Browse > Article
http://dx.doi.org/10.5352/JLS.2014.24.3.318

Serological Investigation of the Infection Rate of Chlamydophila pneumonia among Residents of a Single University Dormitory  

Ryu, Jea Ki (Department of Biomedical Laboratory Science, Gimcheon University)
Kim, Hyun-Kyung (Department of Biomedical Laboratory Science, Gimcheon University)
Kim, Dong-Chan (Department of Biomedical Laboratory Science, Gimcheon University)
Lee, Suk Jun (Department of Biomedical Laboratory Science, Cheongju University)
Publication Information
Journal of Life Science / v.24, no.3, 2014 , pp. 318-322 More about this Journal
Abstract
Chlamydophila pneumonia is a common cause of community-acquired pneumonia throughout the world. It causes mild pneumonia or bronchitis in adolescents and young adults. Older adults may experience more severe disease and repeated infections. To the best of our knowledge, no study has attempted to investigate the prevalence of C. pneumonia in a closed community in Korea. We compared the infection rate of C. pneumonia among university dormitory residents using the miro-immunofluorescence (MIF) method. Antibody titers of IgG (1:32 or more) indicate past infection of C. pneumonia. A recent infection was defined as serum with a high titer of IgG (1:512 or more) or a positive IgM (1:16 or more). The past infection rate of C. pneumonia among the university dormitory residents was 71.7%. The recent infection rate of C. pneumonia according to IgG and IgM titers was 28.3% and 23.3%, respectively. The past infection positive rate according to the number of residence months was 1 month (50%), 7 months (71.4%), 13 months (66.7%), and 35 months (89.5%). The recent infection positive rate according to IgG antibody titers was 1 month (50%), 7 months (28.6%), 13 months (33.3%), and 35 months (10.5%). The recent infection rate of C. pneumonia according to IgM antibody titers was 1 month (41.7%), 7 months (28.6%), 13 months (26.7%), and 35 months (5.3%). The results suggest that the past infection rate of C. pneumonia is increased by the number of residence months in a closed community and that the recent infection rate of C. pneumonia according to IgG and IgM serological tests is decreased by the number of residence months.
Keywords
Chlamydophila pneumonia; infection rate; residence months; university dormitory residents;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 Smieja, M., Mahony, J. B., Goldsmith, C. H., Chong, S., Petrich, A. and Cherneskt, M. 2001. Replicate PCR testing and probit analysis for detection and quantitation of Chlamydia pneumoniae in clinical specimens. J Clin Microbiol 39, 1796-1801.   DOI   ScienceOn
2 Waites, K. B. and Talkington, D. F. 2004. Mycoplasma pneumoniae and its role as a human pathogen. Clin Microbial Rev 17, 697-728.   DOI   ScienceOn
3 Cho, T. Y. 2000. Chlamydia. Korean J Clin Microbiol 3, 1-4.
4 Choi, T. Y., Kim, D. A., Kim, S. K., Kang, J. O., Park, S. S and Jung, S. R. 1998. Prevalence of specific antibodies to Chlamydia pneumoniae in Korea. J Clin Microbiol 36, 3426-3428.
5 Boman, J., Gaydos, C. A. and Quinn, T. C. 1999. Molecular diagnosis of Chlamydia pneumoniae Infection. J Clin Microbiol 37, 3791-3799.
6 Chong, Y. S., Lee, K. W., Kim, H. S., Kwon, O. H. and Cho, S. N. 1993. Prevalence of antibodies against Chlamydia pneumoniae among blood donors and patients with tests of blood chemistry and Mycoplasma pneumoniae antibody. Korean J Infect Dis 25, 131-138.
7 Everett, K. D., Bush, R. M. and Anderson, A. A. 1999. Emended description of the order Chlamydiales, proposal of Parachlamydiaceae fam. nov. and Simkaniaceae fam. nov., each containing one monotypic genus, revised taxonomy of the family Chlamydiaceae, including a new genus and five new species, and standards for the identification of organisms. Int J Syst Bacteriol 49, 415-440.   DOI   ScienceOn
8 Grayston, J. T. 2000. Background and current knowledge of Chlamydia pneumonia and atherosclerosis. J Infect Dis 181, 402-410.   DOI   ScienceOn
9 Hammerschlag, M. R. 2002. The intracellular life of chlamydiae. Semin Pediatr Infect Dis 13, 239-248.   DOI   ScienceOn
10 Hyman, C. L., Augenbraun, M. H., Roblin, P. M., Schachter, J. and Hammerschlag, M. R. 1991. Asymptomatic respiratory tract infection with Chlamydia pneumoniae TWAR. J Clin Microbiol 29, 2082-2083.
11 Kim, K. W. and Kim, K. E. 2009. Mycoplasma and chlamydia infection in Korea. Korean J Pediatr 52, 277-282.   DOI   ScienceOn
12 Kim, M. H. and Lee, W. K. 2010. Comparison of collagen- coated polyethylene terephthalate disc plate and shell vial culture method for the isolation of Chlamydophila pneumoniae. Korean J Clin Microbiol 13, 73-78.   DOI   ScienceOn
13 Blasi, F., Tarsia, P. and Aliberti, S. 2009. Chlamydophila pneumoniae. Clin Microbiol Infect 15, 29-35.
14 Kim, S. J., Kim, Y. J., Maeng, K. Y., Park, C. K., and Choi, T. Y. 2000. Detection of Chlamydia pneumoniae in the Atherosclerotic tissue by immunohistochemistry. Korean J Clin Pathol 20, 41-47.
15 Wong, Y. K., Dawkins, K. D. and Ward, M. E. 1999. Circulating Chlamydia pneumoniae DNA as predictor of coronary artery disease. J Am Coll Cardiol 34, 1435-1439.   DOI   ScienceOn
16 Lee, S. R., Keum, D. G. and Choi, T. Y. 1984. Electron microscopic observation of Chlamydia pneumoniae. Korean J Clin Pathol 17, 146-154.
17 Kuo, C. C., Jackson, L. A., Campbell, L. A. and Grayston, J. T. 1995. Chlamydia pneumoniae (TWAR). Clin Microbiol Rev 8, 451-461.
18 Lee, H. S., Chun, B. Y., Jin, S. H. and Lee, W. K. 2004. Infection rate of Chlamydia pneumoniae by serological antibody test between patients with respiratory symptoms and control group. Korean J Clin Microbiol 7, 31-37.
19 Kobayashi, S., Morichita, T., Miyake, T., Fukushi, H., Hirai, K., Ishihara, Y. and Isomura, S. 1991. Prevalence of Chlamydia pneumoniae in Japan. J Invect Dis 163, 417-418.   DOI   ScienceOn
20 Lee, W. K., Kwon, E. H., Bae, H. G., Suh, J. S., Song, K. E., Lee, N. Y., Won, D. I. and Lee, J. B. 2003. Detection of Chlamydophila pneumoniae in Acute Myocardial Infarction. Korean J Clin Microbiol 6, 81-87.
21 Marton, A., Karolyi, A. and Szalka, A. 1992. Prevalence of Chlamydia pneumoniae antibodies in Hungary. Eur J Clin Microbiol Infect Dis 11, 139-142.   DOI
22 Schachter, J. and Caldwell, H. D. 1980. Chlamydiae. Ann Rev Mcirobiol 34, 285-309.   DOI   ScienceOn
23 Yum, H. Y., Choi, J. Y., Rheu, J. W, Lee, K. E., Kim, C. H., Shon, M. H., Kim, K. E and Lee, K. Y. 2000. Correlation between Chlamydia pneumoniae infection and childhood asthma. Korean J Pediatr Allergy Respir Dis 10, 218-224.