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http://dx.doi.org/10.5352/JLS.2016.26.11.1336

Five Genes Regulated by Oryctes rhinoceros nudivirus Infection in the Intestinal Tube of Allomyrina dichotoma  

Yoo, Bo-Kyung (Department of Biomedical Laboratory Science, College of Health & Welfare, Kyungwoon University)
Kwon, Kisang (Department of Anatomy and Cell Biology, College of Medicine, Chungnam National University)
Ko, Young Hwa (Department of Biomedical Laboratory Science, College of Health & Welfare, Kyungwoon University)
Lee, Eun Ryeong (Department of Anatomy and Cell Biology, College of Medicine, Chungnam National University)
Choi, Ji-Young (Applied Entomology Division, National Academy of Agricultural Science, RDA)
Kwon, O-Yu (Department of Biomedical Laboratory Science, College of Health & Welfare, Kyungwoon University)
Publication Information
Journal of Life Science / v.26, no.11, 2016 , pp. 1336-1340 More about this Journal
Abstract
Korean rhinoceros beetles (Allomyrina dichotoma), which can be found in broad-leaved forests in mountainous habitats and lives for around one year in wild. This beetle is currently popular as a pet and traditionally regarded as a medicine for liver-related diseases in Korea. It is reported that the economic losses in the mass-rearing facilities by virus infection have been increased since the 2010s in Korea. The causing virus for the A. dichotoma was firstly reported as an Oryctes rhinoceros nudivirus (OrNV) in 2015. We, here, observes that serious morphological changes in the intestinal tube from the OrNV-infected beetles, and report five genes, which are regulated by OrNV infection in the intestine; Krueppel-like factor 15 (Klf15), Endoplasmic reticulum aminopeptidase 2 (ERAP2), U5 small nuclear ribonucleoprotein 200 kDa helicase (Snrnp200), Muscleblind-like protein 2a (mbnl2a), and MIMI_L93. The results may provide a clue to the early diagnosis and disease treatment during the mass-rearing facilities of the A. dichotoma.
Keywords
Allomyrina dichotoma; infection; korean rhinoceros beetle; Oryctes rhinoceros nudivirus;
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1 Hattori, A. and Tsujimoto, M. 2013. Endoplasmic reticulum aminopeptidases: biochemistry, physiology and pathology. J. Biochem. 154, 219-228.   DOI
2 Ho, T. H., Charlet-B, N., Poulos, M. G., Singh, G., Swanson, M. S. and Cooper, T. A. 2004. Muscleblind proteins regulate alternative splicing. EMBO J. 23, 3103-3112.   DOI
3 Kim, Y., Han, Y. and Park, Y. 2016. The Plan for Activation of Insect Industry. Kor. Rural Econ. Inst. R758.
4 Lee, S., Park, K. H., Nam, S. H., Kwak, K. W. and Choi. J. Y. 2015. First report of Oryctes rhinoceros nudivirus (Coleoptera: Scarabaeidae) causing severe disease in Allomyrina dichotoma in Korea. J. Insect Sci. 15, DOI: 10.1093/jisesa/iev002.   DOI
5 Lux, S. E. 2016. Anatomy of the red cell membrane skeleton: unanswered questions. Blood 127, 187-199.   DOI
6 Manley, R., Boots, M. and Wilfert, L. 2015. Emerging viral disease risk to pollinating insects: ecological, evolutionary and anthropogenic factors. J. Appl. Ecol. 52, 331-340.   DOI
7 Paul, S., Dansithong, W., Kim, D., Rossi, J., Webster, N. J., Comai, L. and Reddy, S. 2006. Interaction of muscleblind, CUG-BP1 and hnRNP H proteins in DM1-associated aberrant IR splicing. EMBO J. 25, 4271-4283.   DOI
8 Sedgwick, S. G. and Smerdon, S. J. 1999. The ankyrin repeat: a diversity of interactions on a common structural framework. Trends Biochem. Sci. 24, 311-316.   DOI
9 Suh, H. J., Kim, S. R., Lee, K. S., Park, S. and Kang, S. C. 2010. Antioxidant activity of various solvent extracts from Allomyrina dichotoma (Arthropoda: Insecta) larvae. J. Photochem. Photobiol. B. 99, 67-73.   DOI
10 Than, T. T., Tran, G. V., Son, K., Park, E. M., Kim, S., Lim, Y. S. and Hwang, S. B. 2016. Ankyrin repeat domain 1 is up-regulated during hepatitis C virus infection and regulates hepatitis C virus entry. Sci. Rep. 6, 20819.   DOI
11 van Huis, A. 2013. Potential of insects as food and feed in assuring food security. Annu. Rev. Entomol. 58, 563-583.   DOI
12 Zhou, J., Tan, T., Tian, Y., Zheng, B., Ou, J. H., Huang, E. J. and Yen, T. S. 2011. Kruppel-like factor 15 activates hepatitis B virus gene expression and replication. Hepatology 54, 109-121.   DOI
13 Gao, Y., Ding, Y., Chen, H., Chen, H. and Zhou, J. 2015. Targeting Kruppel-like factor 5 (KLF5) for cancer therapy. Curr. Top. Med. Chem. 15, 699-713.   DOI
14 Adereth, Y., Dammai, V., Kose, N., Li, R. and Hsu, T. 2005. RNA-dependent integrin alpha3 protein localization regulated by the muscleblind-like protein MLP1. Nat. Cell Biol. 7, 1240-1247.   DOI
15 Biasin, M., Sironi, M., Saulle, I., de Luca, M., la Rosa, F., Cagliani, R., Forni, D., Agliardi, C., lo Caputo, S., Mazzotta, F., Trabattoni, D., Macias, J., Pineda, J. A., Caruz, A. and Clerici, M. 2013. Endoplasmic reticulum aminopeptidase 2 haplotypes play a role in modulating susceptibility to HIV infection. AIDS 27, 1697-1706.   DOI
16 Ehsani, A., Alluin, J. V. and Rossi, J. J. Cell cycle abnormalities associated with differential perturbations of the human U5 snRNP associated U5-200kD RNA helicase. 2013. PLoS One 29, e62125.