Browse > Article
http://dx.doi.org/10.5352/JLS.2016.26.8.911

Prevalence of Noroviruses Detected from Outbreaks of Acute Gastroenteritis in Busan, Korea  

Koo, Hee Soo (Busan Metropolitan Government Research Institute of Public Health & Environment)
Ku, Pyeong Tae (Busan Metropolitan Government Research Institute of Public Health & Environment)
Lee, Mi Ok (Busan Metropolitan Government Research Institute of Public Health & Environment)
Baik, Hyung Suk (Department of Microbiology, Pusan National University)
Publication Information
Journal of Life Science / v.26, no.8, 2016 , pp. 911-920 More about this Journal
Abstract
Norovirus is the most common causative agent of acute gastroenteritis. This study was carried out to investigate molecular epidemiology of norovirus infections from outbreaks in Busan from 2012 to 2015. Total of 581 stool specimens were collected from diarrhea patients in outbreaks in Busan, 71 samples were resulted in positive to norovirus. The data were analyzed according to seasonality, patient, age and gender. Noroviruses were detected most frequently during the winter season from November (25.4%) to February (28.2%). The age group from teens was the most susceptible to norovirus infections. To obtain the molecular genetic information of norovirus, we performed sequencing analyses of the strains detected. Norovirus genotypes have been reported to show high genetic diversity. Four kinds of GI genotypes (GI-1, GI-2, GI-3, GI-5) and five kinds of GII genotypes (GII-1, GII-4, GII-5, GII-6, GII-17) were indentified in outbreaks in Busan. Other previous studies have shown that GII-4 is the most predominant circulating in Korea and worldwide. The most prevalent norovirus genotypes of each year were GII-6 in 2012, GII-6 in 2013, GII-4 in 2014 and GII-6 in 2015. Except for 2014, GII-6 genotype was the most prevalent and predominant in Busan. We described the epidemiological analysis of the noroviruses in outbreaks in Busan. The result of this study will contribute to update the epidemiological data and improve hygiene and public health via sustainable surveillance.
Keywords
Gastroenteritis; genotype; norovirus; outbreaks;
Citations & Related Records
Times Cited By KSCI : 3  (Citation Analysis)
연도 인용수 순위
1 Kazuhiro, O., Tomoichiro, O., Naokazu, T. and Grant, S. H. 2007. Norovirus infections in symptomatic and asymptomatic food-handlers in Japan. J. Clin. Microbiol. 45, 3996-4005.   DOI
2 Kim, N. H., Min, S. K., Park, E. H. and Park, Y. 2010. Study on gastroenteric norovirus genotypes in busan, Korea 2008 to 2010. Rep. Busan Inst. 20, 9-17.
3 Kroneman, A., Vega, E., Vennema, H., Vinje, J., White, P. A., Hansman, G., Green, K., Martella, V., Katayama, K. and Koopmans, M. 2013. Proposal for a unified norovirus nomenclature and genotyping. Arch. Virol. 158, 2059-2068.   DOI
4 Kroneman, A., Vennema, H., Deforche, K., v d Avoort, H., Peñaranda, S., Oberste, M. S., Vinjé, J. and Koopmans, M. 2011. An automated genotyping tool for enteroviruses and norovirueses. J. Clin. Virol. 51, 121-125.   DOI
5 Lee, M. H., Seo, D. T., Seo, J., Wang, X., Lee, J. S., Joo, I. S., Lee, S. H., Park, G. S., Ha, S. D. and Choi, C. 2013. Trends and epidemiology of norovirus outbreaks. J. Fd Hyg. Safety. 8, 3-11.
6 Lopman, B. A., Reacher, M. H., Vipond, I. B., Sarangi, J. and Brown, D. W. 2003. Clinical manifestation of norovirus gastroenteritis health care setting. Clin. Infect. Dis. 39, 318-324.
7 Lopman, B., Vennma, H., Kohli, E., Potjier, P., Sanchez, A., Negrodo, A., Buesa, J., Schreier, E., Reacher, M., Brown, D., Gray, J., Iturriza, M., Gallimore, C., Bottiger, B., Hedlund, K. O., Torven, M., von Bonsdorff, C. H., Maunula, L., Poljsk-Prijatelj, M., Zimsek, J., Reuter, G., Szux, G., Melegh, B., Svennson, L., van Duijnhoven, Y. and Koopmans, M. 2004. Increase in viral gastroenteritis outbreaks in Europe and epidemic spread of new norovirus variant. Lancet 363, 682-688.   DOI
8 Mayo, M. A. 2002. A summary of taxonomic changes recently approved by ICTV. Arch. Virol. 147, 655-663.
9 Oh, S. A., Park, S. H., Ham, H. J., Seung, H. J., Jang, J. I., Duh, S. W., Jo, S. J., Choi, S. M. and Jeong, H. S. 2013. Molecular charcterization of norovirus and rotavirus in outbreak of acute gastroenteritics in Seoul. J. Bacteriol. Virol. 43, 307-316.   DOI
10 Okame, M., Akihara, S., Hansman, G., Hainian, Y., Tran, H. T., Phan, T. G., Yagyu, F., Okitus, S. and Ushijima, H. 2006. Existence of multiple genotypes associated with acute gastroenteritis during 6-year survey of norovirus infection in Japan. J. Med. Virol. 78,1318-1324.   DOI
11 Parashar, U., Quiroz, E. S., Mounts, A. W., Monroe, S. S., Fankhauser, R. L., Ando, T., Noel, T., Noel, J. S., Bulens, S. N., Beard, S. R., Li, J. F., Bresee, J. S. and Glass, R. I. 2001. Norwalk-like virus, Public health consequences and outbreak management, MMWR Recomm Rep. 50, 1-17.
12 Park, K. S., Jeong, H. S., Baek, K. A., Lee, C. G., Park, S. M., Park, J. S., Choi, H. U. and Cheon, D. S. 2010. Genetic analysis of norovirus GII.4 variants circulating in Korea in 2008. Arch. Virol. 155, 635-641.   DOI
13 Patel, M. M., Hall, A. J., Vinje, J. and Parashar, U. D. 2009. Noroviruses a comprehensive review. J. Clin. Virol. 44, 1-8.   DOI
14 Svraka, S., Duizer, E., Vennema, H., de Bruin, E., van der Veer, B., Dorresteijn, B. and Koopmans, M. 2007. Etiological role of viruses in outbreaks of acute gastroenteritis in the Netherlands from 1994 through 2005. J. Clin. Microbiol. 45, 1389-1394.   DOI
15 Tamaki, O., Shin-ichi, Y., Yasuo, O., Hironori, O., Yasuhiro, Y., Masayuko, K., Koichi, Y. and Nobuhiro, F. 2008. Occurrence of norovirus infections unrelated to norovirus outbreaks in an asymptomatic food handler population. J. Clin. Microbiol. 46, 1985-1988.   DOI
16 Zheng, D. P., Widdowson, M. A., Glass, R. I. and Vinje, J. 2010. Molecular epidemiology of genogroup II-genotype 4 noroviruses in the United States between 1994 and 2006. J. Clin. Microbiol. 48, 168-177.   DOI
17 Tokyo welfare health center, norovirus corresponding standard manual for social welfare providers, Social welfare council of social welfare in Tokyo, Japan.
18 Tuan Zaianzar, C., Hidayah, M. S., Chai, L. C., Tunung, R., Ghazali, F. M. and Son, R. 2010. The scenario of norovirus contamination in food and food handlers. J. Microbiol. Biotechnol. 20, 229-237.
19 Van Beek, J., Ambert-Balay, K., Bottledoom, N., Eden, J. S., Fonager, J., Hewitt, J., Iritani, N., Kroneman, A., Vennema, H., Vinjé, J., White, P. A. and Koopmans, M. 2013. Indication for worldwide increased norovirus activity associated with emergence of a new varient of genotype GII.4 late 2013. Euro. Surveill. 18, 8-9.
20 Adler, J. L. and Zickl, R. 1969. Winter vomiting disease. J. Infect. Dis. 119, 668-673.   DOI
21 Anderson, A. D., Heryford, A. G., Sarisky, J. P., Higgins, C., Monroe, S. S., Beard, S., Newport, C. M., Cashdollar, J. L., Fout, G. S., Robbins, D. E., Seys, S. A., Musgrave, K. J., Medus, C., Vinj, J., Bresee, J. S., Mainzer, H. M. and Glass, R.I. 2003. A waterborne outbreak of Norwalk-like virus among snowmibilers-Wyoming, 2001. J. Infect. Dis. 187, 303-306.   DOI
22 Ando, T., Mulders, M. N., Lewis, D. C., Estes, M. K., Monroe, S. S. and Glass, R. I. 2003. A waterborne outbreak of Norwalk-like virus among snowmobilers-Wyoming, 2001. J. Infect. Dis. 187, 303-306.   DOI
23 Cater, M. J. 2005. Enterically infecting viruses: pathogenicity, transmission and significance for food and waterborne infection. J. Appl. Microbiol. 98, 1354-1380.   DOI
24 Beller, M., Ellis, A., Lee, S. H., Drebot, M. A., Jenkerson, S. A., Funk, E., Sobsey, M. D., Simmons, O. D., Monroe, S. S., Ando, T., Noel, F., Petric, M., Middaugh, J. P. and Spika, J. S. 1997. Outbreak of viral gastroenteritis due to a contaminated well. International consequences. JAMA. 278, 563-568.   DOI
25 Belliot, G., Noel, J. S., Li, J. F., Seto, Y., Humphrey, C. D., Ando, T., Class, R. I. and Monroe, S. S. 2001. Characterization of capsid genes, expressed in the baculovirus system, of three new genetically distinct strains of Norwalk-like viruses. J. Clin. Microbiol. 39, 4288-4295.   DOI
26 Boccia, D., Tozzi, A. E., Cotter, B., Cotter, C., Russo, T., Buttinelli, G., Caprioli, A., Marziano, M. L. and Ruggeri, F. M. 2002. Water-borne outbreak of Norwalk-like virus gastroenteritis at a tourist resort Italy. Emerg. Infect. Dis. 8, 563-568.   DOI
27 Chikhi-Brachet, R., Bon, F., Toubiana, L., Pothier, P., Nicolas, J. C., Flahault, A. and Kohli, E. 2002. Virus diversity in a winter epidemic if acute diarrhea in France. J. Clin. Microbiol. 40, 4266-4272.   DOI
28 Dey, S. K., Nguyen, T., ANishio, O., Salim, A. F., Rahman, M., Yagyu, F., Okitsu, S. and Ushijima, H. 2007. Molecular and epidemiological trend of norovirus associated gastroenteritis in Dhaka city, Bangladesh. J. Clin. Virol. 40, 218-223.   DOI
29 Green, J., Wright, P. A., Gallimore, C. I., Mitchell, O., Morgan Capner, P. and Brown, D. W. 1998. The role of environmental contamination with small round structured viruses in a hospital outbreak investigated by reverse-transcriptase polymerase chain reaction assay. J. Hosp. Infect. 39, 39-45.   DOI
30 Green, K. Y. 2007. Caliciviridae : The noroviruse, In Fields Virology. pp. 949-979, 5th ed., Lippincott Williams & Wilkins, Philadelphia, USA.
31 Green, K. Y., Ando, T., Balayan, M. S., Berke, T., Clarke, I. N., Estes, M. K., Matson, D. O., Nakata, S., Neill, J. D., Studert, M. J. and Thiel, H. J. 2000. Taxonomy of the caliciviruses, J. Infect. Dis. 18, 322-330.
32 Guntapong, R., Hansman, G. S., Oka, T., Ogawa, S., Kageyama, T., Pongsuwanna, Y. and Kateyama, K. 2004. Norovirus and sapovirus infections in Thailand. J. Infect. Dis. 57, 276-278.
33 Hall, A. J., Vinjé, J., Lopman, B., Park, G. W., Yen, C., Gregoricus, N. and Parashar, U. 2011. Updated norovirus outbreak management and disease prevention guidelines. MMWR Recomm. Rep. 60, 1-15.
34 Huh, J. W., Kim, W. H., Moon, S. G., Lee, J. B. and Lim, Y. H. 2009. Viral etiology and incidence associated with acute gastroenteritis in a 5-year survey in gyeonggi province, South korea. J. Clin. Virol. 44, 152-156.   DOI
35 Jeong, A. Y., Jeong, H. S., Lee, J. S., Park, Y. C., Lee, S. H., Hwang, I. G., Kim, Y. J., Kim, Y. J., Jung, S. Y. and Cheon, D.S. 2012. Occurrence of norovirus infections in asymptomatic food handlers in South korea. J. Clin. Microbiol. 51, 598-600.
36 Kapikian, A. Z., Wyatt, R. G., Dolin, R., Thornhill, T. S., Kalica, A. R. and Chanock, R. M. 1972. Visualization by immune electron microscopy of a 27-nm particle associated with acute infectious nonbacterial gastroenteritis. J. Virol. 10, 1075-1081.
37 Karst, S. M., Wobus, C. E., Lay, M., Davidson, J. and Virgin, H. W. 4th. 2003. STATI-dependent innate immunity to a Norwalk-like virus. Science 299, 1575-1578.   DOI