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http://dx.doi.org/10.5352/JLS.2018.28.3.320

Physiological Activity of Five Kinds of Medicinal Plant Extracts with Various Solvents and Their Composites  

Shin, Ji Hyeon (Namhae Garlic Research Institute)
Kang, Jea Ran (Namhae Garlic Research Institute)
Kang, Min Jung (Namhae Garlic Research Institute)
Shin, Jung Hye (Namhae Garlic Research Institute)
Publication Information
Journal of Life Science / v.28, no.3, 2018 , pp. 320-330 More about this Journal
Abstract
This study was performed to investigate the antioxidative activity of solvent (water, 50% ethanol, and 100% ethanol) extracts from five kinds of medicinal herbs Cutellaria baicalensis Georgi; SB, Paeonia lactiflora Pall.; PA, Salvia miltiorrhiza Bunge; SM, Phellinus linteus; PH, Morus alba L.; MA). The total content of phenolic compounds was highest in the 50% ethanol extract from PH (280.05 mg/g), the 100% ethanol extract from PH (308.88 mg/g), and the water extract from SM (80.27 mg/g). The total content of flavonoids was highest in the 50% ethanol extract from SB (62.71 mg/ml), the 100% ethanol extract from SB (64.59 mg/ml), and the water extract from SM (35.85 mg/ml). ACE inhibitory activity only occurred in the water extracts, and it was highest in the water extract from SB (45.33%). Cholesterol adsorption activity was higher in the SB and PA extracts than in the other extracts. In water extracts, SM showed the highest antioxidative activity. Among the 50% and 100% ethanol extracts, DPPH radical scavenging activity and FRAP were highest in the PH extract, and ABTS radical scavenging activity was significantly higher in the PA extracts. Seven types of compositions were prepared with different mixing ratios of 0.2 to 2.0 from relatively high-activity medicinal herbs, such as PH, SM and PA. The total phenolic and flavonoid compound contents of the compositions were 50.53-61.96 and 16.91-33.81 mg/ml, respectively. Cholesterol adsorption activity was 46.27-70.03%.
Keywords
ACE inhibitory activity; antioxidant; cholesterol adsorption capacity; medicinal herbs;
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