Effects of Platycodon grandiflorum on the Induction of Autophagy and Apoptosis in HCT-116 Human Colon Cancer Cells
![]() |
Hong, Su Hyun
(Department of Biochemistry, Dongeui University College of Korean Medicine)
Park, Cheol (Department of Molecular Biology, College of Natural Science and Human Ecology, Dongeui University) Han, Min Ho (Department of Biochemistry, Dongeui University College of Korean Medicine) Kim, Hong Jae (Department of Pharmacy, College of Pharmacy, Busan University) Lee, Moon Hee (Anti-Aging Research Center & Blue-Bio Industry RIC, Dongeui University) Choi, Yung Hyun (Department of Biochemistry, Dongeui University College of Korean Medicine) |
1 | Chen, N. and Karantza, V. 2011. Autophagy as a therapeutic target in cancer. Cancer Biol Ther 11, 157-168. DOI ScienceOn |
2 | Choi, S., Lim, M. H., Kim, K. M., Jeon, B. H., Song, W. O. and Kim, T. W. 2011. Cordycepin-induced apoptosis and autophagy in breast cancer cells are independent of the estrogen receptor. Toxicol Appl Pharmacol 257, 165-174. DOI |
3 | Nyakudya, E., Jeong, J. H., Lee, N. K. and Jeong, Y. S. 2014. Platycosides from the roots of Platycodon grandiflorum and their health benefits. Prev Nutr Food Sci 19, 59-68. 과학기술학회마을 DOI ScienceOn |
4 | Rosenfeldt, M. T. and Ryan, K. M. 2009. The role of autophagy in tumour development and cancer therapy. Expert Rev Mol Med 11, e36. DOI ScienceOn |
5 | Xi, G., Hu, X., Wu, B., Jiang, H., Young, C. Y., Pang, Y. and Yuan, H. 2011. Autophagy inhibition promotes paclitaxel-induced apoptosis in cancer cells. Cancer Lett 307, 141-148. DOI ScienceOn |
6 | Zhan, Y., Gong, K., Chen, C., Wang, H. and Li, W. 2012. P38 MAP kinase functions as a switch in MS-275-induced reactive oxygen species-dependent autophagy and apoptosis in human colon cancer cells. Free Radic Biol Med 53, 532-543. DOI |
7 | Lee, J. W., Park, C., Han, M. H., Hong, S. H., Lee, T. K., Lee, S. H., Kim, G. Y. and Choi, Y. H. 2013. Induction of human leukemia U937 cell apoptosis by an ethanol extract of Dendropanax morbifera Lev. through the caspase-dependent pathway. Oncol Rep 30, 1231-1238. DOI |
8 | Codogno, P. and Meijer, A. J. 2005. Autophagy and signaling: their role in cell survival and cell death. Cell Death Differ 12, 1509-1518. DOI ScienceOn |
9 | Cuervo, A. M. and Macian, F. 2011. Autophagy, nutrition and immunology. Mol Aspects Med 33, 2-13. |
10 | Delavari, A., Mardan, F., Salimzadeh, H., Bishehsari, F., Khosravi, P., Khanehzad, M., Nasseri-Moghaddam, S., Merat, S., Ansari, R., Vahedi, H., Shahbazkhani, B., Saberifiroozi, M., Sotoudeh, M. and Malekzadeh, R. 2014. Characteristics of colorectal polyps and cancer; a retrospective review of colonoscopy data in iran. Middle East J Dig Dis 6, 144-150. |
11 | Jeong, S. Y. and Seol, D. W. 2008. The role of mitochondria in apoptosis. BMB Rep 41, 11-22. DOI |
12 | Kimmelman, A. C. 2011. The dynamic nature of autophagy in cancer. Genes Dev 25, 1999-2010. DOI ScienceOn |
13 | Lee, J. Y., Lee, J. M., Lee, C. H., C, J. H., Jang, J. B. and Lee, K. S., 2010. Antitumor and immunomodulatory activities of Platycodon grandiflorum. J Orient Obstet Gynecol 23, 10-19. 과학기술학회마을 |
14 | Levine, B. and Kroemer, G. 2008. Autophagy in the pathogenesis of disease. Cell 132, 27-42. DOI ScienceOn |
15 | Mizushima, N., Yoshimorim, T. and Levine, B. 2010. Methods in mammalian autophagy research. Cell 140, 313-326. DOI ScienceOn |
16 | Kroemer, G., Galluzzi, L., Vandenabeele, P., Abrams, J., Alnemri, E. S., Baehrecke, E. H., El-Deiry, W. S., Golstein, P., Green, D. R., Hengartner, M., Knight, R. A., Kumar, S., Lipton, S. A., Malorni, W., Nunez, G., Peter, M. E., Tschopp, J., Yuan, J., Piacentini, M., Zhivotovsky, B. and Melino, G. 2009. Classification of cell death: recommendations of the nomenclature committee on cell death 2009. Cell Death Differ 16, 3-11. DOI ScienceOn |
![]() |