Dependency on p53 in Expression Changes of ATF3 and NAG-1 Induced by EGCG, Genistein, and Resveratrol
![]() |
Kim, Min-Jeong
(Department of Biological Sciences, Andong National University)
Kim, Hyun-Ji (Department of Biological Sciences, Andong National University) Seo, Yu-Mi (Department of Biological Sciences, Andong National University) Lee, Eun-Joo (Department of Biological Sciences, Andong National University) Kim, Jong-Sik (Department of Biological Sciences, Andong National University) |
1 | Hackl, C., Lang, S. A., Moser, C., Mori, A., Fichtner-Feigl, S., Hellerbrand, C., Dietmeier, W., Schlitt, H. J., Geissler, E. K. and Stoeltzing, O. 2010. Activating transcription factor-3 (ATF3) functions as a tumor suppressor in colon cancer and is up-regulated upon heat-shock protein 90 (Hsp90) inhibition. BMC Cancer 10, 668. DOI |
2 | Huang, C. Y., Han, Z., Li, X., Xie, H. H. and Zhu, S. S. 2017. Mechanism of EGCG promoting apoptosis of MCF-7 cell line in human breast cancer. Oncol. Lett. 14, 3623-3627. DOI |
3 | Kang, S. U., Lee, B. S., Lee, S. H., Baek, S. J., Shin, Y. S. and Kim, C. H. 2013. Expression of NSAID-activated gene-1 by EGCG in head and neck cancer: involvement of ATM-dependent p53 expression. J. Nutr. Biochem. 24, 986-999. DOI |
4 | Khan, N. and Mukhtar, H. 2013. Tea and health: studies in humans. Curr. Pharm. Des. 19, 6141-6147. DOI |
5 | Lane, D. and Levine, A. 2010. p53 Research: the past thirty years and the next thirty years. Cold Spring Harb. Perspect. Biol. 2, a000893. |
6 | Mohanty, S, Adhikary, A., Chakrabarty, S., Sa, G. and Das, T. 2012. Operation 'p53 Hunt' to combat cancer: theaflavins in action. Front Biosci. (Schol Ed) 4, 300-320. |
7 | Levav-Cohen, Y., Goldberg, Z., Tan, K. H., Alsheich-Bartok, O., Zuckerman, V., Haupt, S. and Haupt, Y. 2014. The p53-Mdm2 loop: a critical juncture of stress response. Subcell. Biochem. 85, 161-186. |
8 | Liu, L., Ju, Y., Wang, J. and Zhou, R. 2017. Epigallocatechin -3-gallate promotes apoptosis and reversal of multidrug resistance in esophageal cancer cells. Pathol. Res. Pract. 213, 1242-1250. DOI |
9 | Maru, G. B., Hudlikar, R. R., Kumar, G., Gandhi, K. and Mahimkar, M. B. 2016. Understanding the molecular mechanisms of cancer prevention by dietary phytochemicals: From experimental models to clinical trials. World J. Biol. Chem. 7, 88-99. DOI |
10 | Baek, S. J., Wilson, L. C. and Eling, T. E. 2002. Resveratrol enhances the expression of non-steroidal anti-inflammatory drug-activated gene (NAG-1) by increasing the expression of p53. Carcinogenesis 23, 425-434. DOI |
11 | Bottone, F. G. Jr. and Alston-Mills, B. 2011. The dietary compounds resveratrol and genistein induce activating transcription factor 3 while suppressing inhibitor of DNA binding/ differentiation-1. J. Med. Food. 14, 584-593. DOI |
12 | Moradzadeh, M., Hosseini, A., Erfanian, S. and Rezaei, H. 2017. Epigallocatechin-3-gallate promotes apoptosis in human breast cancer T47D cells through down-regulation of PI3K/AKT and Telomerase. Pharmacol. Rep. 69, 924-928. DOI |
13 | Cho, K. N., Sukhthankar, M., Lee, S. H., Yoon, J. H. and Baek, S. J. 2007. Green tea catechin (-)-epicatechin gallate induces tumour suppressor protein ATF3 via EGR-1 activation. Eur. J. Cancer 43, 2404-2412. DOI |
14 | Du, G. J., Zhang, Z., Wen, X. D., Yu, C., Calway, T., Yuan, C. S. and Wang, C. Z. 2012. Epigallocatechin Gallate (EGCG) is the most effective cancer chemopreventive polyphenol in green tea. Nutrients 4, 1679-1691. DOI |
15 | Zhang, Z., Wang, C. Z., Du, G. J., Qi, L. W., Calway, T., He, T. C., Du, W. and Yuan, C. S. 2013. Genistein induces G2/M cell cycle arrest and apoptosis via ATM/p53-dependent pathway in human colon cancer cells. Int. J. Oncol. 43, 289-296. DOI |
16 | Moseley, V. R., Morris, J., Knackstedt, R. W. and Wargovich, M. J. 2013. Green tea polyphenol epigallocatechin 3-gallate, contributes to the degradation of DNMT3A and HDAC3 in HCT116 human colon cancer cells. Anticancer Res. 33, 5325-5333. |
17 | Parrales, A. and Iwakuma, T. 2015. Targeting oncogenic mutant p53 for cancer therapy. Front. Oncol. 5, 288. |
18 |
Shin, Y. S., Kang, S. U., Park, J. K., Kim, Y. E., Kim, Y. S., Baek, S. J., Lee, S. H. and Kim, C. H. 2016. Anti-cancer effect of (-)-epigallocatechin-3-gallate (EGCG) in head and neck cancer through repression of transactivation and enhanced degradation of |
19 | Tan, A. C., Konczak, I., Sze, D. M. and Ramzan, I. 2011. Molecular pathways for cancer chemoprevention by dietary phytochemicals. Nutr. Cancer 63, 495-505. DOI |
20 | Vanamala, J., Reddivari, L., Radhakrishnan, S. and Tarver, C. 2010. Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/Wnt and activation of p53 signaling pathways. BMC Cancer 10, 238. DOI |
21 | Vaseva, A. V. and Moll, U. M. 2009. The mitochondrial p53 pathway. Biochim. Biophys. Acta. 1787, 414-420. DOI |
22 | Wilson, L. C., Baek, S. J., Call, A. and Eling, T. E. 2003. Nonsteroidal anti-inflammatory drug-activated gene (NAG-1) is induced by genistein through the expression of p53 in colorectal cancer cells. Int. J. Cancer 105, 747-753. DOI |
23 | Xie, J. J., Xie, Y. M., Chen, B., Pan, F., Guo, J. C., Zhao, Q., Shen, J. H., Wu, Z. Y., Wu, J. Y., Xu, L. Y. and Li, E. M. 2014. ATF3 functions as a novel tumor suppressor with prognostic significance in esophageal squamous cell carcinoma. Oncotarget 5, 8569-8582. |
![]() |