000. Obesity in the new millennium. Nature 404, 632. DOI |
5 | Gesta, S., Tseng, Y. H. and Kahn, C. R. 2007. Developmental origin of fat: tracking obesity to its source. Cell 131, 242-256. DOI |
6 | Goodwin, P. J. and Stambolic, V. 2015. Impact of the obesity epidemic on cancer. Annu. Rev. Med. 66, 281-296. DOI |
7 | Gregoire F. M., Smas C. M. and Sul H. S. Under standing adipocyte differentiation. Physiol. Rev. 78, 783-809. DOI |
8 | Green, H. and Kehinde, O. 1976. Spontaneous heritable changes leading to increased adipose conversion in 3T3 cells. Cell 7, 105-113. DOI |
9 | Grulke, N. E., Neufeld, H. S., Davison, A. W., Roberts, M. and Chappelka, A. H. 2007. Stomatal behavior of ozonesensitive and‐insensitive coneflowers (Rudbeckia laciniata var. digitata) in Great Smoky Mountains National Park. New. Phytol. 173, 100-109. DOI |
10 | Green, L. M., Reade, J. L. and Ware, C. F. 1984. Rapid colormetric assay for cell viability: application to the quantitation of cytotoxic and growth inhibitory lymphokines. J. Immunol. Methods 70, 257-268. DOI |
11 | Ko, J. H., Kwon, H. S., Yoon, J. M., Yoo, J. S., Jang, H. S., Kim, J. Y. and Kang, J. H. 2015. Effects of Polygonatum sibiricum rhizome ethanol extract in high-fat diet-fed mice. Pharm. Biol. 53, 563-570. DOI |
12 | Jang, M. J., Yang, J. H. and Kim, E. J. 2018. Protein Arginine Methyltransferase 5 (PRMT5) Regulates Adipogenesis of 3T3L-1 Cells. J. Life Sci. 28, 765-771. DOI |
13 | Kim, J., Park, J. and Jun, W. 2014. Anti-obesity effect of ethyl acetate fraction from 50% ethanol extract of fermented Curcuma longa L. in 3T3-L1 cells. Prev. Nutr. Food. Sci. 43, 1681-1687. |
14 | Kim, J. B. and Park, J. Y. 2002. Molecular insights into fat cell differentiation and functional roles of adipocytokines. Endocrinol. Metab. 17, 1-9. |
15 | Kwon, D. H., Choi, Y. H., Kim, B. W. and Hwang, H. J. 2019. Effects of Ethanol Extract of Sargassum horneri on Adipocyte Differentiation and Adipogenesis in 3T3-L1 Preadipocytes. J. Life Sci. 29, 209-214. DOI |
16 | Liu, F., Kim, J. K., Li, Y., Liu, X. Q., Li, J. and Chen, X. 2001. An extract of Lagerstroemia speciosa L. has insulin-like glucose uptake-stimulatory and adipocyte differentiation-inhibitory activities in 3T3-L1 cells. J. Clin. Nutr. Food. Sci. 131, 2242-2247. |
17 |
Livak, K. J. and Schmittgen, T. D. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2- |
18 | Rosen, E. D. and MacDougald, O. A. 2006. Adipocyte differentiation from the inside out. Nat. Rev. Mol. Cell. Biol. 7, 885. DOI |
19 | Park, S. J., Lee, I. S., Lee, S. P. and Yu, M. H. 2013. Inhibition of adipocyte differentiation and adipogenesis by supercritical fluid extracts and marc from Cinnamomum verum. J. Life Sci. 23, 510-517. DOI |
20 |
Rosen, E. D., Hsu, C. H., Wang, X., Sakai, S., Freeman, M. W., Gonzalez, F. J. and Spiegelman, B. M. 2002. |
21 | Song, M. Y., Bose, S. and Kim, H. J. 2013. Effect of probiotics- fermented Samjunghwan on differentiation in 3T3- L1 preadipocytes. Prev. Nutr. Food. Sci. 42, 1-7. |
22 | Wang, N. D., Finegold, M. J., Bradley, A., Ou, C. N., Abdelsayed, S. V., Wilde, M. D. and Darlington, G. J. 1995. Impaired energy homeostasis in C/EBP alpha knockout mice. Science 269, 1108-1112. DOI |
![]() |