Pro-apoptotic and Anti-adipogenic Effects of Proso Millet (Panicum miliaceum) Grains on 3T3-L1 Preadipocytes
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Jun, Do Youn
(School of Life Science and Biotechnology, College of Natural Sciences, Kyungpook National University)
Lee, Ji Young (School of Life Science and Biotechnology, College of Natural Sciences, Kyungpook National University) Han, Cho Rong (School of Life Science and Biotechnology, College of Natural Sciences, Kyungpook National University) Kim, Kwan-Pil (Lotte Confectionary Co., LTD.) Seo, Myung Chul (Crop Environment Division, NICS, RDA.) Nam, Min Hee (Functional Cereal Crop Research Division, NICS, RDA.) Kim, Young Ho (School of Life Science and Biotechnology, College of Natural Sciences, Kyungpook National University) |
1 | Hirata, T., Fujii, M., Akita, K., Yanaka, N., Ogawa, K., Kuroyanagi, M. and Hongo, D. 2009. Identification and physiological evaluation of the components from citrus fruits as potential drugs for anti-corpulence and anticancer. Bioorg Med Chem 17, 25-28. DOI ScienceOn |
2 | Ha, Y. D. and Lee, S. P. 2001. Characteristics of proteins in Italian millet, sorghum and common millet. Korean J Postharvest Sci Technol 8, 187-192. 과학기술학회마을 |
3 |
Hemati, N., Ross, S. E., Erickson, R. L., Groblewski, G. E. and MacDougald, O. A. 1997. Signaling pathways through which insulin regulates ccaat/enhancer binding protein alpha (C/ |
4 | Hirahatake, K. M., Slavin, J. L., Maki, K. C. and Adams, S. H. 2014. Associations between dairy foods, diabetes, and metabolic health: potential mechanisms and future directions. Metabolism 63, 618-627. DOI ScienceOn |
5 | Jun, D. Y., Han, C. R., Choi, M. S., Bae, M. A., Woo, M. H. and Kim, Y. H. 2011. Effect of mollugin on apoptosis and adipogenesis of 3T3-L1 preadipocytes. Phytother Res 25, 724-731. DOI ScienceOn |
6 | Kalinova, J. and Moudry, J. 2006. Content and quality of protein in Proso millet (Panicum miliaceum L.) varieties. Plant Foods for Human Nutrition 61, 45-49. |
7 | Kil, H. Y., Seong, E. S., Ghimire, B. K., Chung, I. M., Kwon, S. S., Goh, E. J., Heo, K., Kim, M. J., Lim, J. D., Lee, D. and Yu, C. Y. 2009. Antioxidant and antimicrobial activities of crude sorghum extract. Food Chem 115, 1234-1239. DOI ScienceOn |
8 | Kwak, C. S., Lim, S. J., Kim, S. A., Park, S. C. and Lee, M. S. 2004. Antioxidative and antimutagenicity effects of Korean buckwheat, sorghum, millet, and Job's tears. J Korean Soc Food Sci Nutr 33, 921-929. DOI |
9 | Ambati, S., Yang, J. Y., Rayalam, S., Park, H. J., Della-Fera, M. A. and Baile, C. A. 2009. Ajoene exerts potent effects in 3T3-L1 adipocytes by inhibiting adipogenesis and inducing apoptosis. Phytother Res 23, 513-518. DOI ScienceOn |
10 | Ahn, J., Lee, H., Kim, S. and Ha, T. 2010. Curcumin-induced suppression of adipogenic differentiation is accompanied by activation of Wnt/beta-catenin signaling. Am J Physiol Cell Physiol 298, 1510-1516. |
11 | Anderson, J. W. 2003. Whole grains protect against atherosclerotic cardiovascular disease. Proc Nutr Soc 62, 135-142. DOI ScienceOn |
12 | Awika, J. M. and Rooney, L. W. 2004. Sorghum phytochemicals and their potential impact on human health. Phytochemistry 65, 1199-1221. DOI ScienceOn |
13 | Camp, H. S., Ren, D. and Leff, T. 2002. Adipogenesis and fat-cell function in obesity and diabetes. Trends Mol Med 8, 442-447. DOI ScienceOn |
14 | Chandrasekara, A. and Shahidi, F. 2010. Content of insoluble bound phenolics in millets and their contribution to antioxidant capacity. J Agric Food Chem 58, 6706-6714. DOI ScienceOn |
15 | Shimanuki, S., Nagasawa, T. and Nishizawa, N. 2006. Plasma HDL subfraction levels increase in rats fed proso-millet protein concentrate. Med Sci Monit 12, 221-226. |
16 | Couillard, C., Mauriege, P., Imbeault, P., Prudhomme, D., Nadeau, A., Tremblay, A., Bouchard, C. and Despres, J. P. 2000. Hyperleptinemia is more closely associated with adipose cell hypertrophy than with adipose tissue hyperplasia. Int J Obes Relat Metab Disord 24, 782-788. DOI ScienceOn |
17 | Gregoire, F. M. 2001. Adipocyte differentiation: from fibroblast to endocrine cell. Exp Biol Med 226, 997-1002. |
18 | Sun, X. M., MacFarlane, M., Zhuang, J., Wolf, B. B., Green, D. R. and Cohen, G. M. 1999. Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis. J Biol Chem 274, 5053-5040. DOI ScienceOn |
19 | Slavin, J. 2003. Why whole grains are protective: biological mechanisms. Proc Nutr Soc 62, 129-134. DOI ScienceOn |
20 | Slavin, J. L., Martini, M. C., Jacobs, D. R. Jr. and Marquart, L. 1999. Plausible mechanisms for the protectiveness of whole grains. Am J Clin Nutr 70, 459-463. DOI |
21 | Tamori, Y., Masugi, J., Nishino, N. and Kasuga, M. 2002. Role of peroxisome proliferator-activated receptor-gamma in maintenance of the characteristics of mature 3T3-L1 adipocytes. Diabetes 51, 2045-2055. DOI ScienceOn |
22 | Urizar, N. L. and Moore, D. D. 2003. GUGULIPID: a natural cholesterol-lowering agent. Annu Rev Nutr 23, 303-313. DOI ScienceOn |
23 | Visscher, T. L. and Seidell, J. C. 2001. The public health impact of obesity. Annu Rev Public Health 22, 355-75. DOI ScienceOn |
24 | Park, M. Y., Kim, J. H. and Park, D. S. 2011. Anti-inflammatory activities of hog millet (Panicum miliaceum L.) in murine macrophages through IRAK-4 signaling. Korean J Food Nutr 24, 268-272. 과학기술학회마을 DOI ScienceOn |
25 | Park, M. Y., Jang, H. H, Kim, J. B., Yoon, H. N., Lee, J. Y., Lee, Y. M., Kim, J. H, and Park, D. S. 2011. Hog millet (Panicum miliaceum L.)-supplemented diet ameliorates hyperlipidemia and hepatic lipid accumulation in C57BL/6J-ob/ob mice. Nutr Res Pract 5, 511-519. 과학기술학회마을 DOI |
26 | Park, D. H., Lee, S. T., Jun, D. Y., Lee, J. Y., Woo, M. H., Kim, K. Y., Seo, M. C., Ko, J. Y., Woo, K. S., Jung, T. W., Kwak, D. Y., Nam, M. H. and Kim, Y. H. 2014. Comparative evaluation of antioxidant activities of ethanol extracts and their solvent fractions obtained from selected miscellaneous cereal grains. J Life Sci 24, 26-38. 과학기술학회마을 DOI ScienceOn |
27 | Park, K. O., Ito, Y., Nagasawa, T., Choi, M. R. and Nishizawa, N. 2008. Effects of dietary Korean proso-millet protein on plasma adiponectin, HDL cholesterol, insulin levels, and gene expression in obese type 2 diabetic mice. Biosci Biotechnol Biochem 72, 2918-2925. DOI ScienceOn |
28 | Park, M. Y., Seo, D. W., Lee, J. Y., Sung, M. K., Lee, Y. M., Jang, H. H., Choi, H. Y, Kim, J. H. and Park, D. S. 2011. Effects of Panicum miliaceum L. extract on adipogenic transcription factors and fatty acid accumulation in 3T3-L1 adipocytes. Nutr Res Pract 5, 192-197. 과학기술학회마을 DOI |
29 | Rosen, E. D. and MacDougald, O. A. 2006. Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol 7, 885-896. DOI ScienceOn |
30 | Savill, J. and Fadok, V. 2000. Corpse clearance defines the meaning of cell death. Nature 407, 784-788. DOI ScienceOn |
31 | Lazebnik, Y. A., Kaufmann, S. H., Desnoyers, S., Poirier, G. G. and Earnshaw, W. C. 1994. Cleavage of poly (ADP-ribose) polymerase by a proteinase with properties like ICE. Nature 371, 346-347. DOI ScienceOn |
32 | Lu, H., Zhang, J., Liu, K. B., Wu, N., Li. Y., Zhou, K., Ye., M., Zhang, T., Zhang, H., Yang, X., Shen, L., Xu, D. and Li, Q. 2009. Earliest domestication of common millet (Panicum miliaceum) in East Asia extended to 10,000 years ago. Proc Natl Acad Sci USA 106, 7367-7372. DOI ScienceOn |
33 | Kweon, Y. M. and Park, K. Y. 1998. Antimutagenic and anticarcinogenic effect of sorghum. J Cancer Prev 3, 128-135. |
34 | Lazar, M. A. 2002. Becoming fat. Gene Dev 16, 1-5. DOI ScienceOn |
35 | Marquart, L., Jacobs, D. R. Jr. and Slavin, J. L. 2000. Whole grains and health. J Am Coll Nutr 19, 289-290. DOI |
36 | Nagata, S. 1997. Apoptosis by death factor. Cell 88, 355-365. DOI ScienceOn |
37 | Nakazato, K., Song, H. and Waga, T. 2006. Effects of dietary apple polyphenol on adipose tissues weights in Wistar rats. Exp Anim 55, 383-389. DOI ScienceOn |
38 | Nishizawa, N., Sato, D., Ito, Y., Nagasawa, T., Hatakeyama, Y., Choi, M. R., Choi, Y. Y. and Wei, Y. M. 2002. Effects of dietary protein of proso millet on liver injury induced by D-galactosamine in rats. Biosci Biotechnol Biochem 66, 92-96. DOI ScienceOn |
39 | Nishizawa, N., Shimanuki, S., Fujihashi, H., Watanab, H., Fudamoto, Y. and Nagasawa, T. 1996. Proso millet protein elevates plasma level of high-density lipoprotein: a new food function of proso millet. Biomed Environ Sci 9, 209-212. |
40 | Kurosaka, K., Takahashi, M., Watanabe, N. and Kobayashi Y. 2003. Silent cleanup of very early apoptotic cells by macrophages. J Immunol 171, 4672-4679. DOI |
41 | Sahyoun, N. R., Jacques, P. F., Zhang, X. L., Juan, W. and McKeown, N. M. 2006. Whole-grain intake is inversely associated with the metabolic syndrome and mortality in older adults. Am J Clin Nutr 83, 124-131. |
42 | McKeown, N. M., Meigs, J. B., Liu, S., Wilson, P. W and Jacques, P. F. 2002. Whole-grain intake is favorably associated with metabolic risk factors for type 2 diabetes and cardiovascular disease in the framingham offspring study. Am J Clin Nutr 76, 390-398. |
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