Effects of Ginseng Berry Water Extract on the Polysaccharide Hydrolysis of Extracellular Enzymes and Intracellular PTP1B and AKT1 |
Kwon, Eun-Jeong
(Department of Chemistry, Dong-Eui University)
Hong, Sugyeong (Department of Chemistry, Dong-Eui University) Kim, Moon-Moo (Department of Chemistry, Dong-Eui University) Kim, Joo Wan (Bioport Korea Ltd.) Kim, Deok Won (Department of Clinical Laboratory Science, Dong-Eui University) Chung, Kyung Tae (Department of Clinical Laboratory Science, Dong-Eui University) |
1 | Gum, R. J., Gaede, L. L., Koterski, S. L., Heindel, M., Clampit, J. E., Zinker, B. A., Trevillyan, J. M., Ulrich, R. G., Jirousek, M. R. and Rondinone, C. M. 2003. Reduction of protein tyrosine phosphatase 1B increases insulin-dependent signaling in ob/ob mice. Diabetes 52, 21-28. DOI ScienceOn |
2 | Allard, M., Schonekess, B., Henning, S., English, D. and Lopaschuk, G. D. 1994. Contribution of oxidative metabolism and glycolysis to ATP production in hypertrophied hearts. Am J Physiol 267, H742-H750. |
3 | Beckman, J. A., Creager, M. A. and Libby, P. 2002. Diabetes and atherosclerosis: epidemiology, pathophysiology, and management. JAMA 287, 2570-2581. DOI ScienceOn |
4 | Block, K. I. and Mead, M. N. 2003. Immune system effects of echinacea, ginseng, and astragalus: a review. Integr Cancer Ther 2, 247-267. DOI ScienceOn |
5 | Brownlee, M. 2001. Biochemistry and molecular cell biology of diabetic complications. Nature 414, 813-820. DOI ScienceOn |
6 | Hansen, M. B., Nielsen, S. E. and Berg, K. 1989. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J Immunol Methods 119, 203-210. DOI ScienceOn |
7 | Hay, N. 2011. Akt isoforms and glucose homeostasis-the leptin connection. Trends Endocrinol Metab 22, 66-73. DOI |
8 | Jeon, H., Kim, S. and Jung, N. 1991. Effects of ginseng saponin fraction and cyclophosphamide on the tumoricidal activity of mouse macrophage and the antitumor effect. Korean J Ginseng Sci 15, 99-105. |
9 | Johnson, T. O., Ermolieff, J. and Jirousek, M. R. 2002. Protein tyrosine phosphatase 1B inhibitors for diabetes. Nature Reviews Drug Discov 1, 696-709. DOI ScienceOn |
10 | Koren, S. and Fantus, I. G. 2007. Inhibition of the protein tyrosine phosphatase PTP1B: potential therapy for obesity, insulin resistance and type-2 diabetes mellitus. Best Pract Res Clin Endocrinol Metab 21, 621-640. DOI ScienceOn |
11 | Kulkarni, R. N., Brüning, J. C., Winnay, J. N., Postic, C., Magnuson, M. A. and Kahn, C. R. 1999. Tissue-Specific Knockout of the Insulin Receptor in Pancreatic Cells Creates an Insulin Secretory Defect Similar to that in Type 2 Diabetes. Cell 96, 329-339. DOI ScienceOn |
12 | Lee, J. and Pilch, P. 1994. The insulin receptor: structure, function, and signaling. Am J Physiol 266, C319-C334. DOI |
13 | Saltiel, A. R. and Kahn, C. R. 2001. Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414, 799-806. DOI ScienceOn |
14 | Lee, S. Y., Kim, Y. K., Park, N. I., Kim, C. S., Lee, C. Y. and Park, S. U. 2010. Chemical constituents and biological activities of the berry of Panax ginseng. J Med Plant Res 4, 349-353. |
15 | Van Der Maarel, M. J., Van Der Veen, B., Uitdehaag, J., Leemhuis, H. and Dijkhuizen, L. 2002. Properties and applications of starch-converting enzymes of the -amylase family. J Biotechnol 94, 137-155. DOI ScienceOn |
16 | Moon, J. Y. 2009. Review on the Current Research of Korean Ginseng for its Antidiabetic Activity. Korean Ginseng Res Ind 3, 19-26. |
17 | Park, E. Y., Kim, H. J., Kim, Y. K., Park, S. U., Choi, J. E., Cha, J. Y. and Jun, H. S. 2012. Increase in Insulin Secretion Induced by Panax ginseng Berry Extracts Contributes to the Amelioration of Hyperglycemia in Streptozotocin-induced Diabetic Mice. J Ginseng Res 36, 153-160. DOI ScienceOn |
18 | Sun, C., Zhang, F., Ge, X., Yan, T., Chen, X., Shi, X. and Zhai, Q. 2007. SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B. Cell Metab 6, 307-319. DOI ScienceOn |
19 | Wang, C. Z., Zhang, B., Song, W. X., Wang, A., Ni, M., Luo, X., Aung, H. H., Xie, J. T., Tong, R., He, T. C. and Yuan, C. S. 2006. Steamed American ginseng berry: ginsenoside analyses and anticancer activities. J Agric Food Chem 54, 9936-9942. DOI ScienceOn |
20 | Wang, Y. -J., Zheng, Y. -G., Xue, Y. -P., Wang, Y. -S. and Shen, Y. -C. 2011. Analysis and determination of anti-diabetes drug acarbose and its structural analogs. Curr Pharm Anal 7, 12-20. DOI ScienceOn |
21 | Wolf, G. 2007. Serum retinol-binding protein: a link between obesity, insulin resistance, and type 2 diabetes. Nutr Rev 65, 251-256. DOI ScienceOn |
22 | Zhang, S. and Zhang, Z. -Y. 2007. PTP1B as a drug target: recent developments in PTP1B inhibitor discovery. Drug Discov Today 12, 373-381. DOI ScienceOn |
23 | Zinker, B. A., Rondinone, C. M., Trevillyan, J. M., Gum, R. J., Clampit, J. E., Waring, J. F., Xie, N., Wilcox, D., Jacobson, P. and Frost, L. 2002. PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice. Proc Natl Acad Sci USA 99, 11357-11362. DOI ScienceOn |
24 | Attele, A. S., Zhou, Y. -P., Xie, J. -T., Wu, J. A., Zhang, L., Dey, L., Pugh, W., Rue, P. A., Polonsky, K. S. and Yuan, C. -S. 2002. Antidiabetic effects of Panax ginseng berry extract and the identification of an effective component. Diabetes 51, 1851-1858. DOI ScienceOn |